Installment Available Combigan Eye Drop
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- Muslim-Friendly
- FDA Approved
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- 0% InterestNo interest on eligible instalments
- Flexible paymentsSpread your payment across monthly instalments
- No hidden feesClear and transparent pricing
Prescription Required
Overview
Combigan Eye Drop is a prescription-only medicine (POM) that contains Brimonidine tartrate 0.2% and Timolol 0.5% (as timolol maleate). It is supplied as eye drops and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.
Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.
On DoctorOnCall, Combigan Eye Drop is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.
Directions for Use
Wash your hands, tilt your head back, gently pull down your lower eyelid to form a small pocket, and instil one drop of Combigan Eye Drop without letting the dropper tip touch your eye or eyelid. Close your eyes gently and press a finger against the inner corner of the eye for about 2 minutes to reduce the amount absorbed into your bloodstream, and wait at least 5 minutes before using any other eye drop.
Dosage
The usual dose of Combigan Eye Drop is one drop in the affected eye or eyes, twice daily, about 12 hours apart, though your ophthalmologist will confirm the exact schedule for your condition and monitor your eye pressure regularly to check the response to treatment.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 25°C, away from direct sunlight and out of reach of children. Discard the bottle 4 weeks after first opening, even if some solution remains, as the drops may no longer be sterile.
Side Effects
- Eye redness or irritation
- Blurred vision
- Dry eyes
- Fatigue or drowsiness
- Headache
- Mild stinging or burning sensation in the eyes
- Sensitivity to light
Contraindications
- Known hypersensitivity to brimonidine, timolol, or any ingredient in this product
- Reactive airway disease, including asthma, or severe chronic obstructive pulmonary disease
- Sinus bradycardia, second- or third-degree heart block, or decompensated heart failure
- Use in infants and neonates
- Concomitant use with monoamine oxidase (MAO) inhibitors
Drug / Food Interactions
- Oral beta-blockers or calcium channel blockers may add to timolol’s effect on heart rate and blood pressure
- CNS depressants or alcohol may increase drowsiness caused by brimonidine
- Other topical or systemic blood-pressure-lowering medicines may increase the risk of low blood pressure
- MAO inhibitors may increase brimonidine’s cardiovascular effects and should generally be avoided together
Quick Tips
- Press gently on the inner corner of your eye after each drop to reduce how much medicine enters your bloodstream
- Wait at least 5 minutes before instilling a different eye drop if you use more than one
- Tell every doctor you see, including your GP, that you use this eye drop, as it can affect heart rate and blood pressure
- Do not stop this medicine without consulting your ophthalmologist, even if your eyes feel comfortable, as glaucoma often has no symptoms
Frequently Asked Questions
Is Combigan Eye Drop a prescription medicine?
Yes. Combigan Eye Drop is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Combigan Eye Drop contain?
Combigan Eye Drop is supplied as eye drops and contains Brimonidine tartrate 0.2% and Timolol 0.5% (as timolol maleate). The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Combigan Eye Drop is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Combigan Eye Drop?
Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Combigan Eye Drop?
Store below 25°C, away from direct sunlight and out of reach of children. Discard the bottle 4 weeks after first opening, even if some solution remains, as the drops may no longer be sterile. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Combigan Eye Drop on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Combigan Eye Drop?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Combigan Eye Drop be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Combigan Eye Drop registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Brimonidine tartrate 0.2%
- Timolol 0.5% (as timolol maleate)
Safety Advice
Pregnancy
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Limited data available in liver disease patients.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
