Humalog Mix 50 100IU/ml Kwikpen

Manufacturer Humalog
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Humalog Mix 50 100IU/ml Kwikpen contains Insulin lispro 100 IU/ml (50% rapid-acting solution / 50% protamine suspension) and is presented as a healthcare product. It is supplied in a pack size of 5s x 3ml.

It is classified as a non-prescription medicine, so no prescription is needed to order it. Under Malaysian rules for medicine information, this page carries product, safety and handling information only.

You can consult a doctor or pharmacist online on DoctorOnCall about this product before or after you order. Every order is checked by a registered pharmacist before it is delivered. Always read the label and the leaflet supplied with the pack.

Directions for Use

This medicine must be used exactly as prescribed by your doctor, who will explain the injection technique, injection sites (such as the abdomen, thigh, or upper arm), and how to rotate sites to reduce the risk of lipodystrophy. The Kwikpen must be gently rolled and tipped (not shaken) to remix the suspension evenly before each injection, and a new needle should be used for every dose; do not adjust the dose or stop using this medicine without first consulting your prescribing doctor.

Dosage

Dosage is individualised and must be determined and adjusted by a doctor based on blood glucose monitoring results, meal patterns, activity level, and overall diabetes control; there is no standard over-the-counter dose. Doses are typically given shortly before or immediately after a meal, exactly as instructed by the prescribing doctor, and should never be changed without medical advice.

Shelf Life

An unopened Humalog Mix 50 Kwikpen should be stored refrigerated and is generally stable until the expiry date printed on the pen and carton when kept under these conditions. Once a pen is in use (opened), it is typically only usable for up to 28 days as advised by the prescribing doctor or pharmacist, after which any remaining insulin in that pen must be discarded even if it has not run out.

Storage Instructions

Store unopened Kwikpens in a refrigerator at 2°C to 8°C; do not freeze, and do not use if the insulin has been frozen. Once in use, the pen currently being used may generally be kept at room temperature below 30°C, away from direct heat and sunlight, and must be discarded after the in-use period advised by your doctor or pharmacist. Always keep out of the sight and reach of children, and never share your insulin pen with another person.

Side Effects

  • Low blood sugar (hypoglycaemia)
  • Weight gain
  • Injection site redness or swelling
  • Headache
  • Dizziness
  • Sweating or shakiness

Contraindications

  • Known hypersensitivity to insulin lispro or any other ingredient in the pen
  • Episodes of hypoglycaemia that have not been discussed and managed with your doctor
  • Use without proper medical supervision, blood glucose monitoring, and dose titration by a doctor

Drug / Food Interactions

  • Oral antidiabetic medicines, which may need dose adjustment when combined with insulin
  • Corticosteroids, which can raise blood glucose and affect insulin requirements
  • Beta-blockers, which may mask the warning symptoms of hypoglycaemia
  • Alcohol, which can increase the risk of hypoglycaemia
  • Missed or delayed meals, which significantly increase the risk of hypoglycaemia after an insulin dose

Quick Tips

  • Never change your insulin dose or schedule without your doctor’s advice
  • Always check your blood glucose as instructed and know the signs of hypoglycaemia
  • Rotate injection sites regularly to prevent lipodystrophy
  • Roll and gently tip the pen to remix the suspension before each use; do not shake vigorously
  • Carry a fast-acting source of sugar with you in case of hypoglycaemia
  • Attend regular follow-up appointments with your doctor to monitor overall diabetes control

Ingredients / Active Ingredients

  • Insulin lispro 100 IU/ml (50% rapid-acting solution / 50% protamine suspension)
  • Protamine sulfate
  • Metacresol
  • Phenol
  • Glycerol
  • Zinc oxide
  • Water for injection

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Humalog Mix 50 Kwikpen is a prescription-only injectable insulin and must always be used under the ongoing supervision of a doctor, with regular blood glucose monitoring and periodic review of the treatment plan. Correct storage before first use (refrigeration between 2°C and 8°C, never frozen) and correct injection technique are essential to ensure the medicine works as expected; patients should be trained by a healthcare professional on how to use the Kwikpen device, rotate injection sites, and recognise and manage hypoglycaemia before starting treatment. Through DoctorOnCall, an online consultation with a doctor is required before this medicine can be prescribed and dispensed.

Frequently Asked Questions

Product Specifications

ManufacturerHumalog
ClassificationNon-prescription
Ingredients / Active IngredientsInsulin
Pack Contents5s x 3ml

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Important Medical Information

💊 Recommended Dosage:

Dosage is individualised and must be determined and adjusted by a doctor based on blood glucose monitoring results, meal patterns, activity level, and overall diabetes control; there is no standard over-the-counter dose. Doses are typically given shortly before or immediately after a meal, exactly as instructed by the prescribing doctor, and should never be changed without medical advice.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to insulin lispro or any other ingredient in the pen
  • Episodes of hypoglycaemia that have not been discussed and managed with your doctor
  • Use without proper medical supervision, blood glucose monitoring, and dose titration by a doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Low blood sugar (hypoglycaemia)
  • Weight gain
  • Injection site redness or swelling
  • Headache
  • Dizziness
  • Sweating or shakiness
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.