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Overview
Apo Terbinafine 250mg Tablet contains terbinafine 250mg, an antifungal medicine used to treat fungal infections of the skin, nails (onychomycosis), and scalp caused by susceptible dermatophyte fungi, taken orally for infections that do not respond adequately to topical treatment.
Terbinafine works by blocking an enzyme fungi need to build their cell membrane, causing a build-up of a toxic substance inside the fungal cell and a deficiency of a substance it needs to survive, which kills the fungus (a fungicidal, rather than just fungus-suppressing, action).
How it Works
Terbinafine inhibits squalene epoxidase, an enzyme in the fungal cell membrane synthesis pathway. This causes squalene to accumulate to toxic levels within the fungal cell while depleting ergosterol, an essential component of the fungal cell membrane, ultimately killing the fungus.
Directions for Use
Take Apo Terbinafine 250mg Tablet once daily, at about the same time each day, with or without food. Swallow the tablet whole with water. Complete the full course as prescribed, even if your symptoms improve early, as stopping too soon can allow the infection to return.
Dosage
The usual dose of Apo Terbinafine 250mg Tablet is 250mg once daily, with treatment duration depending on the site and severity of infection – commonly 2-6 weeks for skin infections and up to 6-12 weeks or longer for nail infections. Your doctor will determine the appropriate course length for your infection.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Nausea or upset stomach
- Diarrhoea
- Skin rash or itching
- Taste changes or loss of taste
- Abnormal liver function tests
- Fatigue
- Muscle or joint pain
Contraindications
- Known hypersensitivity to terbinafine or any ingredient in this product
- Active or chronic liver disease
- Severe kidney impairment without dose adjustment
Drug / Food Interactions
- Rifampicin can reduce terbinafine blood levels, potentially reducing its effectiveness
- Cimetidine can increase terbinafine blood levels
- Certain antidepressants and other medicines metabolised by the same liver enzyme (CYP2D6) may have altered levels when combined
- Alcohol may increase the risk of liver-related side effects and should be limited during treatment
Quick Tips
- Complete the full prescribed course, even for nail infections that take months to fully clear as the nail regrows
- Attend liver function blood tests if your doctor recommends them for a prolonged course
- Report any unusual tiredness, loss of appetite, nausea, or yellowing of the skin/eyes promptly
- Maintain good foot/nail hygiene and keep the affected area clean and dry alongside treatment
Frequently Asked Questions
What is Apo Terbinafine 250mg Tablet used for?
Apo Terbinafine 250mg Tablet is used to treat fungal infections of the skin, scalp, and nails, particularly nail infections (onychomycosis) that need oral treatment to reach the infection under the nail.
Why does it take so long to see results, especially for nail infections?
Nails grow slowly, so even after the fungus is cleared, it takes several months for a healthy nail to fully grow out and replace the infected part. Full nail clearance can take up to a year for toenails.
Do I need blood tests while taking this medicine?
Your doctor may recommend liver function tests before and during a prolonged course, since terbinafine is processed by the liver and can, rarely, affect liver function.
Can I drink alcohol while taking this medicine?
It is best to limit alcohol during treatment, as both alcohol and terbinafine are processed by the liver, and combining them may increase the risk of liver-related side effects.
What should I do if I miss a dose of Apo Terbinafine 250mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Apo Terbinafine 250mg Tablet from DoctorOnCall?
Yes, Apo Terbinafine 250mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Apo Terbinafine 250mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Apo Terbinafine 250mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Apo Terbinafine 250mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Apo Terbinafine 250mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Apo Terbinafine 250mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Terbinafine 250mg (as terbinafine hydrochloride)
Related Health Conditions
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use only if prescribed, with possible monitoring of kidney function.
Liver
Not recommended in patients with liver disease.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
Reviewed by:
Doctor of Medicine (MD), University of Mansoura - Manchester


