Pharmaniaga Safrosyn S 275mg Tablet

Manufacturer Pharmaniaga
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Pharmaniaga Safrosyn S 275mg Tablet is a tablet with Naproxen sodium 275mg – active NSAID ingredient declared as its active content. It is supplied in a pack size of 10s.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Take Safrosyn S 275mg Tablet exactly as advised by your doctor, swallowing it whole with a full glass of water, preferably with or shortly after a meal or snack to reduce the chance of stomach discomfort. Avoid lying down straight after taking the tablet, and do not take it on a completely empty stomach unless your doctor has specifically told you it is fine to do so.

Dosage

The dose and how often you take it will be set by your doctor based on the type and severity of your pain, with this 275mg strength commonly used as an initial or maintenance dose for mild to moderate symptoms. Do not take more tablets or take them more often than prescribed, and use the lowest dose that controls your symptoms for the shortest duration necessary.

Shelf Life

Use this medicine before the expiry date printed on the blister strip or outer carton. Discard any tablets that are past their expiry date or that have been damaged, discoloured, or exposed to moisture, rather than continuing to use them.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight and moisture, keeping tablets sealed in their original blister strip until you are ready to take them. Keep this medicine out of the reach and sight of children at all times.

Side Effects

  • Upset stomach or heartburn
  • Headache or dizziness
  • Nausea or vomiting
  • Drowsiness or tiredness
  • Constipation or diarrhea
  • Mild skin rash

Contraindications

  • Known hypersensitivity to naproxen, aspirin, or other NSAIDs, including a history of asthma, hives, or allergic reactions triggered by these medicines
  • Active or recurrent peptic ulcer disease or gastrointestinal bleeding
  • Severe heart failure
  • Severe kidney or liver impairment
  • Third trimester of pregnancy

Drug / Food Interactions

  • Combining with other NSAIDs or aspirin increases the risk of stomach irritation, ulcers, and bleeding
  • Blood thinners such as warfarin have an increased bleeding risk when taken with naproxen
  • Blood pressure medicines such as ACE inhibitors, ARBs, or diuretics may work less well and pose greater kidney risk when combined with naproxen
  • Corticosteroids taken together with naproxen further increase the risk of stomach ulcers
  • Methotrexate and lithium levels may rise to unsafe levels if taken with naproxen
  • Alcohol can increase the risk of stomach irritation when taken alongside this medicine

Quick Tips

  • Take with food to reduce the chance of stomach upset
  • Do not exceed the dose or duration prescribed by your doctor, even for mild symptoms
  • Avoid taking other NSAIDs, aspirin, or excessive alcohol while on this medicine
  • Watch for and report any signs of stomach bleeding, such as black stools or persistent stomach pain
  • Tell your doctor about any existing heart, kidney, liver, or stomach conditions before starting
  • Do not share this medicine with others even if their symptoms seem similar

Ingredients / Active Ingredients

  • Naproxen sodium 275mg - active NSAID ingredient
  • Other pharmaceutical excipients as per manufacturer's formulation

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Although 275mg is the lower of the two Safrosyn S strengths, this brand is specifically labelled by its manufacturer as requiring a doctor’s prescription in Malaysia, so it should not be self-purchased or self-adjusted without medical guidance even for seemingly mild pain. Anyone with a history of stomach ulcers, heart disease, kidney disease, or who is elderly should be assessed carefully before starting, and should seek prompt medical attention if symptoms such as severe stomach pain, black stools, chest pain, or unexplained swelling occur while taking it.

Frequently Asked Questions

Product Specifications

BrandPharmaniaga
ManufacturerPharmaniaga
ClassificationNon-prescription
Ingredients / Active IngredientsNaproxen Sodium
Pack Size10s

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Important Medical Information

💊 Recommended Dosage:

The dose and how often you take it will be set by your doctor based on the type and severity of your pain, with this 275mg strength commonly used as an initial or maintenance dose for mild to moderate symptoms. Do not take more tablets or take them more often than prescribed, and use the lowest dose that controls your symptoms for the shortest duration necessary.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to naproxen, aspirin, or other NSAIDs, including a history of asthma, hives, or allergic reactions triggered by these medicines
  • Active or recurrent peptic ulcer disease or gastrointestinal bleeding
  • Severe heart failure
  • Severe kidney or liver impairment
  • Third trimester of pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Upset stomach or heartburn
  • Headache or dizziness
  • Nausea or vomiting
  • Drowsiness or tiredness
  • Constipation or diarrhea
  • Mild skin rash
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.