Trajenta Duo 2.5/500mg Tablet
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Prescription Required
Overview
Trajenta Duo 2.5/500mgmg Tablet combines linagliptin, a DPP-4 inhibitor, with metformin, and is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Linagliptin increases levels of incretin hormones that help the pancreas release insulin appropriately after meals, while metformin reduces glucose production by the liver and improves the body’s sensitivity to insulin.
How it Works
Linagliptin blocks the DPP-4 enzyme, which normally breaks down incretin hormones. This raises incretin levels, which stimulates the pancreas to release insulin after meals and suppresses excess glucose release by the liver, in a glucose-dependent manner. Metformin reduces glucose production in the liver and increases how effectively the body’s tissues use insulin.
Directions for Use
Take the tablet with meals, morning and evening, to reduce the chance of stomach upset from the metformin component.
Dosage
The usual dose is one 2.5/500mgmg tablet taken twice daily, morning and evening, with meals. Your doctor will individualise the exact strength based on your current metformin dose and blood sugar control.
Shelf Life
Refer to the expiry date printed on the packaging.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Nausea or vomiting
- Diarrhea
- Stomach discomfort or cramps
- Metallic taste in the mouth
- Loss of appetite
- Weight loss (in some cases)
Contraindications
- Known hypersensitivity to linagliptin, metformin, or any excipient
- Severe kidney impairment or acute conditions that may alter kidney function (severe dehydration, severe infection, shock)
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis
- Severe liver impairment
- Conditions associated with tissue hypoxia, such as heart or respiratory failure
Drug / Food Interactions
- Combining with insulin or sulfonylureas (such as gliclazide) increases the risk of low blood sugar; a lower dose of the other medicine may be needed.
- Iodinated contrast media used in some imaging scans may temporarily need metformin to be paused – inform the radiology team you are taking this medicine.
- Excess alcohol intake increases the risk of a rare but serious condition called lactic acidosis with metformin.
- Inform your doctor of all medicines you are taking, including other diabetes treatments.
Quick Tips
- Take the tablet with food to reduce stomach upset.
- Recognise the signs of low blood sugar (shakiness, sweating, confusion) if you are also taking insulin or a sulfonylurea, and carry a fast-acting sugar source.
- Inform your doctor before any scan involving contrast dye, as metformin may need to be temporarily stopped.
- Attend scheduled blood tests to monitor kidney function and blood sugar control.
Frequently Asked Questions
What is Trajenta Duo used for?
Trajenta Duo combines linagliptin and metformin and is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
How does Trajenta Duo work?
Linagliptin raises incretin hormone levels to help release insulin after meals, while metformin reduces glucose production by the liver and improves insulin sensitivity.
Can this medicine cause low blood sugar on its own?
The linagliptin component has a low risk on its own, but combining it with insulin or a sulfonylurea increases the risk of low blood sugar.
Do I still need to follow a diet and exercise plan on this medicine?
Yes, this medicine works best alongside a healthy diet and regular physical activity, not as a replacement for them.
Can I stop taking this medicine once my blood sugar improves?
No, do not stop without checking with your doctor – type 2 diabetes usually requires ongoing treatment even when blood sugar levels improve.
What should I do if I notice symptoms of low blood sugar?
Take a fast-acting source of sugar immediately (such as glucose tablets or sweet juice) and inform your doctor if this happens often.
Why might I get an upset stomach with this medicine?
The metformin component can cause nausea or diarrhoea, especially when starting treatment – taking it with meals can help reduce this.
Can I buy Trajenta Duo 2.5/500mg Tablet from DoctorOnCall?
Yes, Trajenta Duo 2.5/500mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Trajenta Duo 2.5/500mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Trajenta Duo 2.5/500mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Trajenta Duo 2.5/500mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Trajenta Duo 2.5/500mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Trajenta Duo 2.5/500mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Linagliptin 2.5mg
- Metformin hydrochloride 500mgmg
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
