Xepa Pristine 2% Shampoo

Brand Xepa
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Xepa Pristine 2% Shampoo is a healthcare product with Ketoconazole 2% w/w declared as its active content. It is supplied in a pack size of 120ml.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Wet the hair and scalp thoroughly, then apply enough Xepa Pristine 2% Shampoo to work up a lather, massaging gently into the scalp for about 3 to 5 minutes to allow the active ingredient to take effect, then rinse thoroughly with water. For dandruff or seborrhoeic dermatitis, it is commonly used twice a week for 2 to 4 weeks, leaving at least 3 days between washes, and then used less often (for example, every 1 to 2 weeks) for maintenance as advised by a doctor or pharmacist. Avoid contact with the eyes; if the shampoo gets into the eyes, rinse thoroughly with water.

Dosage

For treating dandruff or seborrhoeic dermatitis of the scalp, apply Xepa Pristine 2% Shampoo to wet hair and scalp, lather, leave on for about 3 to 5 minutes, then rinse off; use twice weekly for 2 to 4 weeks. For fungal scalp infections, a doctor or pharmacist may recommend a similar or adjusted frequency and duration. Once symptoms are controlled, a less frequent maintenance schedule (such as every 1 to 2 weeks) may be recommended to help prevent recurrence. If there is no improvement after 4 weeks, consult a doctor or pharmacist.

Shelf Life

Xepa Pristine 2% Shampoo is valid for use up to the expiry date printed on the bottle and outer carton when stored correctly and unopened. Check the expiry date before use and discard the product once it has expired or if it shows any unusual change in colour, consistency, or smell after opening.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight. Keep the bottle tightly closed after use. Do not freeze. Keep out of the sight and reach of children.

Side Effects

  • Nausea or vomiting
  • Stomach pain
  • Headache
  • Dizziness
  • Itching or skin rash (when applied topically)
  • Abnormal liver function tests
  • Hair thinning (topical use)

Contraindications

  • Known hypersensitivity or allergy to ketoconazole or other imidazole antifungals
  • Avoid contact with the eyes; rinse immediately with water if accidental contact occurs
  • Not intended for use on broken or actively weeping skin on the scalp without medical advice
  • Pregnant or breastfeeding women should consult a doctor or pharmacist before use
  • Not recommended for young children without medical advice

Drug / Food Interactions

  • Ketoconazole shampoo is used topically on the scalp with minimal systemic absorption, so significant drug interactions are uncommon with normal use
  • Avoid using other medicated shampoos or scalp treatments at the same time unless advised by a pharmacist, as this may increase irritation without added benefit
  • No significant food interactions are expected with topical/scalp use
  • Inform your pharmacist if you are using other topical or oral antifungal treatments

Quick Tips

  • Leave the lather on the scalp for the full 3 to 5 minutes before rinsing to give the active ingredient time to work
  • Use consistently as directed — typically twice a week during the treatment phase — rather than daily, unless told otherwise
  • Avoid getting shampoo in the eyes; rinse well with water if this happens
  • Switch to a less frequent maintenance schedule once symptoms are controlled, as advised by a pharmacist or doctor
  • Avoid sharing towels or hairbrushes if a scalp fungal infection is suspected
  • See a doctor or pharmacist if scalp symptoms do not improve after 4 weeks or if hair loss occurs

Ingredients / Active Ingredients

  • Ketoconazole 2% w/w (active ingredient)
  • Shampoo base formulated for scalp and hair application
  • Surfactant/cleansing agents that help the shampoo lather and rinse clean
  • Thickening and conditioning agents typical of medicated shampoo formulations
  • Preservative system to maintain product stability
  • Purified water as the vehicle base

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Relevant Information

Dandruff and seborrhoeic dermatitis are common, chronic scalp conditions linked to an overgrowth of Malassezia yeast on the skin, and symptoms often flare up periodically even with treatment. Xepa Pristine 2% Shampoo helps control flaking, itching, and inflammation but may need to be used intermittently over the long term to keep symptoms managed. Malaysia’s hot, humid climate can make scalp conditions more prone to flare-ups, so good scalp hygiene alongside treatment is helpful. If the scalp becomes very inflamed, painful, or shows signs of a spreading infection, a doctor should assess it.

Frequently Asked Questions

Product Specifications

BrandXepa
ClassificationNon-prescription
Ingredients / Active IngredientsKetoconazole
Volume120ml

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Important Medical Information

💊 Recommended Dosage:

For treating dandruff or seborrhoeic dermatitis of the scalp, apply Xepa Pristine 2% Shampoo to wet hair and scalp, lather, leave on for about 3 to 5 minutes, then rinse off; use twice weekly for 2 to 4 weeks. For fungal scalp infections, a doctor or pharmacist may recommend a similar or adjusted frequency and duration. Once symptoms are controlled, a less frequent maintenance schedule (such as every 1 to 2 weeks) may be recommended to help prevent recurrence. If there is no improvement after 4 weeks, consult a doctor or pharmacist.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity or allergy to ketoconazole or other imidazole antifungals
  • Avoid contact with the eyes; rinse immediately with water if accidental contact occurs
  • Not intended for use on broken or actively weeping skin on the scalp without medical advice
  • Pregnant or breastfeeding women should consult a doctor or pharmacist before use
  • Not recommended for young children without medical advice
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Stomach pain
  • Headache
  • Dizziness
  • Itching or skin rash (when applied topically)
  • Abnormal liver function tests
  • Hair thinning (topical use)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.