Onchofin 250mg Tablet
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- Muslim-Friendly
- FDA Approved
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Prescription Required
Overview
Onchofin 250mg Tablet contains terbinafine 250mg, an allylamine-class oral antifungal medicine used to treat fungal infections of the nails (onychomycosis) and certain skin fungal infections that have not responded adequately to topical treatment.
Terbinafine works by blocking an enzyme called squalene epoxidase that fungi need to build their cell membrane, which is directly toxic to the fungus and leads to its death.
How it Works
By inhibiting squalene epoxidase, terbinafine causes squalene to accumulate inside the fungal cell to toxic levels while starving the cell of ergosterol, the sterol that fungal cell membranes depend on for structural integrity – this dual effect makes terbinafine fungicidal against most dermatophytes. After oral dosing, terbinafine is absorbed and distributed into skin, hair, and nail tissue, where it accumulates and persists at effective concentrations for weeks after the tablets are stopped, which is why visible improvement in a nail infection continues even after the treatment course ends and as the nail grows out.
Directions for Use
Take Onchofin 250mg Tablet at about the same time each day, with or without food, swallowing the tablet whole with a glass of water. Continue for the full duration prescribed by your doctor, even though visible improvement in a nail infection is often slow, since the medicine needs time to clear the infection as the nail grows out.
Dosage
The usual adult dose of Onchofin 250mg Tablet is one tablet (250mg) once daily. Treatment courses are typically several weeks for skin infections and considerably longer – often several months – for nail infections, as your doctor will advise based on which nail is affected and how quickly it is growing; do not stop the course early without checking with your doctor, as this is a course-based treatment rather than an as-needed one.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Nausea or upset stomach
- Diarrhoea
- Skin rash or itching
- Taste changes or loss of taste
- Abnormal liver function tests
- Fatigue
- Muscle or joint pain
Contraindications
- Known hypersensitivity to terbinafine or any ingredient in this product
- Active or chronic liver disease
- Severe kidney impairment (dose adjustment or avoidance may be needed)
Drug / Food Interactions
- Terbinafine can increase blood levels of medicines metabolised by the liver enzyme CYP2D6, such as certain antidepressants (e.g. tricyclic antidepressants), beta-blockers, and antipsychotics
- Rifampicin can reduce terbinafine’s blood levels and effectiveness
- Cimetidine can increase terbinafine’s blood levels
- Inform your doctor of all medicines you are taking, as well as any history of liver disease, before starting treatment
Quick Tips
- Your doctor may check your liver function with a blood test before you start treatment and periodically during longer courses, since oral terbinafine can rarely affect the liver
- Report any yellowing of the skin/eyes, dark urine, or unusual tiredness to your doctor promptly
- Continue the full prescribed course even if visible improvement seems slow, especially for nail infections
- Taste changes usually resolve after the course is completed
- Avoid alcohol or use it only in moderation, as it may add to the burden on the liver during treatment
- Keep all follow-up appointments so your doctor can assess your response and check for side effects
Frequently Asked Questions
What is Onchofin 250mg Tablet used for?
Onchofin 250mg Tablet is used to treat fungal infections of the nails and certain fungal skin infections that have not responded adequately to topical treatment.
Why does treatment take so long for a nail infection?
A healthy nail must grow out fully to replace the infected part, which can take several months, especially for toenails. Terbinafine continues to act in the nail even after the tablets are stopped, so visible improvement often lags behind the end of treatment.
Do I need blood tests during treatment?
Your doctor may check your liver function before starting and periodically during longer courses, as oral terbinafine can rarely affect the liver. Report any yellowing of the skin/eyes, dark urine, or unusual tiredness promptly.
Can I drink alcohol while taking this medicine?
It is best to avoid alcohol or keep it to a minimum, as both alcohol and terbinafine are processed by the liver, and combining them may add to the burden on the liver during treatment.
What should I do if I miss a dose of Onchofin 250mg Tablet?
Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue your regular schedule. Do not double the dose.
Why has my sense of taste changed since starting this medicine?
Taste disturbance is a recognised side effect of terbinafine and is usually reversible once the course of treatment is completed. Speak to your doctor if it is severe or does not improve after stopping the medicine.
Can I buy Onchofin 250mg Tablet from DoctorOnCall?
Yes, Onchofin 250mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Onchofin 250mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Onchofin 250mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Onchofin 250mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Onchofin 250mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Onchofin 250mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Terbinafine 250mg (as terbinafine hydrochloride)
Safety Advice
Pregnancy
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use only if prescribed, with possible monitoring of kidney function.
Liver
Not recommended in patients with liver disease.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
It is not advisable to drive if you experience side effects from this medicine.
Medical Review
