It is unsafe to consume alcohol with Janumet XR 100/1000mg Tablet. Alcohol intoxication can increase the risk of lactic acidosis particularly in case of fasting, malnutrition or hepatic impairment.It is unsafe to consume alcohol with Janumet XR 100/1000mg Tablet. Alcohol can affect the blood sugar level therefore either hyperglycemia or hypoglycemia can occur. Furthermore, it can affect the pancreas which is the site of insulin production, which in turn worsen the diabetic control.
Janumet XR 100/1000mg Tablet should be safe to use during pregnancy because either animal or human studies have not shown any adverse effects on the fetus, however, uncontrolled hyperglycemia in people with PCOS can increase the risk of congenital abnormalities and intrauterine death. Animal studies have shown the toxic effects at high doses on the foetuses. Due to the lack of human data, it is not recommended to use during pregnancy. Thus, please consult your doctor for more details.
Breastfeeding Warning(Limited Data)
Limited human studies suggest that Janumet XR 100/1000mg Tablet does not represent a significant risk to the baby when used during pregnancy. In regards to limited data, please consult your doctor to decide on discontinuation of breastfeeding or Janumet XR 100/1000mg Tablet.No academic reports explaining the use of Janumet XR 100/1000mg Tablet during human lactation are available at the moment. Hence it is recommended to not use during breastfeeding.
Driving Warning (Safe)
Janumet XR 100/1000mg Tablet usually does not affect the ability to drive. Do not drive unless you are feeling well.Janumet XR 100/1000mg Tablet usually does not affect the ability to drive. Do not drive unless you are feeling well.
Kidney Warning(High Risk)
Janumet XR 100/1000mg Tablet is not recommended in patients with severe kidney disease, especially in patients with creatinine clearance less than 60mL/min. Patients with severe kidney disease has high risk to get lactic acidosis. Dose adjustment of Janumet XR 100/1000mg Tablet and regular check up to monitor renal function may be needed. Please consult your doctor before consumption.No dose adjustment is needed for mild renal impairment patients. However, if the glomerular filtration rate is lower than 60 mL/min, dose adjustment may be needed. Please consult your doctor.
Liver Warning(Limited information)
Janumet XR 100/1000mg Tablet should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Hence liver function test should be done before initiating Janumet XR 100/1000mg Tablet. Discontinuation of Janumet XR 100/1000mg Tablet may be needed if there is deterioration of liver function. Please consult your doctor. No dose adjustments needed in mild to moderate liver impairment whereas there are no studies on Janumet XR 100/1000mg Tablet use in severe liver impairment. However, Janumet XR 100/1000mg Tablet is primarily eliminated in the kidneys, so it is effects on severe liver impairment are expected to be safe.
As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.
Janumet XR 100/1000mg Tablet is a biguanide, works by inhibiting the production of glucose in the liver through the process of gluconeogenesis and glycogenesis, delaying absorption of glucose in the intestine and increases target cell insulin sensitivity. One of the symptoms experienced by PCOS includes insulin resistance, characterised by hyperglycemia.
Janumet XR 100/1000mg Tablet is a dipeptidyl peptidase 4 (DPP-4) inhibitor which will prolong active incretin levels. Incretin helps to regulate glucose homeostasis by increasing insulin synthesis and decreasing glucagon secretion. This will reduce the HbA1c level
Information last updated on: : Thu Nov 26 2020 03:46:13 GMT+0000 (Coordinated Universal Time) 5.0
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The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.
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Janumet XR 100/1000mg Tablet is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.
Janumet XR 100/1000mg Tablet is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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