Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Key Information
What is Progynova Tablet?
Progynova Tablet is an oral hormone-based medicine manufactured by Bayer.
It is available in 1mg and 2mg strengths, with each tablet containing estradiol valerate in the amount stated on the pack. The tablets have a coated finish, and the two strengths have different tablet colours.
The product is supplied in blister packaging, with 28 tablets per pack. A larger pack containing three sets of 28 tablets is also listed for the 2mg strength on DoctorOnCall.
Check the selected variant carefully to confirm the strength and quantity before placing your order.
Is this strength right for me?
Progynova is available in 1mg and 2mg strengths. Check the strength printed on the carton and blister pack to ensure it matches the product selected.
Read the package leaflet carefully before taking the tablets. Pay particular attention to the dosage instructions, warnings and precautions.
If you have a history of blood clots, liver disease, unexplained vaginal bleeding or hormone-sensitive conditions, check with a pharmacist or healthcare professional before taking this medicine.
Do not change the dosage or combine it with other hormone medicines without appropriate professional advice.
If you are pregnant, think you may be pregnant or are breastfeeding, seek professional advice before taking Progynova.
Delivery, packaging and ordering
Select the required strength and available pack size on the DoctorOnCall product page.
Review the product details and checkout information before completing your order.
Orders are processed by a registered pharmacist in accordance with the pharmacy's procedures.
When your parcel arrives, check the product name, strength, pack quantity, batch number and expiry date.
Contact DoctorOnCall customer support if the item differs from your order or the packaging arrives damaged.
Side effects, safety and when to seek help
Progynova may cause side effects such as headache, nausea, breast tenderness, abdominal discomfort or bloating.
Before taking the tablets, review the warnings concerning blood clots, liver conditions and unusual vaginal bleeding.
Tell your pharmacist or healthcare professional about any medicines or supplements you take, particularly other hormone products, as some combinations may require additional precautions.
Get urgent medical attention for sudden chest pain, difficulty breathing, sudden severe headache, changes in vision, or pain and swelling in one leg. These may indicate a serious reaction requiring immediate assessment.
How to take your Progynova Tablet
Check the packaging. Confirm whether you have the 1mg or 2mg strength and read the accompanying leaflet before taking the first tablet.
Follow the product instructions. Take the tablets according to the directions provided with the medicine. Do not change the amount or schedule on your own.
Swallow with water. The product information states that Progynova tablets are taken orally. Follow the leaflet for the correct administration instructions.
Check before combining medicines. Tell your pharmacist about other medicines, supplements or hormone products you take. If you experience a serious or unexpected reaction, stop and seek appropriate medical advice.
Delivery & Returns
Malaysia-wide delivery
No prescription needed
Licensed pharmacy
Doctor consultation
If your order arrives damaged
Do not take Progynova if the carton is damaged, the blister foil is torn or open, or the packaging appears to have been tampered with.
Check that the product name, strength and pack quantity match your order.
Take clear photographs of the parcel, delivery label, carton and blister packaging.
Contact DoctorOnCall customer support through WhatsApp and provide your order details and photographs.
Keep the product and packaging until the support team advises you on the next steps.
Returns policy
For safety reasons, medicines may not be eligible for return or exchange once they have left the pharmacy, except where the applicable policy allows it for a verified delivery issue.
If your order arrives damaged, incomplete or incorrect, contact customer support within 24 hours of delivery. Include your order details and photographs so the team can assess the issue. Do not take the product if the blister packaging is damaged or its quality is in question.
The typical dose is one tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.
Storage Instructions
Do
Follow the storage instructions printed on the carton or package leaflet.
Keep the tablets in their original blister packaging until needed.
Store the medicine in a dry place away from excessive heat and direct sunlight.
Keep it out of reach of children.
Check the expiry date before taking a tablet.
Don't
Don’t leave the medicine in a hot car or damp area.
Don’t remove tablets from the blister well before they are needed.
Don’t take tablets that are expired or have damaged packaging.
Don’t transfer tablets into unlabelled containers.
Don’t share your medicine with another person.
