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Jardiance Duo 12.5/500mg Tablet 60s - DoctorOnCall Online Pharmacy

Jardiance Duo 12.5/500mg Tablet 60s

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Don’t Have A Prescription? Get A Consult With Our Doctor Today.
STEP 1
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STEP 2
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STEP 3
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Term & Condition
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We ensure that all our pharmaceutical products including health supplements and traditional preparations are registered with the National Pharmaceutical Regulatory Authority (NPRA) Malaysia
Free Delivery on orders above RM120
Enjoy free delivery with a minimum spend of RM120 on our platform.

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Jardiance Duo 12.5/500mg Tablet 60s - DoctorOnCall Online Pharmacy

Jardiance Duo 12.5/500mg Tablet 60s

RM 207.68

Product Overview

Introduction of Jardiance Duo 12.5/500mg Tablet 60s

Jardiance Duo 12.5/500mg Tablet

Introduction to Jardiance Duo 12.5/500mg Tablet
Jardiance Duo 12.5/500mg Tablet is a combination prescription medication belonging to two drug classes — an SGLT-2 inhibitor and a biguanide — working together in a single convenient tablet. It contains two active ingredients: Empagliflozin 12.5mg and Metformin Hydrochloride 500mg, both of which are well-established pharmaceutical compounds widely recognised in modern diabetes management. Like most medications, it does come with some side effects you should be aware of, including nausea, urinary tract infections, low blood sugar (hypoglycaemia), and genital yeast infections — so it's always important to take this medicine exactly as your doctor has prescribed. If you're considering this tablet, you'll want to know that it requires a valid prescription, should be taken with meals to reduce stomach discomfort, and must be stored correctly to maintain its effectiveness. We're here to make sure you have all the right information before you make your purchase, so you feel confident and safe every step of the way.

How to Take Jardiance Duo 12.5/500mg Tablet
Jardiance Duo 12.5/500mg Tablet should be taken orally with meals, typically twice daily, to help minimise gastrointestinal side effects such as nausea or stomach upset. Swallow the tablet whole with a glass of water — do not crush, chew, or split the tablet unless your healthcare provider has specifically advised otherwise. Always follow your doctor's or pharmacist's instructions carefully regarding the timing and frequency of your doses, and never adjust your dosage on your own without professional medical guidance.

Dosage of Jardiance Duo 12.5/500mg Tablet
The typical recommended dose of Jardiance Duo 12.5/500mg is one tablet taken twice daily with meals, though your doctor may adjust the dosage based on your individual kidney function, blood sugar levels, and overall health condition. Always adhere to the prescribed dosage and do not exceed the recommended amount without direct medical supervision.

Shelf Life of Jardiance Duo 12.5/500mg Tablet
Jardiance Duo 12.5/500mg Tablet generally has a shelf life of 2 to 3 years from the date of manufacture, as indicated on the original packaging. Always check the expiry date printed on the blister pack or carton before use, and never consume the tablet if it has passed its expiry date. Using expired medication may reduce its effectiveness and could potentially pose health risks.

How to Store Jardiance Duo 12.5/500mg Tablet

  • Store at room temperature below 30°C, away from direct sunlight, heat, and moisture.
  • Keep the tablets in their original blister packaging until you are ready to take them.
  • Do not store in the bathroom, near the kitchen sink, or in any area with high humidity.
  • Keep this medication out of reach of children and pets at all times.
  • If you notice any change in the tablet's colour, texture, or smell, do not use it and consult your pharmacist.
  • Do not freeze this medication.

Active Ingredient of Jardiance Duo 12.5/500mg Tablet

  • Jardiance Duo 12.5/500mg Tablet contains the following two active pharmaceutical ingredients (APIs):
  • Active Ingredient
  • Strength
  • Drug Class
  • Empagliflozin
  • 12.5 mg
  • SGLT-2 Inhibitor
  • Metformin Hydrochloride
  • 500 mg
  • Biguanide (Antidiabetic)

Empagliflozin works by blocking the SGLT-2 receptor in the kidneys, helping the body eliminate excess glucose through urine. Metformin Hydrochloride is one of the most widely used antidiabetic agents globally, known for its role in reducing hepatic glucose production and improving insulin sensitivity. Together, these two compounds form a clinically recognised dual-action combination tablet.

