Is Tagrisso 40mg Tablet a prescription medicine?

Yes. Tagrisso 40mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Tagrisso 40mg Tablet contain?

Tagrisso 40mg Tablet is supplied as a tablet and contains Osimertinib (as mesilate) 40mg. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Tagrisso 40mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Tagrisso 40mg Tablet?

Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Tagrisso 40mg Tablet?

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Tagrisso 40mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Tagrisso 40mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor. Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Tagrisso 40mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Tagrisso 40mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

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Tagrisso 40mg Tablet

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Manufacturer AstraZeneca

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: October 18, 2026

Overview

Tagrisso 40mg Tablet contains Osimertinib (as mesilate) 40mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Tagrisso 40mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take the tablet at about the same time each day, with or without food, and swallow it whole; if swallowing whole is difficult, ask your oncology team how it may be dispersed, rather than crushing or chewing it yourself.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

Diarrhoea
Rash or dry skin
Nail changes
Fatigue
Cough
Low white blood cell count
Decreased appetite
Shortness of breath

Contraindications

Known hypersensitivity to osimertinib or any ingredient in the tablet
Use in pregnancy without specialist guidance, due to potential harm to the foetus

Drug / Food Interactions

Strong inducers of the CYP3A4 enzyme (such as rifampicin, carbamazepine, and St John’s Wort) can lower osimertinib levels and are generally avoided.
Osimertinib can affect the levels of some other medicines that depend on certain transporter proteins – your oncology team will review your full medicine list.
Medicines that prolong the QT interval should be used cautiously alongside osimertinib.
Inform your oncology team of all medicines and supplements you are taking.

Quick Tips

Contact your oncology team immediately if you develop new or worsening breathlessness, cough, or fever, as these can signal a rare but serious lung side effect.
Attend all scheduled heart (ECG) and blood monitoring appointments during treatment.
Use gentle skin and nail care, and tell your care team if rash or nail problems become uncomfortable.
Never stop or change the dose on your own – discuss any side effects with your oncology team first.

Ingredients / Active Ingredients

Osimertinib

Osimertinib (as mesilate) 40mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

Brand	AstraZeneca
Manufacturer	AstraZeneca
Classification	Prescription medicine
Ingredients / Active Ingredients	Osimertinib
Pack Size	30s
Dosage	The usual dose is one tablet once daily, but the exact dose, duration, and any interruption or reduction is individualised and monitored by the treating oncologist based on response and side effects.
Shelf Life	Refer to the expiry date printed on the packaging.