Trustiva Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Trustiva Tablet is a fixed-dose combination antiretroviral medicine containing efavirenz, emtricitabine, and tenofovir disoproxil fumarate, used as a complete once-daily regimen to treat HIV-1 infection in adults, either alone or with other antiretroviral medicines as directed by a specialist.

The three medicines work together at different steps of the HIV life cycle: efavirenz and emtricitabine/tenofovir block the virus from copying its genetic material, together suppressing viral replication and helping the immune system recover.

How it Works

Efavirenz is a non-nucleoside reverse transcriptase inhibitor that blocks the reverse transcriptase enzyme HIV needs to convert its RNA into DNA. Emtricitabine and tenofovir disoproxil fumarate are nucleos(t)ide analogues that are incorporated into the growing viral DNA chain, causing it to terminate. Together, these actions suppress the virus’s ability to replicate, keeping viral load low and allowing immune function to be preserved or restored.

Directions for Use

Take the tablet whole with water on an empty stomach, ideally at bedtime, as taking it with a high-fat meal can increase side effects. Take it at the same time every day without missing doses.

Dosage

The usual adult dose is one tablet taken once daily, preferably on an empty stomach and at bedtime, to reduce nervous system side effects. Your specialist confirms the appropriate regimen based on your treatment history.

Shelf Life

Refer to the expiry date printed on the packaging.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea
  • Headache
  • Diarrhea
  • Fatigue
  • Dizziness
  • Abdominal pain
  • Weight loss
  • Rash

Contraindications

  • Known hypersensitivity to efavirenz, emtricitabine, tenofovir disoproxil fumarate, or any excipient
  • Severe liver impairment
  • Co-administration with certain medicines that interact seriously with efavirenz, such as some herbal products (e.g., St. John’s Wort) and specific other medicines identified by your specialist

Drug / Food Interactions

  • St. John’s Wort and certain other herbal or complementary products can significantly reduce efavirenz levels and must be avoided.
  • Efavirenz can affect the levels of many other medicines, including some other antiretrovirals, some anti-tuberculosis medicines, and hormonal contraceptives – use additional barrier contraception.
  • Taking with a high-fat meal can increase absorption of efavirenz and worsen nervous system side effects – take on an empty stomach.
  • Inform your specialist of all medicines, supplements, and herbal products you are taking.

Quick Tips

  • Take this medicine every day exactly as prescribed – missed doses can allow the virus to develop resistance to treatment.
  • Take at bedtime on an empty stomach to reduce dizziness and vivid dreams.
  • Attend all scheduled blood tests to monitor kidney function, bone health, and viral load.
  • This medicine does not cure HIV or prevent transmission to others – continue to practise safe sex and discuss prevention strategies with your specialist.

Frequently Asked Questions

What is Trustiva used for?

Trustiva is a triple-combination antiretroviral tablet used to treat HIV-1 infection in adults as part of a specialist-supervised treatment plan.

How does Trustiva work?

It combines three medicines that block different steps the HIV virus needs to copy itself, suppressing viral replication and helping preserve immune function.

What happens if I miss a dose?

Take it as soon as you remember, but if it is close to your next dose, skip the missed one – do not double up. Missing doses regularly can lead to drug resistance, so try to take it consistently.

Why should I take this medicine on an empty stomach at bedtime?

Taking it on an empty stomach at bedtime reduces nervous system side effects such as dizziness and vivid dreams, which are more pronounced with a high-fat meal.

Does this medicine cure HIV?

No, it does not cure HIV, but it suppresses the virus effectively when taken consistently, helping preserve immune function and reduce transmission risk.

Can I take herbal supplements like St. John’s Wort with this medicine?

No, St. John’s Wort and certain other herbal products can significantly reduce the effectiveness of this medicine and must be avoided.

Do I still need to use protection during sex while on this medicine?

Yes, this medicine does not eliminate the risk of transmitting HIV to others – continue safe sex practices and discuss prevention strategies with your specialist.

Can I buy Trustiva Tablet from DoctorOnCall?

Yes, Trustiva Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Trustiva Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Trustiva Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Trustiva Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Trustiva Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Trustiva Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Efavirenz 600mg
  • Emtricitabine 200mg
  • Tenofovir disoproxil fumarate 300mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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