Irbemac H 300/12.5 Tablet
Rx- Fast Delivery
- Muslim-Friendly
- FDA Approved
- Secure Payment
Prescription Required
Overview
Irbemac H 300/12.5 Tablet contains irbesartan 300mg and hydrochlorothiazide 12.5mg, a combination of an angiotensin II receptor blocker (ARB) and a thiazide diuretic used to treat high blood pressure (hypertension) that is not adequately controlled by either medicine alone.
Irbesartan lowers blood pressure by blocking the action of angiotensin II, a hormone that narrows blood vessels, allowing them to relax and widen. Hydrochlorothiazide works differently, helping the kidneys remove excess salt and water from the body, which reduces the volume of fluid in the blood vessels. Together, these two mechanisms give a stronger blood-pressure-lowering effect than either medicine used alone.
How it Works
Irbesartan selectively blocks the AT1 receptor, preventing angiotensin II from narrowing blood vessels and promoting sodium retention. Hydrochlorothiazide acts on the kidneys, reducing reabsorption of sodium and water in the distal tubule so that more is excreted in urine. The combined effect is a reduction in blood vessel resistance and circulating fluid volume, both of which lower blood pressure.
Directions for Use
Take Irbemac H 300/12.5 Tablet at about the same time every day, with or without food. Swallow the tablet whole with a glass of water. Do not stop taking this medicine suddenly without consulting your doctor, even if you feel well, as blood pressure control needs to be continuous.
Dosage
Irbemac H 300/12.5 Tablet is usually taken once daily, with your doctor determining the correct strength for you based on your blood pressure response and any dose you may already be taking of either component separately. Blood pressure control is usually assessed after a few weeks of treatment, and your doctor may adjust your regimen based on your response.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or lightheadedness, especially when standing up
- Fatigue or tiredness
- Nausea
- Headache
- High potassium levels (may show as muscle weakness or irregular heartbeat)
- Back pain
Contraindications
- Known hypersensitivity to irbesartan, hydrochlorothiazide, other sulfonamide-derived medicines, or any ingredient in this product
- Pregnancy (can cause harm to the developing baby, especially in the second and third trimester)
- Anuria (inability to produce urine) or severe kidney impairment
- Severe liver impairment
- Concomitant use with aliskiren in patients with diabetes or kidney impairment
Drug / Food Interactions
- Potassium supplements or potassium-sparing diuretics may increase the risk of abnormal blood potassium, as the two components can affect potassium differently
- NSAIDs (e.g. ibuprofen) may reduce the blood-pressure-lowering effect and affect kidney function
- Lithium levels may increase when combined with this medicine, raising the risk of lithium toxicity
- Other blood pressure medicines or alcohol may increase the risk of low blood pressure or dizziness
Quick Tips
- Take at the same time each day to build a consistent routine
- Monitor your blood pressure regularly as advised by your doctor
- Attend scheduled blood tests to check your kidney function and electrolyte (sodium/potassium) levels
- Rise slowly from sitting or lying down to reduce dizziness
- Do not stop this medicine abruptly without medical advice
- Inform your doctor before starting any new supplement, especially potassium
Frequently Asked Questions
What is Irbemac H 300/12.5 Tablet used for?
Irbemac H 300/12.5 Tablet is a combination medicine used to treat high blood pressure that is not fully controlled by a single blood pressure medicine alone.
Why does this tablet contain two different medicines?
Irbesartan and hydrochlorothiazide lower blood pressure through different mechanisms, so combining them in one tablet can achieve better blood pressure control than either medicine used on its own.
Can I stop taking this medicine if my blood pressure normalises?
No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause your blood pressure to rise again.
Will this medicine make me urinate more?
Yes, hydrochlorothiazide is a diuretic and increases urination, particularly in the first few weeks of treatment. This is expected, but tell your doctor if you feel excessively dehydrated or dizzy.
What should I do if I miss a dose of Irbemac H 300/12.5 Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Can I buy Irbemac H 300/12.5 Tablet from DoctorOnCall?
Yes, Irbemac H 300/12.5 Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Irbemac H 300/12.5 Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Irbemac H 300/12.5 Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Irbemac H 300/12.5 Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Irbemac H 300/12.5 Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Irbemac H 300/12.5 Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Irbesartan 300mg
- Hydrochlorothiazide 12.5mg
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
