Upha Glucoxit 500mg Tablet

Oral tablet containing metformin hydrochloride, with pharmacist guidance for safe and appropriate use.

  • Fast Delivery
  • Muslim-Friendly
  • FDA Approved
  • Secure Payment
Save: RM0.22   15% OFF
🎟️ Available Vouchers
OCT21
RM21 OFF
Min Spend RM550.00
Valid till: 27 Oct 2026
OCT14
RM14 OFF
Min Spend RM380.00
Valid till: 27 Oct 2026
OCT7
RM7 OFF
Min Spend RM200.00
Valid till: 27 Oct 2026

Click a voucher to copy the code. Automatically applied at checkout if conditions are met.

Have questions? Chat with us on WhatsApp
Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Key Information

What is Upha Glucoxit 500mg Tablet?

What is Upha Glucoxit 500mg Tablet?

  • Upha Glucoxit 500mg Tablet contains metformin hydrochloride 500mg per tablet, an oral medicine belonging to the biguanide class.
  • Metformin affects how the body handles glucose and responds to insulin. Its effects and suitability vary according to an individual's medical condition and treatment plan.
  • The tablet is manufactured by Duopharma and is listed on DoctorOnCall Malaysia in a 10-tablet pack.
  • Check the product packaging and accompanying leaflet for the active ingredient, strength, registration details and instructions. Consult your pharmacist or doctor if any information is unclear.
Is this strength right for me?

Is this strength right for me?

  • Upha Glucoxit is available in a 500mg tablet strength. The appropriate dose depends on your individual circumstances, kidney function, other medicines and the directions provided by your treating healthcare professional.
  • The tablet is generally taken with or immediately after meals, according to the directions provided by your healthcare professional. Swallow it with water and follow the product-specific instructions.
  • Do not start taking metformin without confirming that it is appropriate for you, particularly if you have kidney or liver problems, a history of metabolic acidosis, severe heart problems or a condition that may cause dehydration.
  • Tell your pharmacist or doctor if you are pregnant, planning a pregnancy or breastfeeding, or if you have any allergies or ongoing medical conditions.
  • If you are unsure whether this strength or product is appropriate for you, seek advice from our pharmacist or doctor before placing an order.
Delivery, packaging and ordering

Delivery, packaging and ordering

  • Select Upha Glucoxit 500mg Tablet and the available pack size on DoctorOnCall Malaysia, then review the product details before proceeding with your order.
  • If you need clarification about the product, your current medicines or the directions provided by your healthcare professional, contact a pharmacist before ordering.
  • DoctorOnCall lists delivery options for this product. Delivery availability and charges depend on your location and the applicable order and delivery terms.
  • Orders are subject to the pharmacy's applicable dispensing and verification procedures. Confirm the product's current supply classification with the pharmacy before publication of any statement about prescription requirements.
  • When your parcel arrives, check the product name, strength, packaging integrity, batch details and expiry date before taking the tablets.
Side effects, safety and when to seek help

Side effects, safety and when to seek help

  • Possible side effects of metformin include nausea, vomiting, diarrhoea, abdominal discomfort and changes in taste. These effects may vary between individuals and can be more noticeable when treatment begins.
  • Taking the tablet with meals, when directed, may help reduce gastrointestinal discomfort. Contact your pharmacist or doctor if side effects persist or interfere with your daily activities.
  • Metformin can rarely cause a serious condition called lactic acidosis, in which lactic acid builds up in the blood. The risk is higher in certain circumstances, including severe kidney impairment, dehydration, serious infection and excessive alcohol consumption.
  • Seek emergency medical attention if you experience unusual muscle cramps, severe weakness or tiredness, abdominal pain with vomiting, or difficulty breathing, particularly if several symptoms occur together.

How to take your Upha Glucoxit Tablet

  1. Step 1

    Check the instructions. Read the package leaflet and confirm your directions with your pharmacist or doctor. Make sure they know about your medical conditions, allergies and other medicines.

  2. Step 2

    Follow the recommended directions. Take the tablet according to the instructions provided by your treating healthcare professional. Do not change the amount or timing on your own.

  3. Step 3

    Take with food when directed. Metformin is commonly taken with or immediately after meals to reduce stomach discomfort. Swallow the tablet with water and follow the product-specific instructions.

  4. Step 4

    Monitor your condition. Attend recommended appointments for kidney-function checks and other monitoring. If you become seriously unwell or develop symptoms that may indicate lactic acidosis, seek urgent medical assessment.

