Pharmaniaga Safrosyn S 550mg Tablet

Pharmaniaga Safrosyn S 550mg Tablet is supplied as a tablet, with Naproxen sodium 550mg – active NSAID ingredient. It is supplied in a pack size of 10s.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Take Safrosyn S 550mg Tablet exactly as prescribed by your doctor, swallowing the tablet whole with a full glass of water, preferably with or after food or milk to reduce the risk of stomach irritation. Do not crush or chew the tablet unless your doctor specifically advises this, and do not lie down immediately after taking it.

The dose and frequency prescribed depend on the condition being treated and the individual patient’s response, and this higher-strength 550mg tablet is generally reserved for moderate to severe pain once lower doses have proven insufficient. Always follow your doctor’s specific instructions on dose and duration, take the lowest effective dose for the shortest time needed, and do not adjust the dose yourself without medical advice.

Use this medicine before the expiry date printed on the blister strip or carton. Do not use tablets beyond the stated expiry date, and dispose of any unused or expired tablets responsibly rather than keeping them for later use.

Store below 30°C in a cool, dry place away from direct sunlight and moisture, keeping tablets in their original blister packaging until ready to use. Keep out of the reach and sight of children at all times.

• Stomach pain, indigestion, heartburn, or nausea
• Increased risk of stomach or intestinal ulcers and bleeding, especially with prolonged use
• Headache or dizziness
• Fluid retention or swelling of the ankles/feet
• Raised blood pressure
• Ringing in the ears (tinnitus) at higher doses
• Rare but serious risk of cardiovascular events (heart attack, stroke) with long-term or high-dose use
• Rare allergic reactions such as rash, swelling, or difficulty breathing

• Known hypersensitivity to naproxen, aspirin, or other NSAIDs, including those who have had asthma, hives, or allergic reactions triggered by these medicines
• Active or history of recurrent peptic ulcer disease or gastrointestinal bleeding
• Severe heart failure, or use around the time of coronary artery bypass graft (CABG) surgery
• Severe kidney or liver impairment
• Third trimester of pregnancy

• Other NSAIDs or aspirin taken together increase the risk of stomach bleeding and ulcers
• Blood thinners (such as warfarin) combined with naproxen increase bleeding risk significantly
• ACE inhibitors, ARBs, or diuretics used for blood pressure may have reduced effect and increased kidney risk when combined with naproxen
• Corticosteroids taken alongside naproxen further raise the risk of gastrointestinal ulceration
• Lithium and methotrexate levels in the blood may rise to unsafe levels when taken with naproxen
• Alcohol increases the risk of stomach irritation and bleeding when combined with this medicine

• Take with food or milk to reduce stomach irritation
• Do not take more than the dose your doctor has prescribed, or for longer than advised
• Avoid combining with other NSAIDs, aspirin, or alcohol unless your doctor says it is safe
• Report any black or bloody stools, persistent stomach pain, or unusual bruising to your doctor immediately
• Inform your doctor of any heart, kidney, or liver conditions before starting treatment
• Keep follow-up appointments so your doctor can monitor your response and any side effects

Safrosyn S 550mg Tablet is a higher-strength NSAID intended for short-term use at the lowest effective dose under medical supervision, given the increased risk of gastrointestinal, cardiovascular, and renal side effects associated with this dose and with prolonged NSAID use in general. Patients with existing heart disease, high blood pressure, kidney disease, or who are elderly should be monitored more closely, and anyone experiencing chest pain, sudden weakness, shortness of breath, black stools, or severe stomach pain while on this medicine should seek urgent medical attention.