Do I need a prescription to buy Progyluton Tablet?

No. Progyluton Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Progyluton Tablet contain?

Progyluton Tablet is a tablet containing Estradiol valerate. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Progyluton Tablet come in?

It is supplied in a pack size of 21s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Progyluton Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Progyluton Tablet?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Progyluton Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

What should I do if I notice side effects after using Progyluton Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Progyluton Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Progyluton Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Progyluton Tablet | estradiol valerate norgestrel | menopause HRT hormone tablet | DoctorOnCall Malaysia

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Progyluton Tablet

Brand Bayer

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: October 30, 2026

Overview

Progyluton Tablet contains Estradiol valerate and is presented as a tablet. It is supplied in a pack size of 21s.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Progyluton Tablet must only be used under the direction of a doctor following an online or in-clinic consultation with DoctorOnCall. Tablets are taken once daily at approximately the same time each day, in the order printed on the calendar pack, starting with the white (oestrogen-only) tablets followed by the light brown (combined) tablets. After completing all 21 tablets, a 7-day tablet-free interval is observed before starting the next pack, during which a withdrawal bleed similar to a period usually occurs.

Dosage

The typical regimen is one tablet daily for 21 consecutive days (11 white tablets followed by 10 light brown tablets), followed by a 7-day break with no tablets, then the cycle is repeated. Your doctor will determine the most appropriate starting point and duration of treatment based on your symptoms, medical history, and response, and treatment is generally reviewed periodically to confirm the lowest effective dose is being used for the shortest necessary duration.

Storage Instructions

Store Progyluton Tablet below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep the tablets in their original calendar pack until they are due to be taken so the correct sequence is followed.

Side Effects

Nausea or vomiting
Breast tenderness or swelling
Headache or migraine
Bloating
Mood changes
Spotting or breakthrough bleeding
Increased risk of blood clots with long-term use

Contraindications

Known, past, or suspected breast cancer
Known or suspected oestrogen-dependent cancer, such as endometrial cancer
Undiagnosed abnormal vaginal bleeding
Current or past history of venous thromboembolism (deep vein thrombosis or pulmonary embolism)
Active or recent arterial thromboembolic disease, such as stroke or heart attack
Severe liver disease or liver tumour
Pregnancy or suspected pregnancy
Known hypersensitivity to estradiol, norgestrel, or any tablet ingredient

Drug / Food Interactions

Enzyme-inducing medicines such as rifampicin, phenytoin, carbamazepine, and St John’s Wort may reduce the effectiveness of Progyluton Tablet
Certain antibiotics and antifungals may alter hormone levels when taken together
May affect the required dose of thyroid replacement therapy
Can influence blood clotting parameters in patients taking anticoagulants
Grapefruit juice may increase estradiol levels in some individuals

Quick Tips

Take each tablet in the exact order printed on the calendar pack to maintain the correct hormone sequence
Take your tablet at the same time every day to help you remember and maintain steady hormone levels
Attend scheduled follow-up reviews with your doctor to reassess whether continued HRT is appropriate
Report any unexpected vaginal bleeding, breast changes, or leg swelling to your doctor promptly
Do not share this medicine with anyone else, even if they have similar menopausal symptoms

Ingredients / Active Ingredients

Oestradiol

Estradiol valerate
Norgestrel
Lactose monohydrate
Maize starch
Povidone
Magnesium stearate
Talc
Colouring agents (tablet coating)

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Because Progyluton Tablet is a systemic hormone therapy, DoctorOnCall’s doctors will review your personal and family medical history, including any history of blood clots, cancer, liver disease, or cardiovascular disease, before prescribing. HRT is generally recommended at the lowest effective dose for the shortest duration needed to control symptoms, with periodic reassessment, and it is not intended as a contraceptive.

Frequently Asked Questions

Product Specifications

Brand	Bayer
Classification	Prescription medicine
Ingredients / Active Ingredients	Oestradiol
Pack Size	21s
Shelf Life	Progyluton Tablet is typically stable for up to the expiry date printed on the pack when stored under the manufacturer’s recommended conditions and left unopened. Do not use the medicine after the expiry date has passed.