Delivery & Returns

  • Malaysia-wide delivery
  • No prescription needed
  • Licensed pharmacy
  • Doctor consultation

If your order arrives damaged

  • Do not take Upha Glucoxit 500mg Tablet if the packaging is damaged, the blister strip is torn or opened, or the product appears to have been tampered with.
  • Check the carton and blister strip for signs of damage before taking the tablets.
  • Contact us on WhatsApp promptly and provide photographs of the outer packaging and affected product.
  • We will review the issue and arrange a replacement at no extra cost if the delivery issue is verified, in accordance with the applicable returns policy.

Returns policy

For safety and medicine-handling reasons, Upha Glucoxit 500mg Tablet cannot be returned or exchanged once it has left our pharmacy, except in cases involving a verified delivery issue, such as damaged packaging, an incorrect item or a missing item.

If there is a problem with your order, contact us within 24 hours of delivery so we can review the issue and advise you on the next steps.

Chat with us on WhatsApp

Dosage

Dosage is individualised by the prescribing doctor based on blood sugar control, kidney function, and response to treatment, usually starting at a low dose and gradually increased to reduce gastrointestinal side effects. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should never be self-adjusted or shared with another person.

Shelf Life

Upha Glucoxit 500mg Tablet is generally stable for up to 36 months from the date of manufacture when stored correctly and left unopened. Always check the expiry date printed on the blister strip or carton before use and do not use expired tablets.

Storage Instructions

Do

  • Store the tablets in a dry place below 30°C.
  • Protect the product from light and keep it in its original packaging.
  • Keep the tablets out of reach of children.
  • Check the expiry date and batch details on the packaging.
  • Follow any additional storage instructions printed on the carton or leaflet.

Don't

  • Don’t expose the tablets to excessive heat or moisture.
  • Don’t transfer tablets into unlabelled containers.
  • Don’t take the tablets after the expiry date.
  • Don’t share your medicine with another person.
  • Don’t dispose of unwanted tablets in household drains. Ask your pharmacist about appropriate medicine disposal.

Side Effects

Upha Glucoxit 500mg Tablet may cause digestive symptoms and other reactions in some people. These effects may vary between individuals, and some may require medical assessment, particularly during long-term treatment or in people with underlying health conditions.

Nausea and Vomiting

Nausea, vomiting or stomach discomfort may occur, particularly when treatment is first started.

Diarrhoea

Loose stools or diarrhoea may occur, especially during the initial stages of treatment.

Loss of Appetite

Some people may notice a reduced appetite or less interest in food.

Metallic Taste

A metallic taste in the mouth may develop during treatment.

Vitamin B12 Deficiency

Long-term use of metformin may reduce vitamin B12 levels. A deficiency may contribute to tiredness, anaemia or tingling and numbness, and monitoring may be appropriate for some patients.

Serious Warning: Lactic Acidosis

Lactic acidosis is a rare but potentially life-threatening complication associated with metformin. The risk may be higher in people with significant kidney impairment and certain conditions affecting liver function or causing reduced oxygen supply to the body.

Seek emergency medical attention if you experience warning signs such as:

  • Severe or unusual weakness.
  • Difficulty breathing or unusually deep, rapid breathing.
  • Persistent vomiting or abdominal pain accompanied by feeling very unwell.
  • Unusual drowsiness, dizziness or feeling cold with worsening symptoms.

If lactic acidosis is suspected, seek emergency care immediately rather than waiting for symptoms to improve.

This information does not replace the product leaflet or advice from a healthcare professional. Consult your doctor if side effects persist, worsen or cause concern. Do not change your dose or stop treatment without appropriate medical advice.

Contraindications

  • Severe kidney impairment or significantly reduced kidney function
  • Acute or unstable conditions that may affect kidney function, such as severe dehydration or shock
  • Known hypersensitivity to metformin
  • Severe liver disease
  • Conditions causing tissue hypoxia, such as severe heart or respiratory failure
  • Should be temporarily stopped before procedures involving iodinated contrast dye, as advised by a doctor

Drug / Food Interactions

  • Alcohol should be avoided or limited, as it increases the risk of lactic acidosis and low blood sugar
  • Certain diuretics, corticosteroids, and other medicines that raise blood sugar may reduce metformin’s effectiveness
  • Iodinated contrast media used in some imaging procedures may temporarily affect kidney function and increase lactic acidosis risk
  • Other diabetes medicines or insulin may increase the risk of low blood sugar when combined
  • Certain medicines that affect kidney elimination, such as some antibiotics, may alter metformin levels in the body

