Apo-Allopurinol 300mg Tablet

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Brand Apotex
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Overview

Apo-Allopurinol 300mg Tablet is a prescription-only medicine (POM) that contains Allopurinol 300mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Apo-Allopurinol 300mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Apo-Allopurinol 300mg Tablet after food to reduce stomach upset, with a full glass of water. Drink plenty of fluids throughout the day, especially when starting treatment, to help prevent kidney stones. Continue taking this medicine regularly even during a gout attack, unless your doctor advises otherwise.

Dosage

The usual starting dose of Apo-Allopurinol 300mg Tablet is typically 100mg daily, increased gradually by your doctor based on your blood uric acid levels, up to a maintenance dose that may range from 100mg to 300mg or more daily. Your doctor will determine the right dose for you based on regular blood tests.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Skin rash or itching
  • Nausea or vomiting
  • Diarrhoea
  • Drowsiness or dizziness
  • Headache
  • Mild joint pain
  • Change in taste

Contraindications

  • Known hypersensitivity to allopurinol or any ingredient in this product
  • Starting this medicine during an acute gout attack (may worsen or prolong the attack if started without cover)
  • Severe kidney impairment without dose adjustment

Drug / Food Interactions

  • Azathioprine and 6-mercaptopurine levels can rise dangerously high when combined with allopurinol, requiring dose reduction
  • ACE inhibitors and thiazide diuretics may increase the risk of allergic skin reactions when combined
  • Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring
  • Alcohol may increase uric acid levels and reduce the effectiveness of treatment

Quick Tips

  • Take after meals to reduce stomach upset
  • Drink plenty of water each day to help prevent kidney stones
  • Do not stop this medicine during a gout attack unless your doctor advises otherwise – it is a long-term preventive treatment, not a painkiller
  • Report any new skin rash to your doctor promptly, as this can occasionally be serious

Ingredients / Active Ingredients

  • Allopurinol 300mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandApotex
ClassificationPrescription medicine
Ingredients / Active IngredientsAllopurinol
Pack Size10s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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