Sybrava 284mg/1.5 ml Pre-Filled Syringe

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Sybrava 284mg/1.5 ml Pre-Filled Syringe is a prescription-only medicine (POM) presented as a medicine, with Inclisiran (sodium) 284mg/1.5ml as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

This medicine is administered only by a doctor or nurse as a subcutaneous injection, usually into the abdomen; it is not self-administered at home. Continue any statin or other cholesterol medicine as prescribed alongside this treatment.

Dosage

The regimen is a subcutaneous injection given by a healthcare professional at the start of treatment, again three months later, and then once every six months thereafter; the treating doctor confirms this schedule is appropriate alongside your other lipid-lowering therapy.

Shelf Life

Refer to the expiry date printed on the packaging; this medicine is stored and administered only by healthcare professionals.

Storage Instructions

Stored under controlled, refrigerated conditions by the pharmacy or clinic as specified by the manufacturer; not intended for home storage.

Side Effects

  • Injection site reactions – redness, pain, or swelling
  • Joint pain (arthralgia)
  • Urinary tract infection
  • Diarrhoea
  • Bronchitis or upper respiratory infection symptoms

Contraindications

  • Known hypersensitivity to inclisiran or any ingredient in the formulation
  • Pregnancy and breastfeeding, unless specifically directed by the treating doctor

Drug / Food Interactions

  • No major drug-drug interactions have been identified, as inclisiran is not metabolised through the liver enzyme pathways that many other medicines use.
  • It is intended to be used alongside statins and other standard lipid-lowering therapy, not as a replacement for them.
  • Inform your doctor of all medicines and supplements you are taking.

Quick Tips

  • Keep every scheduled injection appointment, as the twice-yearly maintenance schedule depends on consistent timing.
  • Continue your statin or other prescribed cholesterol medicine alongside this treatment unless your doctor advises otherwise.
  • Report persistent injection site reactions to your care team.
  • Attend scheduled cholesterol level checks so your doctor can assess your response to treatment.

Frequently Asked Questions

Is Sybrava 284mg/1.5 ml Pre-Filled Syringe a prescription medicine?

Yes. Sybrava 284mg/1.5 ml Pre-Filled Syringe is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Sybrava 284mg/1.5 ml Pre-Filled Syringe contain?

Sybrava 284mg/1.5 ml Pre-Filled Syringe is supplied as a medicine and contains Inclisiran (sodium) 284mg/1.5ml. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Sybrava 284mg/1.5 ml Pre-Filled Syringe is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Sybrava 284mg/1.5 ml Pre-Filled Syringe?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Sybrava 284mg/1.5 ml Pre-Filled Syringe?

Stored under controlled, refrigerated conditions by the pharmacy or clinic as specified by the manufacturer; not intended for home storage. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Sybrava 284mg/1.5 ml Pre-Filled Syringe on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Sybrava 284mg/1.5 ml Pre-Filled Syringe?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Sybrava 284mg/1.5 ml Pre-Filled Syringe be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Sybrava 284mg/1.5 ml Pre-Filled Syringe registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Inclisiran (sodium) 284mg/1.5ml

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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