Tri-Luma Cream

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Manufacturer Galderma
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  • Muslim-Friendly
  • FDA Approved
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Tri-Luma Cream is a prescription-only medicine (POM) that contains Hydroquinone 4% w/w, Tretinoin 0.05% w/w and Fluocinolone acetonide 0.01% w/w. It is supplied as a cream and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Tri-Luma Cream is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Wash and pat the face dry, wait 20-30 minutes, then apply a thin layer to the affected areas only, avoiding the eyes, mouth, and any broken skin. Use sun protection during the day, as treated skin is more sensitive to sunlight.

Storage Instructions

Store below 25°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Skin redness, peeling, or dryness
  • Burning or stinging sensation on application
  • Increased sun sensitivity
  • Skin thinning with prolonged use beyond the recommended treatment period
  • Acne-like breakouts

Contraindications

  • Known hypersensitivity to hydroquinone, tretinoin, fluocinolone, or sulfites
  • Pregnancy and breastfeeding
  • Use on sunburned, eczematous, or broken skin
  • Children

Drug / Food Interactions

  • Other topical acne or exfoliating products (such as benzoyl peroxide or other retinoids): combined use increases skin irritation and dryness.
  • Other topical corticosteroids: avoid applying additional steroid products to the same area to reduce the risk of skin thinning.
  • Products containing peroxide: may temporarily discolour skin or fabric when combined with tretinoin-containing creams.
  • Inform your doctor of all skin products you are using before starting this cream.

Quick Tips

  • Use sun protection with a broad-spectrum sunscreen and protective clothing daily, as this cream increases skin sensitivity to sunlight.
  • Use only for the treatment duration prescribed – this cream is not intended for continuous long-term use due to the corticosteroid component.
  • Apply only to the pigmented areas as a thin layer; using more than directed does not speed up results and increases irritation.
  • Stop use and consult your doctor if you experience severe redness, swelling, or blistering.

Ingredients / Active Ingredients

  • Hydroquinone 4% w/w
  • Tretinoin 0.05% w/w
  • Fluocinolone acetonide 0.01% w/w

Safety Advice

Pregnancy

Not Advisable

Use during pregnancy is generally not recommended unless absolutely necessary.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Generally Safe

Generally safe, but caution may be required in some patients.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Frequently Asked Questions

Product Specifications

BrandGalderma
ManufacturerGalderma
ClassificationPrescription medicine
Ingredients / Active IngredientsFluocinolone Acetonide + Hydroquinone + Tretinoin
Weight15g
DosageApply a thin layer to the affected areas of the face once daily at bedtime, for a treatment period of up to eight weeks as directed by your doctor – this cream is not intended for long-term continuous use.
Shelf LifeRefer to the expiry date printed on the packaging.

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