Vicide 5% Cream

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Vicide 5% Cream is a cream with Acyclovir (aciclovir) 5% declared as its active content. It is supplied in a pack size of 10g.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Wash your hands before use, then dab a small amount of Vicide 5% Cream onto the affected lip area as soon as you notice tingling, itching or redness, reapplying approximately five times a day at roughly four-hour intervals (no need to apply overnight) for about four to five days. Wash your hands again after each application to reduce the chance of spreading the virus to your eyes, other parts of your face, or other people, and avoid sharing items like lipstick, cups or towels while the sore is active.

Dosage

For adults and adolescents, a thin layer of Vicide 5% Cream is usually applied to the affected area five times daily, roughly every four hours, for around five consecutive days; if the cold sore is not resolving within that time, continuing to self-treat without checking with a pharmacist or doctor is not recommended. Use in young children should be discussed with a pharmacist or doctor first.

Shelf Life

When kept unopened and stored as recommended, Vicide 5% Cream generally remains stable until the expiry date printed on the tube and carton. Always check the expiry date before use and discard the cream once it has expired.

Storage Instructions

Store below 25°C in a cool, dry place away from direct sunlight, and close the tube cap firmly after every use to stop the cream from drying out. Keep out of the reach and sight of children.

Side Effects

  • Nausea or vomiting
  • Headache
  • Dizziness
  • Diarrhoea
  • Joint or muscle pain
  • Fatigue or tiredness
  • Mild rash or skin reaction

Contraindications

  • Known allergy or hypersensitivity to acyclovir, valacyclovir, or any excipient in the cream
  • Application inside the mouth, on the eyes, or on mucous membranes
  • Genital sores or lesions, which require medical evaluation rather than a lip-cream product
  • People with significant immune suppression, who should seek medical advice before self-treating

Drug / Food Interactions

  • No clinically meaningful interactions are expected with typical topical use, as systemic absorption through the skin is very limited
  • Avoid layering other creams, lip balms or cosmetics over the treated area at the same time, as this may reduce effectiveness or irritate the skin
  • Check with a pharmacist if you are also using a prescribed oral antiviral for cold sores or shingles

Quick Tips

  • Start treatment the moment you feel tingling or itching, rather than waiting for a blister to appear
  • Apply with a cotton bud or clean fingertip to help avoid spreading the virus to other areas
  • Avoid kissing, sharing utensils, or close facial contact until the sore has fully crusted over and healed
  • Keep a tube on hand if you experience recurrent cold sores, so treatment can begin at the earliest sign
  • Speak to a pharmacist or doctor if sores keep coming back frequently, are unusually large, or are not settling with treatment

Ingredients / Active Ingredients

  • Acyclovir (aciclovir) 5% (active ingredient)
  • Cream base with emulsifying and moisturising components
  • Other pharmaceutical excipients as per the manufacturer's formulation

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

A cold sore remains contagious from the first tingling sensation until it has fully crusted and healed, so careful handwashing and avoiding close contact, especially with newborns and people with weakened immunity, is important during an outbreak. Vicide 5% Cream treats the visible outbreak but does not eliminate the herpes simplex virus itself, which stays dormant in the nerve tissue and can be triggered again by factors such as sun exposure, illness, stress or hormonal changes, which is why recurrent sufferers often keep this cream readily available.

Frequently Asked Questions

Product Specifications

ClassificationNon-prescription
Ingredients / Active IngredientsAcyclovir
Weight10g

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Important Medical Information

💊 Recommended Dosage:

For adults and adolescents, a thin layer of Vicide 5% Cream is usually applied to the affected area five times daily, roughly every four hours, for around five consecutive days; if the cold sore is not resolving within that time, continuing to self-treat without checking with a pharmacist or doctor is not recommended. Use in young children should be discussed with a pharmacist or doctor first.

🛑 Contraindications (Do not use if):
  • Known allergy or hypersensitivity to acyclovir, valacyclovir, or any excipient in the cream
  • Application inside the mouth, on the eyes, or on mucous membranes
  • Genital sores or lesions, which require medical evaluation rather than a lip-cream product
  • People with significant immune suppression, who should seek medical advice before self-treating
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Diarrhoea
  • Joint or muscle pain
  • Fatigue or tiredness
  • Mild rash or skin reaction
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.