Quick Tips

  • Take this medicine exactly as prescribed and attend all scheduled follow-up appointments for blood sugar and kidney function monitoring
  • Take with food to reduce stomach upset, especially when starting treatment
  • Inform your doctor before any surgery, contrast dye imaging scan, or if you become severely unwell or dehydrated
  • Watch for signs of lactic acidosis such as unusual muscle pain, difficulty breathing, or severe tiredness, and seek urgent medical attention if these occur
  • Continue diet and lifestyle measures recommended by your doctor alongside this medicine for best blood sugar control

Ingredients / Active Ingredients

  • Metformin hydrochloride 500mg
  • Povidone
  • Microcrystalline cellulose
  • Magnesium stearate
  • Hypromellose (film coating)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Metformin remains one of the most established and widely prescribed first-line treatments for type 2 diabetes worldwide, valued for its effectiveness and low risk of causing hypoglycaemia when used alone. Because ongoing kidney function monitoring and periodic review of blood sugar control are essential, Upha Glucoxit is dispensed by DoctorOnCall only after a doctor’s assessment, with regular follow-up recommended throughout treatment for patients in Malaysia and Singapore.

How to buy

Go to the DoctorOnCall website

Go to the DoctorOnCall website

Visit DoctorOnCall Malaysia, search for Upha Glucoxit 500mg Tablet and select the available pack size.

Place your order

Place your order

Review the product details, enter your delivery information and proceed through the available checkout and payment options. Confirm any applicable dispensing requirements with the pharmacy before completing your order.

Pharmacist review and dispensing

Pharmacist review and dispensing

The pharmacy reviews the order and confirms the applicable dispensing requirements before preparing it. A registered pharmacist can clarify product information, directions and relevant safety precautions.

Receive your order

Receive your order

Your order is packed for delivery to your address. Delivery options and timing depend on your location and the applicable delivery terms. Check the packaging, tablet strength and expiry date when the parcel arrives before taking the tablets.

Frequently Asked Questions

Product Specifications

BrandUpha Glucoxit
ClassificationNon-prescription
Ingredients / Active IngredientsMetformin
Pack Size10s
ManufacturerDuopharma (M) Sdn. Bhd.
Strength500mg per tablet
DosageRefer to the product packaging and package leaflet for directions on use.
Shelf LifeRefer to the expiry date printed on the blister strip or carton. Confirm the manufacturer's stated shelf-life period from the current product packaging.
Pack Contents10 tablets, subject to the selected pack option
Registration HolderDuopharma (M) Sdn. Bhd.
FormTablet
RouteOral
StorageStore in a dry place below 30°C, protect from light and keep out of reach of children.
ExcipientsPovidone, microcrystalline cellulose, magnesium stearate and hypromellose film coating, according to available product information. Refer to the current package insert for the complete formulation.

Customer Reviews

4.3 · 10 reviews
  • Verified purchase

    Aisyah · Purchased: Upha Glucoxit 500mg Tablet 10s (strip)

    fast delivery and affordable prices

  • Verified purchase

    Kavitha a/p Subramaniam · Purchased: Upha Glucoxit 500mg Tablet

    Simple ordering flow and clear product listing. Mudah digunakan.

  • Verified purchase

    Ameera Natasya · Purchased: Upha Glucoxit 500mg Tablet 10s (strip) x 10

    First time order sini, quite easy actually. Will order again

  • Verified purchase

    Farah Nadia · Purchased: Upha Glucoxit 500mg Tablet

    Overall website experience was good. Proses pesanan pun mudah nice nice

Confirm Action
×

Are you sure?

×

Pharmacist Screening

×

What condition or symptom are you treating with this medication?

*Please select the closest match. A pharmacist may call to verify your selection before dispensing.

Important Medical Information

💊 Recommended Dosage:

Dosage is individualised by the prescribing doctor based on blood sugar control, kidney function, and response to treatment, usually starting at a low dose and gradually increased to reduce gastrointestinal side effects. This medicine requires a valid prescription obtained through an online consultation with a doctor via DoctorOnCall, and should never be self-adjusted or shared with another person.

🛑 Contraindications (Do not use if):
  • Severe kidney impairment or significantly reduced kidney function
  • Acute or unstable conditions that may affect kidney function, such as severe dehydration or shock
  • Known hypersensitivity to metformin
  • Severe liver disease
  • Conditions causing tissue hypoxia, such as severe heart or respiratory failure
  • Should be temporarily stopped before procedures involving iodinated contrast dye, as advised by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.