Acetan HCT 100/25mg Tablet

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Complete your checkout to get your prescription approved. A doctor will contact you within 30 minute(s) after payment.

Overview

Acetan HCT 100/25mg Tablet is a combination tablet containing losartan 100mg, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide 25mg, a thiazide diuretic (‘water pill’). It is used to treat high blood pressure that is not adequately controlled by either medicine alone.

Losartan relaxes blood vessels by blocking the hormone angiotensin II, while hydrochlorothiazide helps the kidneys remove extra salt and water from the body. Together, these two mechanisms provide a stronger blood-pressure-lowering effect than either medicine used on its own.

How it Works

Losartan selectively blocks the AT1 receptor, preventing angiotensin II from narrowing blood vessels and triggering aldosterone-driven salt retention. Hydrochlorothiazide acts on the distal renal tubule to reduce sodium and water reabsorption, increasing urine output. The combined vasodilation and reduced fluid volume produce an additive drop in blood pressure.

Directions for Use

Take Acetan HCT 100/25mg Tablet in the morning where possible, as the diuretic component can increase urination and may disturb sleep if taken late in the day. It can be taken with or without food, at the same time each day.

Dosage

Acetan HCT 100/25mg Tablet is usually taken once daily, with your doctor selecting the appropriate strength based on your blood pressure response and how well you tolerate the medicine. Do not change between strengths without your doctor’s advice.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or light-headedness
  • Increased urination
  • Headache
  • Nausea or vomiting
  • Muscle cramps or weakness
  • Sensitivity to sunlight

Contraindications

  • Known hypersensitivity to losartan, hydrochlorothiazide, or sulfonamide-derived medicines
  • Anuria (inability to produce urine) or severe kidney impairment
  • Pregnancy (can cause harm to the developing baby)
  • Severe liver impairment
  • Refractory low blood potassium or low blood sodium

Drug / Food Interactions

  • Potassium supplements or potassium-sparing diuretics may raise blood potassium when combined with losartan, while hydrochlorothiazide can lower it – your doctor will monitor your electrolytes
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
  • Lithium levels may increase when combined with either component
  • Other blood pressure medicines may increase the risk of low blood pressure

Quick Tips

  • Attend scheduled blood tests to monitor your kidney function and electrolyte (sodium/potassium) levels
  • Use sun protection, as this medicine can make your skin more sensitive to sunlight
  • Rise slowly from sitting or lying down to reduce dizziness
  • Monitor your blood pressure regularly as advised by your doctor

Frequently Asked Questions

What is Acetan HCT 100/25mg Tablet used for?

Acetan HCT 100/25mg Tablet is used to treat high blood pressure that has not been fully controlled by a single blood pressure medicine, combining an ARB with a diuretic for a stronger effect.

What is the difference between the two strengths of this product?

The two strengths contain different amounts of losartan and hydrochlorothiazide. Your doctor selects the strength that best controls your blood pressure while minimising side effects – do not switch strengths on your own.

Can I take this medicine if I am pregnant?

No. This combination should not be used during pregnancy as it can seriously harm the developing baby. Speak to your doctor immediately if you are pregnant or planning pregnancy.

Why does this medicine make me more sensitive to the sun?

Hydrochlorothiazide can cause photosensitivity, making sunburn more likely. Use sunscreen and protective clothing, and avoid excessive sun exposure while taking this medicine.

What should I do if I miss a dose of Acetan HCT 100/25mg Tablet?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue as normal. Do not double the dose.

Can I buy Acetan HCT 100/25mg Tablet from DoctorOnCall?

Yes, Acetan HCT 100/25mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Acetan HCT 100/25mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Acetan HCT 100/25mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Acetan HCT 100/25mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Acetan HCT 100/25mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Acetan HCT 100/25mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Losartan potassium 100mg
  • Hydrochlorothiazide 25mg

Safety Advice

Pregnancy

No Data

There is no adequate data on use during pregnancy. Consult a doctor before use.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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