Alcon Simbrinza 10mg/ml Eye Drop

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Brand Alcon
Manufacturer Alcon
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Alcon Simbrinza 10mg/ml Eye Drop contains Brinzolamide 10mg/ml and Brimonidine tartrate 2mg/ml and is available as eye drops. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Alcon Simbrinza 10mg/ml Eye Drop are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Shake Alcon Simbrinza 10mg/ml Eye Drop well before use. Tilt your head back, pull down the lower eyelid to form a pocket, and instil one drop without letting the tip touch your eye. Press gently on the inner corner of the eye for about a minute after instillation, and wait at least 5 minutes before using any other eye drop.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

Brimonidine

  • Eye redness or irritation
  • Blurred vision
  • Dry eyes
  • Fatigue or drowsiness
  • Headache
  • Mild stinging or burning sensation in the eyes
  • Sensitivity to light

Brinzolamide

  • Blurred vision
  • Eye discomfort or stinging
  • Bitter taste in the mouth
  • Dry eyes
  • Headache
  • Sensitivity to light
  • Redness of the eye
  • Feeling like something is in your eye

Contraindications

  • Known hypersensitivity to brinzolamide, brimonidine, or sulfonamide-derived medicines
  • Severe kidney impairment
  • Infants and young children (brimonidine component carries a risk of central nervous system depression)
  • Concurrent use with monoamine oxidase inhibitors (MAOIs)

Drug / Food Interactions

  • High-dose salicylates (aspirin) may interact with the carbonic anhydrase inhibitor component
  • Other sulfonamide-derived medicines may have additive effects or increase the risk of sensitivity reactions
  • CNS depressants (alcohol, sedatives) may increase drowsiness from the brimonidine component
  • MAOIs may affect the metabolism of brimonidine and should be discussed with your doctor

Quick Tips

  • Shake the bottle well before every use, as this is a suspension
  • Wait at least 5 minutes before using a different eye drop
  • Vision may be temporarily blurred right after use – avoid driving or operating machinery until it clears
  • Press on the inner corner of your eye after each drop to reduce absorption into the bloodstream

Ingredients / Active Ingredients

  • Brinzolamide 10mg/ml
  • Brimonidine tartrate 2mg/ml

Safety Advice

Brimonidine

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Limited Data

Limited data available in liver disease patients.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Brinzolamide

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Not Advisable

Not generally recommended in patients with kidney disease.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

BrandAlcon
ManufacturerAlcon
ClassificationPrescription medicine
Ingredients / Active IngredientsBrimonidine, Brinzolamide
Volume5ml
DosageThe usual dose of Alcon Simbrinza 10mg/ml Eye Drop is one drop in the affected eye(s) three times daily, as instructed by your eye doctor, evenly spaced through the day for consistent pressure control.
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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