Zestril 5mg Tablet

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Manufacturer AstraZeneca
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Zestril 5mg Tablet is a prescription-only medicine (POM) that contains Lisinopril 5mg (as lisinopril dihydrate). It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Zestril 5mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Zestril 5mg Tablet at about the same time every day, with or without food. Swallow the tablet whole with a glass of water, and do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.

Dosage

The usual starting dose of Zestril 5mg Tablet for hypertension is 10mg once daily, which your doctor may adjust up to 40mg daily depending on your blood pressure response; heart failure dosing is usually started lower and titrated gradually. Always take exactly as prescribed by your doctor.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or lightheadedness
  • Dry cough
  • Headache
  • Fatigue
  • Nausea
  • Low blood pressure
  • Elevated blood potassium levels (hyperkalemia)
  • Rash

Contraindications

  • Known hypersensitivity to lisinopril or any ACE inhibitor
  • History of angioedema related to previous ACE inhibitor treatment, or hereditary/idiopathic angioedema
  • Pregnancy (can cause harm to the developing baby, especially in the second and third trimester)
  • Concomitant use with aliskiren in patients with diabetes or kidney impairment

Drug / Food Interactions

  • Potassium supplements or potassium-sparing diuretics may increase the risk of high blood potassium
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
  • Lithium levels may increase when combined with lisinopril
  • Other blood pressure medicines or diuretics may increase the risk of low blood pressure, especially with the first dose

Quick Tips

  • Take at the same time each day to build a consistent routine
  • Monitor your blood pressure regularly as advised by your doctor
  • Report a persistent dry cough to your doctor, as an alternative medicine may be considered
  • Rise slowly from sitting or lying down to reduce dizziness
  • Do not stop this medicine abruptly without medical advice

Ingredients / Active Ingredients

  • Lisinopril 5mg (as lisinopril dihydrate)

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandAstraZeneca
ManufacturerAstraZeneca
ClassificationPrescription medicine
Ingredients / Active IngredientsLisinopril
Pack Size14s, 28s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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