Side Effects of Jardiance Duo 12.5/500mg Tablet
As with all prescription medications, Jardiance Duo 12.5/500mg may cause side effects in some individuals. Below is a list of known common and less common adverse reactions:

Common Side Effects:

  • Nausea, vomiting, or stomach upset
  • Diarrhoea or loose stools
  • Urinary tract infections (UTIs) — symptoms may include burning sensation during urination
  • Genital yeast infections (mycotic infections) in both men and women
  • Increased frequency of urination
  • Headache
  • Mild hypoglycaemia (low blood sugar), especially when combined with other antidiabetic agents

Less Common Side Effects:

  • Dizziness or lightheadedness
  • Dehydration or increased thirst
  • Decreased appetite
  • Metallic taste in the mouth (associated with Metformin)
  • Skin rash or itching
  • Urinary urgency

Serious but Rare Side Effects (Seek Immediate Medical Attention):

  • Lactic acidosis — a rare but serious condition associated with Metformin; symptoms include muscle pain, difficulty breathing, stomach discomfort, and feeling cold or dizzy
  • Diabetic ketoacidosis (DKA) — even with near-normal blood sugar levels; symptoms include nausea, vomiting, abdominal pain, fatigue, and difficulty breathing
  • Fournier's gangrene — a rare but severe genital infection requiring urgent medical care
  • Severe allergic reactions including swelling of the face, lips, or throat
  • Significant drop in blood pressure (hypotension)
  • Acute kidney injury

⚠️ This is not a complete list of all possible side effects. If you experience any unusual symptoms after taking this medication, please contact your doctor or pharmacist immediately.

Contraindications of Jardiance Duo 12.5/500mg Tablet
Jardiance Duo 12.5/500mg Tablet is not suitable for everyone. This medication should not be used in the following conditions:

  • Hypersensitivity to Empagliflozin, Metformin Hydrochloride, or any of the tablet's excipients
  • Patients with Type 1 Diabetes Mellitus
  • Patients with diabetic ketoacidosis (DKA)
  • Individuals with severe renal impairment (eGFR below 30 mL/min/1.73m²) or end-stage renal disease
  • Patients with hepatic impairment (liver disease)
  • Individuals with a history of or at risk of lactic acidosis
  • Patients with acute or chronic metabolic acidosis
  • Pregnant women, particularly in the second and third trimesters
  • Breastfeeding mothers (use is not recommended)
  • Patients scheduled for iodinated contrast imaging procedures — Metformin should be temporarily discontinued before and after such procedures
  • Patients with severe dehydration, excessive alcohol intake, or conditions causing tissue hypoxia (e.g., heart failure, respiratory failure)
  • Paediatric patients under 18 years of age (safety and efficacy not established for this combination)

Always inform your doctor of your full medical history, including all current medications, before starting Jardiance Duo.

Drug & Food Interactions of Jardiance Duo 12.5/500mg Tablet

Drug Interactions

  • Interacting Drug/Class
  • Potential Interaction
  • Insulin or insulin secretagogues (e.g., sulfonylureas)
  • Increased risk of hypoglycaemia; dose adjustment may be required
  • Diuretics (e.g., furosemide, hydrochlorothiazide)
  • May increase risk of dehydration and low blood pressure
  • ACE inhibitors / ARBs
  • Combined use may increase risk of hypotension and renal impairment
  • Corticosteroids
  • May reduce blood sugar-lowering effectiveness
  • Iodinated contrast agents
  • Risk of acute renal failure and lactic acidosis; Metformin should be paused
  • NSAIDs (e.g., ibuprofen, naproxen)
  • May impair kidney function, affecting Metformin elimination
  • Cationic drugs (e.g., cimetidine, digoxin, morphine)
  • May compete with Metformin for renal tubular transport, increasing plasma levels
  • Alcohol
  • Increases risk of lactic acidosis and hypoglycaemia; avoid excessive alcohol consumption
  • Rifampicin and other enzyme inducers
  • May reduce Empagliflozin plasma levels and effectiveness
  • Lithium
  • Metformin may affect lithium levels; monitor closely

