Dermovate 0.05% Cream

Brand GSK
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Dermovate 0.05% Cream contains Clobetasol Propionate 0.05% and is presented as a cream. It is supplied in pack sizes of 100g and 15g.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

Dermovate 0.05% Cream must be used exactly as prescribed. A thin layer is applied to the affected area, usually once or twice daily, and gently rubbed in until absorbed, taking care to avoid the face, groin, underarms, and broken skin unless the doctor has specifically instructed otherwise. It should not be used under occlusive dressings unless explicitly advised.

Dosage

Treatment courses with Dermovate 0.05% Cream are typically restricted to a maximum of a few weeks at a time, with a weekly quantity limit set by the prescribing doctor to reduce the risk of systemic absorption. The doctor will reassess the skin condition before authorising any further course of treatment.

Storage Instructions

Store Dermovate 0.05% Cream below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the tube tightly closed after each use and well out of reach of children.

Side Effects

  • Burning, stinging or irritation at the application site
  • Dry or cracked skin
  • Skin thinning (with prolonged use)
  • Changes in skin color
  • Stretch marks
  • Acne or increased hair growth on treated areas

Contraindications

  • Known hypersensitivity to Clobetasol Propionate or any other ingredient in the cream
  • Untreated bacterial, viral, or fungal skin infections at the application site
  • Rosacea, perioral dermatitis, or acne vulgaris
  • Use on the face, groin, or underarms without explicit medical instruction
  • Use in children without close specialist supervision, as they are more susceptible to systemic effects

Drug / Food Interactions

  • Concurrent use with other potent topical corticosteroids increases the risk of skin thinning and systemic absorption
  • Use with occlusive dressings significantly increases systemic absorption and must only be done if specifically directed by the doctor
  • Applying other topical medicated products to the same area should be discussed with the prescribing doctor

Quick Tips

  • Use strictly for the duration and quantity limits set by your doctor, never longer
  • Apply only a thin layer; more product does not improve results and increases risk
  • The cream base absorbs quickly and suits weeping or moist lesions better than a heavier ointment
  • Attend all follow-up appointments so your doctor can monitor your skin and overall response
  • Report any signs of infection, unusual skin changes, or systemic symptoms promptly

Ingredients / Active Ingredients

  • Clobetasol Propionate 0.05%
  • Cream base with emollient and stabilising excipients

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Generally Safe

This medicine is generally safe and should not impair your driving ability.

Relevant Information

Dermovate 0.05% Cream is reserved for severe, treatment-resistant inflammatory skin conditions and offers a lighter, faster-absorbing alternative to the ointment formulation, making it a preferred choice for acute or moist lesions, larger body surface areas, or in warmer, humid climates where a greasy ointment may feel uncomfortable. Its use still requires careful medical oversight to balance effective control of the condition against the risk of significant skin and systemic side effects, often followed by a step-down to a less potent steroid once the condition improves.

Frequently Asked Questions

Product Specifications

BrandGSK
ClassificationNon-prescription
Ingredients / Active IngredientsClobetasol
Weight100g, 15g
Shelf LifeDermovate 0.05% Cream is generally valid for up to 24 to 36 months from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the tube or carton before use.

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Important Medical Information

💊 Recommended Dosage:

Treatment courses with Dermovate 0.05% Cream are typically restricted to a maximum of a few weeks at a time, with a weekly quantity limit set by the prescribing doctor to reduce the risk of systemic absorption. The doctor will reassess the skin condition before authorising any further course of treatment.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to Clobetasol Propionate or any other ingredient in the cream
  • Untreated bacterial, viral, or fungal skin infections at the application site
  • Rosacea, perioral dermatitis, or acne vulgaris
  • Use on the face, groin, or underarms without explicit medical instruction
  • Use in children without close specialist supervision, as they are more susceptible to systemic effects
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Burning, stinging or irritation at the application site
  • Dry or cracked skin
  • Skin thinning (with prolonged use)
  • Changes in skin color
  • Stretch marks
  • Acne or increased hair growth on treated areas
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.