Zosaar Hct 50/12.5mg Tablet

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Manufacturer Avo
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Zosaar Hct 50/12.5mg Tablet is a prescription-only medicine (POM) that contains Losartan potassium 50mg and Hydrochlorothiazide 12.5mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Zosaar Hct 50/12.5mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take the tablet at about the same time each day, with or without food. Do not stop taking it suddenly without your doctor’s advice, even if you feel well.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or light-headedness
  • Increased urination
  • Headache
  • Nausea or vomiting
  • Muscle cramps or weakness
  • Sensitivity to sunlight

Contraindications

  • Known hypersensitivity to losartan or hydrochlorothiazide, or to sulfonamide-derived medicines, or any ingredient in the tablet
  • Pregnancy – ARBs can cause harm to the developing baby and should be stopped as soon as pregnancy is confirmed or planned
  • Severe kidney impairment or anuria (inability to pass urine)

Drug / Food Interactions

  • Potassium supplements and potassium-sparing diuretics can raise blood potassium to unsafe levels when combined with losartan.
  • NSAIDs (such as ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function when combined with losartan or the diuretic component.
  • Lithium levels can rise when combined with losartan or thiazide diuretics, requiring closer monitoring.
  • Inform your doctor of all medicines you are taking, including over-the-counter and herbal products.

Quick Tips

  • Rise slowly from sitting or lying down, especially at the start of treatment, to avoid dizziness from a drop in blood pressure.
  • Attend scheduled blood tests to monitor kidney function and electrolytes as advised by your doctor.
  • Do not double the dose if you miss one; take it as soon as you remember unless it is almost time for the next dose.
  • Tell your doctor immediately if you become pregnant or are planning pregnancy while on this medicine.

Ingredients / Active Ingredients

  • Losartan potassium 50mg
  • Hydrochlorothiazide 12.5mg

Safety Advice

Pregnancy

No Data

There is no adequate data on use during pregnancy. Consult a doctor before use.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

ManufacturerAvo
ClassificationPrescription medicine
Ingredients / Active IngredientsHydrochlorothiazide
Pack Size30s
DosageThe usual dose is one tablet once daily, but the exact dose is individualised by the treating doctor based on blood pressure response and, when relevant, kidney function and blood electrolyte levels.
Shelf LifeRefer to the expiry date printed on the packaging.

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