Food Interactions

  • Alcohol: Excessive alcohol intake significantly increases the risk of lactic acidosis and should be avoided or strictly limited while on this medication.
  • High-carbohydrate meals: While not a direct drug-food interaction, large carbohydrate-rich meals may affect blood glucose control.
  • Grapefruit: No significant interaction has been established, but it is advisable to discuss your full diet with your healthcare provider.

Always inform your doctor or pharmacist about all prescription medicines, over-the-counter drugs, herbal supplements, and vitamins you are currently taking.

Quick Tips for Jardiance Duo 12.5/500mg Tablet

  • Always take this tablet with food to reduce the chance of stomach upset or nausea.
  • Never skip doses — if you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double up.
  • Stay well hydrated throughout the day, as this medication can increase urination and may lead to dehydration.
  • Monitor your blood sugar levels regularly as advised by your doctor to track how well the medication is working.
  • Carry a source of fast-acting sugar (e.g., glucose tablets or sweets) in case of hypoglycaemia symptoms.
  • Inform your dentist, surgeon, or any specialist that you are taking this medication before any medical procedure.
  • Do not stop taking this medication suddenly without consulting your doctor, as this may affect your blood sugar control.
  • Store your tablets in a cool, dry place away from sunlight and humidity — not in the bathroom cabinet.
  • Check the expiry date on the packaging every time before taking your medication.
  • Keep all follow-up appointments with your doctor for regular kidney function and blood sugar monitoring.
  • Do not share this medication with others, even if they appear to have similar symptoms — this is a prescription-only medicine.
  • Dispose of unused or expired tablets responsibly — return them to your pharmacist rather than throwing them in household waste.

FAQs – Jardiance Duo 12.5/500mg Tablet

Purchasing & Availability

Q1: Can I buy Jardiance Duo 12.5/500mg Tablet online in Malaysia?
Yes, you can purchase Jardiance Duo 12.5/500mg Tablet through our licensed online pharmacy in Malaysia. We are a registered pharmaceutical platform, and all medications sold on our website are sourced from authorised distributors to ensure authenticity and quality.

Q2: Is a prescription required to purchase Jardiance Duo 12.5/500mg Tablet in Malaysia?
Yes, absolutely. Jardiance Duo 12.5/500mg is a prescription-only medication (POM) in Malaysia. In compliance with Malaysian pharmaceutical regulations, you will need to provide a valid prescription from a registered medical practitioner before your order can be processed and dispensed.

Q3: How do I submit my prescription when ordering online?
It's easy! During the checkout process, you can upload a clear photo or scanned copy of your doctor's prescription. Our in-house pharmacist will review and verify it before your order is approved and dispatched. If you have any questions about the prescription submission process, our customer support team is happy to guide you.

Q4: Is the Jardiance Duo 12.5/500mg Tablet sold on your website authentic and registered?
Yes. All products available on our platform are sourced from authorised pharmaceutical distributors and are registered with the National Pharmaceutical Regulatory Agency (NPRA) Malaysia. You can verify the product registration status on the NPRA website for your peace of mind.

Q5: What is the price of Jardiance Duo 12.5/500mg Tablet in Malaysia?
Pricing may vary depending on pack size and current promotions. Please visit the product page on our website for the most up-to-date pricing in Malaysian Ringgit (MYR). We strive to offer competitive and transparent pricing with no hidden charges.

