Progynova 1mg Tablet

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Overview

Progynova 1mg Tablet contains estradiol valerate 1mg, a lower-dose form of oestrogen used in hormone replacement therapy (HRT) to relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness, and it is commonly used either as a starting dose for women new to HRT or as a step-down dose for women whose symptoms are already well controlled on a higher strength. In women who still have their womb, Progynova 1mg Tablet is typically prescribed alongside a progestogen to protect the womb lining from unopposed oestrogen stimulation.

As Progynova 1mg Tablet is a prescription-only hormone medicine, it is supplied through DoctorOnCall only after an online consultation with a doctor, who will review your medical history, menopausal symptoms, and personal risk factors such as history of blood clots, breast cancer, or liver disease before confirming whether this lower starting dose is appropriate for you.

How it Works

Progynova 1mg Tablet works by replenishing the body’s oestrogen (specifically estradiol) at a lower dose than the 2mg strength, helping to reduce vasomotor symptoms such as hot flashes and night sweats and support vaginal tissue health, while allowing your doctor to find the lowest effective dose that controls your symptoms with the least hormonal exposure.

Directions for Use

Take Progynova 1mg Tablet exactly as prescribed by your doctor, usually one tablet daily at the same time each day, swallowed whole with water; your doctor will advise whether you are on a continuous or cyclic regimen, and if a progestogen is also prescribed, both medicines should be taken according to the specific schedule given.

Dosage

The typical dose is one 1mg tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.

Shelf Life

Progynova 1mg Tablet is generally stable for up to 3 to 5 years from the date of manufacture when unopened, so always check the expiry date printed on the blister strip or carton before use.

Storage Instructions

Store Progynova 1mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children.

Side Effects

  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use

Contraindications

  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy

Drug / Food Interactions

  • Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova 1mg Tablet
  • Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
  • Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
  • Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor

Quick Tips

  • Progynova 1mg Tablet is often used as a starting or step-down dose — do not change your dose without your doctor’s guidance
  • Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
  • Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
  • Give the tablet a few weeks to take effect before assuming your current dose is not working, and discuss any concerns at your next review
  • Inform your doctor of any new medical conditions or medicines started while on Progynova 1mg Tablet

Frequently Asked Questions

What is Progynova 1mg Tablet used for?

Progynova 1mg Tablet contains estradiol valerate at a lower dose and is used in hormone replacement therapy to relieve menopausal symptoms such as hot flashes, night sweats, and vaginal dryness.

Is Progynova 1mg Tablet the same as the 2mg strength?

No, Progynova 1mg Tablet contains half the estradiol valerate dose of the 2mg strength; it is often used as a starting dose for HRT or as a step-down dose once symptoms are well controlled, and your doctor will decide which strength suits you.

Do I need to take a progestogen with Progynova 1mg Tablet?

If you still have your womb, your doctor will typically prescribe a progestogen alongside Progynova 1mg Tablet to protect the womb lining, whereas women who have had a hysterectomy may only need oestrogen alone.

Who should not take Progynova 1mg Tablet?

Women with a history of breast cancer, blood clots, stroke, heart attack, severe liver disease, or undiagnosed abnormal vaginal bleeding should not take Progynova 1mg Tablet without careful doctor assessment.

What side effects can Progynova 1mg Tablet cause?

Common side effects include breast tenderness, nausea, headache, bloating, and irregular vaginal bleeding, especially in the first few months of treatment; report heavy or unusual bleeding to your doctor.

Can I purchase Progynova 1mg Tablet through DoctorOnCall in Malaysia or Singapore?

Yes, Progynova 1mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving customers in Malaysia and Singapore. As it is a prescription-only hormone medicine, an online consultation with a doctor is required so they can assess your suitability and issue a valid prescription before your order is processed.

Is Progynova 1mg Tablet supplied by DoctorOnCall genuine and safe to use for customers in Malaysia and Singapore?

Yes, all Progynova 1mg Tablet stock supplied by DoctorOnCall is sourced through licensed pharmacy supply channels and checked by a registered pharmacist before dispensing, giving customers in Malaysia and Singapore confidence in its authenticity and safety.

What payment methods can I use to pay for Progynova 1mg Tablet in Malaysia and Singapore?

DoctorOnCall accepts several convenient payment methods, including Online Banking, Credit Card, and e-Wallets (Boost, GrabPay), so customers can choose whichever option suits them best.

Does DoctorOnCall offer an installment payment plan for Progynova 1mg Tablet in Malaysia?

Instalment payment plans may be available for eligible purchases where applicable; contact DoctorOnCall’s Customer Service team for the latest information on installment options for Progynova 1mg Tablet.

Is delivery free, and how much does it cost for Progynova 1mg Tablet orders to Malaysia and Singapore?

Delivery fees depend on your location and the specific order terms; please contact DoctorOnCall’s Customer Service for the latest delivery fee information for Progynova 1mg Tablet orders.

How long will it take for my Progynova 1mg Tablet order to arrive in Malaysia or Singapore?

Orders typically take 3-5 working days to arrive within Malaysia and 5-9 working days for delivery to Singapore, though actual delivery times may vary depending on location and other factors.

What is DoctorOnCall’s shipping, return, or cancellation policy for Progynova 1mg Tablet in Malaysia and Singapore?

Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy for full details, or contact Customer Service for assistance regarding your Progynova 1mg Tablet order.

Ingredients / Active Ingredients

  • Estradiol valerate 1mg
  • Lactose monohydrate
  • Standard tablet binders and coating agents

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Progynova 1mg Tablet is often the preferred starting strength for women beginning hormone replacement therapy, or a step-down option once menopausal symptoms have stabilised on a higher dose, reflecting the general principle of using the lowest effective HRT dose. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

The typical dose is one 1mg tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.

🛑 Contraindications (Do not use if):
  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.