Lodoz 2.5/6.25mg Tablet
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Overview
Lodoz 2.5/6.25mg Tablet is a prescription-only medicine (POM) that contains Bisoprolol / Hydrochlorothiazide 2.5mg/6.25mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.
Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.
On DoctorOnCall, Lodoz 2.5/6.25mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.
Directions for Use
Take Lodoz 2.5/6.25mg Tablet once daily in the morning, with or without food, at about the same time each day, to avoid the increased urination from the diuretic component disturbing your sleep. Swallow the tablet whole with a glass of water. Do not stop this medicine abruptly, as suddenly stopping a beta-blocker can trigger a rebound rise in heart rate, blood pressure, or chest pain – your doctor will taper the dose gradually if it needs to be discontinued.
Dosage
Lodoz 2.5/6.25mg Tablet is usually taken once daily in the morning, at the strength your doctor has determined is right for your blood pressure control. Your doctor will periodically review your response, blood pressure readings, and blood electrolyte and kidney function tests while you are on this combination.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Dizziness or light-headedness
- Increased urination
- Headache
- Nausea or vomiting
- Muscle cramps or weakness
- Sensitivity to sunlight
Contraindications
- Known hypersensitivity to bisoprolol, hydrochlorothiazide, other sulfonamide-derived medicines, or any ingredient in this product
- Severe bradycardia (very slow heart rate) or high-degree heart block without a pacemaker
- Decompensated heart failure or cardiogenic shock
- Severe asthma or bronchospastic lung disease
- Anuria (inability to produce urine) or severe, uncorrected low blood potassium/sodium
Drug / Food Interactions
- Verapamil or diltiazem combined with bisoprolol can cause severe bradycardia or heart block
- NSAIDs may reduce the blood-pressure-lowering effect of both components
- Lithium levels may rise when combined with hydrochlorothiazide, increasing toxicity risk
- Digoxin toxicity risk increases if hydrochlorothiazide causes low blood potassium
Quick Tips
- Take your dose in the morning to reduce night-time trips to the bathroom
- Do not stop this medicine suddenly – your doctor will reduce the dose gradually if it needs to be stopped
- Rise slowly from sitting or lying down to reduce light-headedness
- Attend scheduled blood tests to monitor your kidney function and electrolytes
Frequently Asked Questions
Is Lodoz 2.5/6.25mg Tablet a prescription medicine?
Yes. Lodoz 2.5/6.25mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Lodoz 2.5/6.25mg Tablet contain?
Lodoz 2.5/6.25mg Tablet is supplied as a tablet and contains Bisoprolol / Hydrochlorothiazide 2.5mg/6.25mg. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Lodoz 2.5/6.25mg Tablet is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Lodoz 2.5/6.25mg Tablet?
Follow your doctor’s instructions and the directions on the dispensing label without changing them. If anything on the label is unclear, check with your pharmacist before taking the first dose, and read the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Lodoz 2.5/6.25mg Tablet?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Lodoz 2.5/6.25mg Tablet on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Lodoz 2.5/6.25mg Tablet?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Lodoz 2.5/6.25mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Lodoz 2.5/6.25mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Bisoprolol / Hydrochlorothiazide 2.5mg/6.25mg
Safety Advice
Pregnancy
There is no adequate data on use during pregnancy. Consult a doctor before use.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
