Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Progynova 2mg Tablet is a tablet with Estradiol valerate 2mg declared as its active content. It is supplied in pack sizes of 28s x3 and 28s.
This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.
An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.
Directions for Use
Take Progynova 2mg Tablet exactly as prescribed by your doctor, usually one tablet daily at the same time each day, swallowed whole with water; your doctor will advise whether you are on a continuous or cyclic regimen, and if you are also prescribed a progestogen, both medicines should be taken according to the specific schedule given.
Dosage
The typical starting dose is one 2mg tablet daily, though your doctor may adjust this to a lower or higher strength depending on your symptom control and individual response, always aiming to use the lowest effective dose for the shortest duration needed to manage your symptoms.
Storage Instructions
Store Progynova 2mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children.
Side Effects
Nausea or vomiting
Breast tenderness or swelling
Headache or migraine
Bloating
Mood changes
Spotting or breakthrough bleeding
Increased risk of blood clots with long-term use
Contraindications
Known, past, or suspected breast cancer or other oestrogen-dependent cancer
Undiagnosed abnormal vaginal bleeding
Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
Active or recent arterial disease such as heart attack or stroke
Severe liver disease or liver tumours
Known or suspected pregnancy
Drug / Food Interactions
Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova 2mg Tablet
Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor
Quick Tips
Use the lowest effective dose for the shortest duration needed to control your symptoms, as advised by your doctor
Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
Do not stop or adjust your dose on your own — speak to your doctor first, especially if you experience new symptoms
Inform your doctor of any new medical conditions or medicines started while on Progynova 2mg Tablet
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Not Advisable
Generally not recommended while breastfeeding.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Not Advisable
Not recommended in patients with liver disease.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Generally Safe
This medicine is generally safe and should not impair your driving ability.
Relevant Information
Progynova 2mg Tablet is generally reserved for women with moderate-to-severe menopausal symptoms who have been assessed by a doctor to have a favourable balance of benefits and risks for hormone replacement therapy. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.
Frequently Asked Questions
No. Progynova 2mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Progynova 2mg Tablet is a tablet containing Estradiol valerate 2mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in pack sizes of 28s x3 and 28s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Progynova 2mg Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Progynova 2mg Tablet is generally stable for up to 3 to 5 years from the date of manufacture when unopened, so always check the expiry date printed on the blister strip or carton before use.
What condition or symptom are you treating with this medication?
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Important Medical Information
💊 Recommended Dosage:
The typical starting dose is one 2mg tablet daily, though your doctor may adjust this to a lower or higher strength depending on your symptom control and individual response, always aiming to use the lowest effective dose for the shortest duration needed to manage your symptoms.
🛑 Contraindications (Do not use if):
Known, past, or suspected breast cancer or other oestrogen-dependent cancer
Undiagnosed abnormal vaginal bleeding
Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
Active or recent arterial disease such as heart attack or stroke
Severe liver disease or liver tumours
Known or suspected pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Breast tenderness or swelling
Headache or migraine
Bloating
Mood changes
Spotting or breakthrough bleeding
Increased risk of blood clots with long-term use
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.