Exforge HCT 10/160/12.5mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Exforge HCT 10/160/12.5mg Tablet contains Amlodipine 10mg (as amlodipine besylate), Valsartan 160mg and Hydrochlorothiazide 12.5mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Exforge HCT 10/160/12.5mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Exforge HCT exactly as prescribed by your doctor, generally once daily at the same time each day, with or without food, and swallow the tablet whole with water. Do not adjust the dose or stop the medicine on your own, as abrupt discontinuation can cause blood pressure to rebound; any dose changes should only be made after a follow-up review with your prescribing doctor.

Dosage

The dosage is individualised by the prescribing doctor based on prior response to dual therapy (amlodipine/valsartan or valsartan/hydrochlorothiazide) and is not intended as a first-line starting treatment. Regular blood pressure checks and periodic blood tests for kidney function and electrolytes (particularly potassium and sodium) are recommended while on this combination, and only a doctor should adjust the strength if blood pressure remains high or if side effects occur.

Shelf Life

Exforge HCT tablets are typically stable for up to 36 months from the date of manufacture when stored unopened in original packaging; always check the expiry date printed on the blister or carton before use.

Storage Instructions

Store below 30°C in a dry place away from direct sunlight and moisture, and keep the tablets in their original blister packaging until just before use to protect them from humidity. Keep out of reach of children.

Side Effects

  • Headache
  • Dizziness or lightheadedness
  • Swelling of the ankles or feet
  • Fatigue
  • Flushing (warmth or redness in face/skin)
  • Nausea

Contraindications

  • Known hypersensitivity to amlodipine, valsartan, hydrochlorothiazide, other sulfonamide-derived drugs, or any component of the tablet
  • Pregnancy or planning pregnancy — angiotensin receptor blockers can harm the unborn baby, especially in the second and third trimesters
  • Severe kidney impairment or anuria (inability to pass urine)
  • Severe liver impairment or biliary obstruction
  • Uncontrolled low potassium, low sodium, or high calcium levels that have not been corrected
  • Severe, uncorrected low blood pressure

Drug / Food Interactions

  • Other blood pressure medicines or nitrates may increase the risk of excessive blood pressure drops
  • NSAIDs (such as ibuprofen or diclofenac) taken regularly may reduce the blood-pressure-lowering effect and increase the risk of kidney problems
  • Potassium supplements, potassium-sparing diuretics, or salt substitutes containing potassium may raise blood potassium to unsafe levels
  • Lithium levels in the blood may rise when taken with this combination, requiring closer monitoring
  • Grapefruit juice may increase amlodipine levels in some individuals and is best avoided or limited
  • Alcohol can intensify dizziness and low blood pressure effects

Quick Tips

  • Attend all scheduled follow-up appointments so your doctor can monitor blood pressure, kidney function, and electrolyte levels
  • Rise slowly from sitting or lying positions to reduce dizziness, particularly when starting treatment
  • Do not stop this medicine suddenly without medical advice, even if you feel well
  • Tell your doctor about all other medicines and supplements you are taking, including over-the-counter painkillers
  • Report unusual muscle weakness, cramping, or persistent dizziness to your doctor promptly, as these may signal an electrolyte imbalance

Frequently Asked Questions

Is Exforge HCT 10/160/12.5mg Tablet a prescription medicine?

Yes. Exforge HCT 10/160/12.5mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.

What does Exforge HCT 10/160/12.5mg Tablet contain?

Exforge HCT 10/160/12.5mg Tablet is supplied as a tablet and contains Amlodipine 10mg (as amlodipine besylate), Valsartan 160mg and Hydrochlorothiazide 12.5mg. The full composition is listed in the Composition section on this page and on the product packaging.

Why is there no information here about what Exforge HCT 10/160/12.5mg Tablet is for?

Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.

How should I take Exforge HCT 10/160/12.5mg Tablet?

Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.

What should I do if I miss a dose?

Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.

How should I store Exforge HCT 10/160/12.5mg Tablet?

Store below 30°C in a dry place away from direct sunlight and moisture, and keep the tablets in their original blister packaging until just before use to protect them from humidity. Keep out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects?

Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

Can I stop taking Exforge HCT 10/160/12.5mg Tablet on my own?

No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.

How do I get a prescription for Exforge HCT 10/160/12.5mg Tablet?

Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.

Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.

Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.

FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Exforge HCT 10/160/12.5mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.

Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Exforge HCT 10/160/12.5mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.

An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.

For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Ingredients / Active Ingredients

  • Amlodipine besylate (equivalent to amlodipine 10mg) — calcium channel blocker
  • Valsartan 160mg — angiotensin II receptor blocker
  • Hydrochlorothiazide 12.5mg — thiazide diuretic
  • Standard tablet excipients
  • Amlodipine 10mg (as amlodipine besylate)
  • Valsartan 160mg
  • Hydrochlorothiazide 12.5mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Exforge HCT is reserved for patients whose hypertension has proven difficult to control on two-drug regimens, and its triple mechanism means it is not typically used as an initial treatment for newly diagnosed high blood pressure. Because it combines a diuretic with two other blood-pressure-lowering agents, ongoing monitoring of kidney function and electrolytes is an important part of safe long-term use, and any dose or regimen changes should always go through the prescribing doctor.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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