Delivery & Ordering

Q6: Do you deliver Jardiance Duo 12.5/500mg Tablet throughout Malaysia?
Yes! We offer nationwide delivery across Peninsular Malaysia, Sabah, and Sarawak. Delivery timelines and charges may vary depending on your location. Standard delivery typically takes 3 to 7 working days, while express options may be available for selected areas.

Q7: How is the medication packaged for delivery to ensure it arrives safely?
We take medication safety seriously. All orders are packed in discreet, secure packaging that protects the tablets from heat, moisture, and physical damage during transit. Temperature-sensitive medications are handled with appropriate care to maintain product integrity.

Q8: Can I track my order after it has been placed?
Yes! Once your order has been dispatched, you will receive a tracking number via email or SMS so you can monitor your delivery status in real time.

Q9: What should I do if my order arrives damaged or with an incorrect product?
Please contact our customer service team immediately upon receiving a damaged or incorrect order. We have a dedicated support process to resolve such issues promptly, including replacement or refund options where applicable.

Safety, Storage & Handling

Q10: How should I store Jardiance Duo 12.5/500mg Tablet after receiving my delivery?
Store the tablets at room temperature below 30°C, in a cool and dry place away from direct sunlight and moisture. Keep them in their original packaging and out of reach of children. Do not store them in the bathroom or near the kitchen sink.

Q11: What should I do if I accidentally take more than the prescribed dose?
If you suspect an overdose, seek immediate medical attention or contact the nearest emergency department. Do not attempt to self-manage a potential overdose situation. In Malaysia, you can also call the Poison Control Centre at Hospital Kuala Lumpur for guidance.

Q12: Can I return or exchange Jardiance Duo 12.5/500mg Tablet after purchase?
Due to the nature of pharmaceutical products and safety regulations in Malaysia, medications generally cannot be returned or exchanged once dispensed, unless there is a verified dispensing error or the product is found to be defective. Please review our return policy on the website or contact our pharmacist team for clarification.

Q13: How do I know if the Jardiance Duo tablet I received has not expired?
Always check the expiry date printed on the blister pack and outer carton upon receiving your order. Our pharmacy team ensures that all dispensed medications have a sufficient shelf life remaining at the time of dispatch. If you have any concerns about the expiry date of your received product, please contact us immediately.

Q14: Is it safe to order prescription medication online in Malaysia?
Yes, provided you are ordering from a licensed and registered online pharmacy that complies with the Poisons Act 1952 and guidelines set by the Ministry of Health Malaysia (MOH). Our platform operates in full compliance with Malaysian pharmaceutical laws, ensuring that your health and safety are always our top priority.

Frequently Bought Together

Brands

Boehringer Ingelheim

Active Ingredient

empagliflozin metformin 

Manufactured by

Boehringer Ingelheim

Side Effects

As with all medications, you may experience some side effects. Not everyone experiences it. This is not a cause for concern. However, it is so that you are aware of it.

Low Sugar Level, Weakness, Dizziness, Nausea, Thirst, Increased urinary output, Urinary tract infection, Generalized itch, Rash, Genital infection

Cough or hoarseness, Decreased appetite, Diarrhea, Dyspnea, Upper respiratory tract infection, Nausea, Vomiting, Flatulence, Heartburn/dyspepsia, Abdominal distention, Constipation.

Warning Precautions

Precautionary Steps of Jardiance Duo 12.5/500mg Tablet 60s

Please consult a doctor especially before taking Jardiance Duo 12.5 mg/500 mg FC tab. If you have any of the following conditions & contraindications:-
  • Allergy to Jardiance Duo 12.5 mg/500 mg FC tab or any of its components
  • Lactic acidosis
  • Diabetic ketoacidosis
  • Renal diseases 
  • Alcoholism 
  • Acute alcohol intoxication 
  • Hepatic insufficiency 
  • It is not recommended for children & Neonates. Please keep it out of reach from them
  • Hypersensitivity
  • Breastfeeding
  • Pregnancy 

Please stop using this medication if you are experiencing these symptoms and conditions.

