Irbemac H 300/12.5 Tablet

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Manufacturer Synerrv
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

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Overview

Irbemac H 300/12.5 Tablet is a prescription-only medicine (POM) presented as a tablet, with Irbesartan 300mg and Hydrochlorothiazide 12.5mg as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take Irbemac H 300/12.5 Tablet at about the same time every day, with or without food. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.

Dosage

Irbemac H 300/12.5 Tablet is usually taken once daily, with your doctor determining the correct strength for you based on your blood pressure response and any dose you may already be taking of either component separately. Blood pressure control is usually assessed after a few weeks of treatment, and your doctor may adjust your regimen based on your response.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Dizziness or lightheadedness, especially when standing up
  • Fatigue or tiredness
  • Nausea
  • Headache
  • High potassium levels (may show as muscle weakness or irregular heartbeat)
  • Back pain

Contraindications

  • Known hypersensitivity to irbesartan, hydrochlorothiazide, other sulfonamide-derived medicines, or any ingredient in this product
  • Pregnancy (can cause harm to the developing baby, especially in the second and third trimester)
  • Anuria (inability to produce urine) or severe kidney impairment
  • Severe liver impairment
  • Concomitant use with aliskiren in patients with diabetes or kidney impairment

Drug / Food Interactions

  • Potassium supplements or potassium-sparing diuretics may increase the risk of abnormal blood potassium, as the two components can affect potassium differently
  • NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
  • Lithium levels may increase when combined with this medicine, raising the risk of lithium toxicity
  • Other blood pressure medicines or alcohol may increase the risk of low blood pressure or dizziness

Quick Tips

  • Take at the same time each day to build a consistent routine
  • Monitor your blood pressure regularly as advised by your doctor
  • Attend scheduled blood tests to check your kidney function and electrolyte (sodium/potassium) levels
  • Rise slowly from sitting or lying down to reduce dizziness
  • Do not stop this medicine abruptly without medical advice
  • Inform your doctor before starting any new supplement, especially potassium

Ingredients / Active Ingredients

  • Irbesartan 300mg
  • Hydrochlorothiazide 12.5mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Frequently Asked Questions

Product Specifications

ManufacturerSynerrv
ClassificationPrescription medicine
Ingredients / Active IngredientsIrbesartan
Pack Size28s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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