Sandimmun Neoral 100mg Capsule
Rx- Fast Delivery
- Muslim-Friendly
- FDA Approved
- Secure Payment
Prescription Required
Overview
Sandimmun Neoral 100mg Capsule contains ciclosporin 100mg in a microemulsion capsule formulation, a potent immunosuppressant used to prevent organ rejection after kidney, liver or heart transplantation, and to treat certain severe autoimmune conditions such as severe rheumatoid arthritis, severe psoriasis, and nephrotic syndrome, when prescribed by a specialist. This is a high-risk medicine that requires ongoing specialist supervision and regular blood monitoring throughout treatment.
Ciclosporin works by inhibiting calcineurin, an enzyme needed to activate T-lymphocytes (a type of white blood cell central to the immune response). By suppressing T-cell activation, it reduces the immune system’s ability to attack a transplanted organ or drive autoimmune inflammation.
How it Works
Ciclosporin binds to a protein called cyclophilin inside T-lymphocytes, and this complex inhibits calcineurin, an enzyme required to switch on genes that drive T-cell activation and the production of interleukin-2. This selectively dampens the part of the immune system responsible for rejecting transplanted tissue or attacking the body’s own tissues in autoimmune disease.
Directions for Use
Take Sandimmun Neoral 100mg Capsule at the same time(s) each day, and consistently either always with food or always without food, exactly as your doctor instructs, as switching can change how much medicine your body absorbs. Do not switch between different ciclosporin brands or formulations without your specialist’s explicit direction, as they are not automatically interchangeable. Attend every scheduled blood test appointment so your doctor can monitor your ciclosporin level, kidney function and blood pressure.
Dosage
The dose of Sandimmun Neoral 100mg Capsule is highly individualised by your transplant or specialist physician, based on your body weight, the organ transplanted or condition being treated, and regular measurement of your ciclosporin blood (trough) levels. There is no standard fixed dose – your doctor will adjust your dose based on blood test results, kidney function, and clinical response, so never change your dose without specialist guidance.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- High blood pressure
- Increased hair growth
- Kidney problems
- Headache
- Nausea
- Swollen gums
- Tremors
- Fatigue
Contraindications
- Known hypersensitivity to ciclosporin or any ingredient in this product
- Uncontrolled high blood pressure
- Uncontrolled active infections
- Active malignancy (other than certain skin cancers being treated)
- Concomitant use with St John’s Wort (reduces ciclosporin levels significantly)
Drug / Food Interactions
- Grapefruit juice significantly increases ciclosporin blood levels and must be avoided
- Azole antifungals and certain macrolide antibiotics (e.g. ketoconazole, erythromycin) increase ciclosporin levels and toxicity risk
- Rifampicin and St John’s Wort reduce ciclosporin levels, risking transplant rejection or disease flare
- NSAIDs, aminoglycoside antibiotics, and potassium-sparing diuretics increase the risk of kidney impairment or high blood potassium when combined with ciclosporin
Quick Tips
- Never miss a scheduled blood test – ciclosporin blood levels must be monitored closely to keep the dose safe and effective
- Never switch ciclosporin brands or formulations without your specialist’s approval
- Avoid grapefruit and grapefruit juice completely while on this medicine
- Report any signs of infection, fever, or unusual bleeding to your care team immediately
- Avoid live vaccines while taking this medicine unless specifically approved by your specialist
- Attend regular blood pressure and kidney function checks as scheduled
Frequently Asked Questions
What is Sandimmun Neoral 100mg Capsule used for?
Sandimmun Neoral 100mg Capsule is a specialist-prescribed immunosuppressant used to prevent rejection after organ transplantation and to treat certain severe autoimmune conditions. Your specialist will confirm the specific reason it has been prescribed for you.
Why do I need frequent blood tests while taking this medicine?
Ciclosporin has a narrow safety margin – too little may risk organ rejection or disease flare, while too much increases the risk of kidney damage and other side effects. Regular blood tests let your specialist keep your dose in the safe, effective range.
Can I switch to a different brand of ciclosporin if my usual one is unavailable?
No, not without your specialist’s explicit approval. Different ciclosporin formulations are not automatically interchangeable, as absorption can differ between brands, potentially affecting your blood levels and risking rejection or toxicity.
Why must I avoid grapefruit while on this medicine?
Grapefruit and grapefruit juice interfere with the enzyme that breaks down ciclosporin in the body, causing blood levels to rise unpredictably and increasing the risk of side effects such as kidney impairment.
Is this medicine safe to take long-term?
Ciclosporin is used long-term for transplant patients under close specialist supervision, with regular monitoring of kidney function, blood pressure, and blood levels to manage risks such as kidney impairment, high blood pressure, and increased infection susceptibility.
What should I do if I miss a dose of Sandimmun Neoral 100mg Capsule?
Contact your transplant team or specialist for specific advice, as missed doses of ciclosporin can be more consequential than with many other medicines – do not simply double your next dose without guidance.
Can I buy Sandimmun Neoral 100mg Capsule from DoctorOnCall?
Yes, Sandimmun Neoral 100mg Capsule is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Sandimmun Neoral 100mg Capsule according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Sandimmun Neoral 100mg Capsule?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Sandimmun Neoral 100mg Capsule cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Sandimmun Neoral 100mg Capsule?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Sandimmun Neoral 100mg Capsule?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Ciclosporin 100mg (microemulsion formulation)
Safety Advice
Pregnancy
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