 
Jardiance Duo 12.5 mg/500 mg FC tab Drug Interactions

Drug to drug interaction reaction of Jardiance Duo 12.5 mg/500 mg FC tab varies from a person to another person. It is advisable to check with your doctor about all the possible drug interactions before starting the medication.
  • Alcohol
  • Empagliflozin
  • thiazide & loop diuretics
  • Sulfonylureas
  • Gemfibrozil
  • rifampicin
  • Probenecid
  • Metformin
  • NSAIDs 
  • ACE inhibitors
  • angiotensin II receptor antagonists
  • cimetidine 

This is an incomprehensive list of drug-to-drug interactions and conditions that might interfere with Jardiance Duo 12.5 mg/500 mg FC tab function. Do inform your doctor about all your current medications prior to consuming this drug. 

Keep the following precautions in mind as well:-
  • Avoid excess exposure to sunlight
  • Avoid this medicine for a longer use
  • Alcohol might affect your liver if it is taken with this medication
  • Tell your doctor if you have any other diseases or if you are taking any other medication
  • Do not discontinue the prescribed course


Alcohol Warning (Not Advisable)

Alcohol may affect blood glucose levels in patients with diabetes. Jardiance Duo 12.5/500mg Tablet 60s might also increase the risk of diabetes ketoacidosis but this mostly applies to patients who abuse alcohol. Generally, it is not advisable to have alcohol with Jardiance Duo 12.5/500mg Tablet 60s.It is unsafe to consume alcohol with Jardiance Duo 12.5/500mg Tablet 60s. Alcohol intoxication can increase the risk of lactic acidosis particularly in case of fasting, malnutrition or hepatic impairment.

Pregnancy Warning (Not Safe)

Jardiance Duo 12.5/500mg Tablet 60s is not recommended to use during pregnancy. Animal studies have show an adverse effect on the foetus after birth however there are no human studies.Jardiance Duo 12.5/500mg Tablet 60s should be safe to use during pregnancy because either animal or human studies have not shown any adverse effects on the fetus, however, uncontrolled hyperglycemia in people with PCOS can increase the risk of congenital abnormalities and intrauterine death.

Breastfeeding Warning (Not Advisable)

Jardiance Duo 12.5/500mg Tablet 60s is not advisable to use during lactation. It is not known if Jardiance Duo 12.5/500mg Tablet 60s passes into human breast milk.Limited human studies suggest that Jardiance Duo 12.5/500mg Tablet 60s does not represent a significant risk to the baby when used during pregnancy. In regards to limited data, please consult your doctor to decide on discontinuation of breastfeeding or Jardiance Duo 12.5/500mg Tablet 60s.

Driving Warning (Generally Safe)

Jardiance Duo 12.5/500mg Tablet 60s usually does not affect the ability to drive. Do not drive unless you are feeling well.Jardiance Duo 12.5/500mg Tablet 60s usually does not affect the ability to drive. Do not drive unless you are feeling well.

Kidney Warning (High Risk)

Jardiance Duo 12.5/500mg Tablet 60s should be used with caution in patients with severe kidney disease as its main mechanism of action is at the kidney. Dose adjustment of Jardiance Duo 12.5/500mg Tablet 60s may be needed for patients with kidney disease. Please consult your doctor. However, the use of Jardiance Duo 12.5/500mg Tablet 60s is not allowed in patients with severe kidney disease.Jardiance Duo 12.5/500mg Tablet 60s is not recommended in patients with severe kidney disease, especially in patients with creatinine clearance less than 60mL/min. Patients with severe kidney disease has high risk to get lactic acidosis. Dose adjustment of Jardiance Duo 12.5/500mg Tablet 60s and regular check up to monitor renal function may be needed. Please consult your doctor before consumption.

