Trajenta Duo 2.5/500mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Trajenta Duo 2.5/500mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Linagliptin 2.5mg and Metformin hydrochloride 500mgmg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take the tablet with meals, morning and evening, to reduce the chance of stomach upset from the metformin component.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to linagliptin, metformin, or any excipient
  • Severe kidney impairment or acute conditions that may alter kidney function (severe dehydration, severe infection, shock)
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions associated with tissue hypoxia, such as heart or respiratory failure

Drug / Food Interactions

  • Combining with insulin or sulfonylureas (such as gliclazide) increases the risk of low blood sugar; a lower dose of the other medicine may be needed.
  • Iodinated contrast media used in some imaging scans may temporarily need metformin to be paused – inform the radiology team you are taking this medicine.
  • Excess alcohol intake increases the risk of a rare but serious condition called lactic acidosis with metformin.
  • Inform your doctor of all medicines you are taking, including other diabetes treatments.

Quick Tips

  • Take the tablet with food to reduce stomach upset.
  • Recognise the signs of low blood sugar (shakiness, sweating, confusion) if you are also taking insulin or a sulfonylurea, and carry a fast-acting sugar source.
  • Inform your doctor before any scan involving contrast dye, as metformin may need to be temporarily stopped.
  • Attend scheduled blood tests to monitor kidney function and blood sugar control.

Ingredients / Active Ingredients

  • Linagliptin 2.5mg
  • Metformin hydrochloride 500mgmg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandBoehringer Ingelheim
ManufacturerBoehringer Ingelheim
ClassificationPrescription medicine
Ingredients / Active IngredientsMetformin
Pack Size60s
DosageThe usual dose is one 2.5/500mgmg tablet taken twice daily, morning and evening, with meals. Your doctor will individualise the exact strength based on your current metformin dose and blood sugar control.
Shelf LifeRefer to the expiry date printed on the packaging.

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Important Medical Information

💊 Recommended Dosage:

The usual dose is one 2.5/500mgmg tablet taken twice daily, morning and evening, with meals. Your doctor will individualise the exact strength based on your current metformin dose and blood sugar control.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to linagliptin, metformin, or any excipient
  • Severe kidney impairment or acute conditions that may alter kidney function (severe dehydration, severe infection, shock)
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Severe liver impairment
  • Conditions associated with tissue hypoxia, such as heart or respiratory failure
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.