Duopharma Glyprin 100mg Tablet

Duopharma Glyprin 100mg Tablet is an oral, enteric-coated tablet containing aspirin (acetylsalicylic acid) 100 mg as its active ingredient. It is manufactured by Duopharma, a Malaysian pharmaceutical company, and belongs to the salicylate class of medicines, specifically formulated at a low dose intended for long-term daily use rather than the higher 300-500 mg strengths used for pain and fever.

Glyprin 100mg is sold in Malaysia as an over-the-counter (OTC) product, available without a doctor’s prescription, though it is commonly started and monitored under medical guidance given its long-term use pattern. It is typically supplied in strips or bottles of 30 tablets, with the enteric coating designed to help the tablet pass through the stomach before dissolving in the intestine.

The enteric-coated formulation distinguishes Glyprin 100mg from plain, uncoated low-dose aspirin tablets, as the coating is intended to reduce direct contact between the tablet and the stomach lining during dissolution. This is a different formulation approach from combination cold/flu products that also contain aspirin at higher doses alongside other ingredients.

• Swallow the tablet whole with a full glass of water.
• Take the tablet preferably after a meal to help reduce stomach irritation.
• Do not crush, chew, or split the tablet, as this would damage the enteric coating and change how the tablet is absorbed.
• Take at the same time each day to build a consistent routine, as this product is typically used long-term.
• Check with a pharmacist before combining with any other product containing aspirin, ibuprofen, or other NSAIDs, to avoid duplicate salicylate or NSAID intake.

The typical adult dose is one 100 mg tablet once daily, or as otherwise directed by a doctor. This is a low-dose, long-term regimen rather than an as-needed dose, so consistency in daily timing is generally advised. If a dose is missed, take it as soon as remembered on the same day; if it is almost time for the next day’s dose, skip the missed dose and resume the normal schedule — do not double the dose. Do not stop this medicine abruptly without medical advice, as your doctor may want to review your ongoing treatment plan before any change.

Use before the expiry date printed on the strip or bottle and outer carton. Do not use tablets that have developed a strong vinegar-like smell, as this may indicate the aspirin has started to break down.

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep tablets in their original packaging until ready to take, and keep out of the reach and sight of children.

Aspirin

Acetylsalicylic Acid

• Known hypersensitivity to aspirin, other salicylates, or any other ingredient in the tablet.
• Active peptic ulcer disease or a history of gastrointestinal bleeding.
• Bleeding disorders or conditions causing an increased tendency to bleed.
• Severe, uncontrolled asthma with a known history of aspirin-induced bronchospasm.
• Children and adolescents under 16 years with a viral illness, due to the risk of Reye’s syndrome.
• Third trimester of pregnancy, unless specifically directed by a doctor.

• Other NSAIDs, such as ibuprofen or diclofenac, should not be combined with aspirin without medical advice, as this increases the risk of gastrointestinal bleeding.
• Anticoagulants such as warfarin, and other antiplatelet medicines such as clopidogrel, increase bleeding risk when combined with aspirin.
• Methotrexate levels can be increased by aspirin, raising the risk of methotrexate toxicity.
• Certain blood pressure medicines, including ACE inhibitors and diuretics, may have reduced effectiveness when taken alongside regular aspirin use.
• Alcohol should be limited, as it further increases the risk of stomach irritation and bleeding.

• Take the tablet at the same time each day to help maintain a consistent routine.
• Always take with food or after a meal.
• Never crush or chew the enteric-coated tablet.
• Check with a pharmacist before starting any new over-the-counter pain reliever while on this product.
• Inform any dentist or surgeon that you are taking daily aspirin before a procedure.
• Do not stop taking this medicine suddenly without discussing it with your doctor first.

Aspirin

Acetylsalicylic Acid

Precautions: Avoid use in the third trimester of pregnancy unless specifically directed by a doctor, and discuss use in early pregnancy or while breastfeeding with a healthcare professional. Use with caution in elderly patients, those with kidney or liver impairment, and those with a history of gout, as aspirin can affect uric acid levels. Inform your dentist or surgeon that you take daily aspirin before any planned procedure, as it may need to be paused beforehand.

When to See a Doctor or Pharmacist: Seek urgent medical attention if you notice black or tarry stools, vomiting blood, unusual bruising, or signs of an allergic reaction such as wheezing or facial swelling. Speak with your doctor before stopping this medicine, and before starting or stopping any other medicine while on daily aspirin.