Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Pharmaniaga Safrosyn S 275mg Tablet is a tablet with Naproxen sodium 275mg – active NSAID ingredient declared as its active content. It is supplied in a pack size of 10s.
This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.
An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.
Directions for Use
Take Safrosyn S 275mg Tablet exactly as advised by your doctor, swallowing it whole with a full glass of water, preferably with or shortly after a meal or snack to reduce the chance of stomach discomfort. Avoid lying down straight after taking the tablet, and do not take it on a completely empty stomach unless your doctor has specifically told you it is fine to do so.
Dosage
The dose and how often you take it will be set by your doctor based on the type and severity of your pain, with this 275mg strength commonly used as an initial or maintenance dose for mild to moderate symptoms. Do not take more tablets or take them more often than prescribed, and use the lowest dose that controls your symptoms for the shortest duration necessary.
Shelf Life
Use this medicine before the expiry date printed on the blister strip or outer carton. Discard any tablets that are past their expiry date or that have been damaged, discoloured, or exposed to moisture, rather than continuing to use them.
Storage Instructions
Store below 30°C in a cool, dry place away from direct sunlight and moisture, keeping tablets sealed in their original blister strip until you are ready to take them. Keep this medicine out of the reach and sight of children at all times.
Side Effects
Upset stomach or heartburn
Headache or dizziness
Nausea or vomiting
Drowsiness or tiredness
Constipation or diarrhea
Mild skin rash
Contraindications
Known hypersensitivity to naproxen, aspirin, or other NSAIDs, including a history of asthma, hives, or allergic reactions triggered by these medicines
Active or recurrent peptic ulcer disease or gastrointestinal bleeding
Severe heart failure
Severe kidney or liver impairment
Third trimester of pregnancy
Drug / Food Interactions
Combining with other NSAIDs or aspirin increases the risk of stomach irritation, ulcers, and bleeding
Blood thinners such as warfarin have an increased bleeding risk when taken with naproxen
Blood pressure medicines such as ACE inhibitors, ARBs, or diuretics may work less well and pose greater kidney risk when combined with naproxen
Corticosteroids taken together with naproxen further increase the risk of stomach ulcers
Methotrexate and lithium levels may rise to unsafe levels if taken with naproxen
Alcohol can increase the risk of stomach irritation when taken alongside this medicine
Quick Tips
Take with food to reduce the chance of stomach upset
Do not exceed the dose or duration prescribed by your doctor, even for mild symptoms
Avoid taking other NSAIDs, aspirin, or excessive alcohol while on this medicine
Watch for and report any signs of stomach bleeding, such as black stools or persistent stomach pain
Tell your doctor about any existing heart, kidney, liver, or stomach conditions before starting
Do not share this medicine with others even if their symptoms seem similar
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Use With Care
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Not Advisable
It is not advisable to consume alcohol while taking this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Although 275mg is the lower of the two Safrosyn S strengths, this brand is specifically labelled by its manufacturer as requiring a doctor’s prescription in Malaysia, so it should not be self-purchased or self-adjusted without medical guidance even for seemingly mild pain. Anyone with a history of stomach ulcers, heart disease, kidney disease, or who is elderly should be assessed carefully before starting, and should seek prompt medical attention if symptoms such as severe stomach pain, black stools, chest pain, or unexplained swelling occur while taking it.
Frequently Asked Questions
No. Pharmaniaga Safrosyn S 275mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Pharmaniaga Safrosyn S 275mg Tablet is a tablet containing Naproxen sodium 275mg – active NSAID ingredient. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 10s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store below 30°C in a cool, dry place away from direct sunlight and moisture, keeping tablets sealed in their original blister strip until you are ready to take them. Keep this medicine out of the reach and sight of children at all times. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
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Important Medical Information
💊 Recommended Dosage:
The dose and how often you take it will be set by your doctor based on the type and severity of your pain, with this 275mg strength commonly used as an initial or maintenance dose for mild to moderate symptoms. Do not take more tablets or take them more often than prescribed, and use the lowest dose that controls your symptoms for the shortest duration necessary.
🛑 Contraindications (Do not use if):
Known hypersensitivity to naproxen, aspirin, or other NSAIDs, including a history of asthma, hives, or allergic reactions triggered by these medicines
Active or recurrent peptic ulcer disease or gastrointestinal bleeding
Severe heart failure
Severe kidney or liver impairment
Third trimester of pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Upset stomach or heartburn
Headache or dizziness
Nausea or vomiting
Drowsiness or tiredness
Constipation or diarrhea
Mild skin rash
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.