Progynova 1mg Tablet

Brand Bayer
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Progynova 1mg Tablet is a tablet with Estradiol valerate 1mg declared as its active content. It is supplied in a pack size of 28s.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Take Progynova 1mg Tablet exactly as prescribed by your doctor, usually one tablet daily at the same time each day, swallowed whole with water; your doctor will advise whether you are on a continuous or cyclic regimen, and if a progestogen is also prescribed, both medicines should be taken according to the specific schedule given.

Dosage

The typical dose is one 1mg tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.

Storage Instructions

Store Progynova 1mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children.

Side Effects

  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use

Contraindications

  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy

Drug / Food Interactions

  • Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova 1mg Tablet
  • Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
  • Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
  • Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor

Quick Tips

  • Progynova 1mg Tablet is often used as a starting or step-down dose — do not change your dose without your doctor’s guidance
  • Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
  • Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
  • Give the tablet a few weeks to take effect before assuming your current dose is not working, and discuss any concerns at your next review
  • Inform your doctor of any new medical conditions or medicines started while on Progynova 1mg Tablet

Ingredients / Active Ingredients

  • Estradiol valerate 1mg
  • Lactose monohydrate
  • Standard tablet binders and coating agents

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Not Advisable

Not recommended in patients with liver disease.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Progynova 1mg Tablet is often the preferred starting strength for women beginning hormone replacement therapy, or a step-down option once menopausal symptoms have stabilised on a higher dose, reflecting the general principle of using the lowest effective HRT dose. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.

Frequently Asked Questions

Product Specifications

BrandBayer
ClassificationNon-prescription
Ingredients / Active IngredientsOestradiol
Pack Size28s
Shelf LifeProgynova 1mg Tablet is generally stable for up to 3 to 5 years from the date of manufacture when unopened, so always check the expiry date printed on the blister strip or carton before use.

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Important Medical Information

💊 Recommended Dosage:

The typical dose is one 1mg tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.

🛑 Contraindications (Do not use if):
  • Known, past, or suspected breast cancer or other oestrogen-dependent cancer
  • Undiagnosed abnormal vaginal bleeding
  • Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
  • Active or recent arterial disease such as heart attack or stroke
  • Severe liver disease or liver tumours
  • Known or suspected pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Breast tenderness or swelling
  • Headache or migraine
  • Bloating
  • Mood changes
  • Spotting or breakthrough bleeding
  • Increased risk of blood clots with long-term use
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.