Liver Warning (Use With Care)

Patients with liver disease may require a dose adjustment while on Jardiance Duo 12.5/500mg Tablet 60s. It is due to the prolonged exposure of Jardiance Duo 12.5/500mg Tablet 60s in patients with liver disease. Thus, patients with severe liver disease are not allowed to be on Jardiance Duo 12.5/500mg Tablet 60s.Jardiance Duo 12.5/500mg Tablet 60s should be used with caution in patients with liver disease due to increased risk of lactic acidosis. Hence liver function test should be done before initiating Jardiance Duo 12.5/500mg Tablet 60s. Discontinuation of Jardiance Duo 12.5/500mg Tablet 60s may be needed if there is deterioration of liver function. Please consult your doctor.

FAQ

Disclaimer

Information last updated on: Fri Apr 10 2026 04:08:17 GMT+0000 (Coordinated Universal Time) The product images shown are for illustration purposes only and may not be an exact representation of the product.

The content provided on this webpage is to provide information only, to be fully-interpreted by a medical professional, and not intended as a guide to make purchase decisions, or a substitute to advice of a medical professional. Effectiveness and side effects of medication may differ from individual to individual. We do not encourage any customer to self-diagnose and/or self-medicate. Patients should always consult a medical professional before taking or using any medication. The content provided here is non-exhaustive and may not cover all aspects of the medication. Our service should only be used to support the doctor-patient dynamic, not replace it.

The fulfilment of prescription medication is subject to our review of a prescription issued by a Malaysian Medical Council (MMC) registered doctor. If required, we will provide a tele-consult service with one of our registered panel doctors. This is not an advertisement of a medicine as such an advertisement would require prior approval from the Medicines Advertisement Board of Malaysia. Jardiance Duo 12.5/500mg Tablet 60s is available in many areas in Malaysia. Kuala Lumpur, Bukit Bintang, Titiwangsa, Setiawangsa, Wangsa Maju, Kepong, Segambut, Bandar Tun Razak, Cheras, Subang Jaya, Petaling Jaya, Mont Kiara, Puchong, Bandar Sunway, TTDI, Seri Kembangan, Klang, Bukit Tinggi, Damansara, Sentul, Penang, George Town, Jelutong, Gelugor, Bayan Baru, Bandar Baru Air Itam, Sungai Ara, Bukit Mertajam, Butterworth, Perai, Johor Bahru, Skudai, Bukit Indah, Gelang Patah, Senai, Pasir Gudang, Taman Daya, Taman Molek, Taman Perling, Tebrau, Danga Bay, Larkin, Nusajaya, Pontian, Masai, Setia Tropika, Desaru, Tampoi.


Jardiance Duo 12.5/500mg Tablet 60s is available at many places in Singapore. Ang Mo Kio, Alexandra, Admiralty, Bedok, Bishan, Bukit Batok, Bukit Merah, Bukit Panjang, Bukit Timah, Boat Quay, Buona Vista, Beach Road, Bugis, Balestier, Boon Lay, Central Area, Choa Chu Kang, Clementi, Chinatown, Commonwealt, City Hall, Clarke Quay, Changi Airport, Changi Village, Clementi Park, Dairy Farm, Eunos, East Coast, Farrer Park, Geylang, Hougang, Harbourfront, Holland, Jurong, Jurong East, Jurong West, Kallang/ Whampoa, Lim Chu Kang, Marine Parade, Marina, Macpherson, Mandai, Newton, Novena, Orchard, Pasir Ris, Punggol, Potong Pasir, Paya Lebar, Queenstown, Raffles Place, Rochor, River Valley, Sembawang, Sengkang, Serangoon, Serangoon Rd, Seletar, Tampines, Toa Payoh, Tanjong Pagar, Telok Blangah, Tanglin, Thomson, Tuas, Tengah, Upper East Coast, Upper Bukit Timah, Upper Thomson, Woodlands, West Coast, Yishun, Yio Chu Kang.
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