Side Effects
Progynova Tablet may cause side effects in some people. These reactions can vary between individuals and may change as the body adjusts to treatment. Monitor any new or persistent symptoms and consult your healthcare professional if you have concerns.
Breast Tenderness or Swelling
The breasts may feel tender, sensitive or swollen during treatment.
Nausea or Stomach Upset
Nausea or mild stomach discomfort may occur, particularly when starting treatment.
Headache
Headaches may occur during treatment. Seek medical advice if they are severe, persistent or unusual for you.
Bloating or Fluid Retention
You may notice abdominal bloating or mild swelling caused by fluid retention.
Mood Changes
Some people may notice changes in mood or emotional well-being during treatment.
Irregular Vaginal Bleeding
Spotting or breakthrough bleeding may occur, especially during the first few months of treatment.
When to Seek Medical Advice
Contact your healthcare professional if symptoms persist, worsen or interfere with daily activities. Seek prompt medical assessment for unusual, persistent or heavy vaginal bleeding.
Seek emergency medical attention for chest pain, sudden shortness of breath, sudden vision or speech changes, or painful swelling in one leg.
This information does not replace the product leaflet or advice from a healthcare professional. Do not change or stop prescribed treatment without discussing it with your healthcare professional.
Contraindications
Known, past, or suspected breast cancer or other oestrogen-dependent cancer
Undiagnosed abnormal vaginal bleeding
Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
Active or recent arterial disease such as heart attack or stroke
Severe liver disease or liver tumours
Known or suspected pregnancy
Drug / Food Interactions
Enzyme-inducing medicines such as rifampicin, certain anticonvulsants (for example carbamazepine or phenytoin), and St John’s Wort may reduce the effectiveness of Progynova Tablet
Concurrent use with tamoxifen may reduce tamoxifen’s effectiveness and should be discussed with your doctor
Anticoagulants such as warfarin may require closer monitoring when started or stopped alongside HRT
Grapefruit juice may in some cases increase estradiol blood levels; discuss significant dietary changes with your doctor
Quick Tips
Progynova Tablet is often used as a starting or step-down dose — do not change your dose without your doctor’s guidance
Attend regular follow-up appointments, including breast checks and mammograms as recommended for your age group
Report any new, unusual, or heavy vaginal bleeding to your doctor promptly
Give the tablet a few weeks to take effect before assuming your current dose is not working, and discuss any concerns at your next review
Inform your doctor of any new medical conditions or medicines started while on Progynova Tablet
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Not Advisable
Generally not recommended while breastfeeding.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Not Advisable
Not recommended in patients with liver disease.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Generally Safe
This medicine is generally safe and should not impair your driving ability.
Relevant Information
Progynova Tablet is often the preferred starting strength for women beginning hormone replacement therapy, or a step-down option once menopausal symptoms have stabilised on a higher dose, reflecting the general principle of using the lowest effective HRT dose. Because HRT carries risks that vary with age, time since menopause, and personal health history, DoctorOnCall’s doctors review each customer individually through an online consultation and recommend appropriate monitoring, including periodic reassessment of ongoing need.
How to buy
Go to the DoctorOnCall website
Visit DoctorOnCall and search for Progynova Tablet. Choose the required strength and review the available pack sizes before adding the product to your cart.
Place your order
Check your selection, enter your delivery details and follow the checkout instructions to complete your order.
Pharmacy processing
Your order will be processed by the pharmacy in accordance with its procedures and applicable supply requirements. Check your order confirmation for updates.
Receive your delivery
When your parcel arrives, check that the packaging is intact and that the product name, strength, pack quantity and expiry date match your order. Read the accompanying leaflet before taking the tablets.
Frequently Asked Questions
No. Progynova Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Progynova Tablet is a tablet containing Estradiol valerate. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 28s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Progynova Tablet below 30°C in a dry place away from direct sunlight and moisture, and keep it out of the sight and reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Product Specifications
Brand
Progynova
Manufacturer
Bayer Weimar GmbH und Co. KG
Classification
Non-prescription
Ingredients / Active Ingredients
Oestradiol
Strength
1mg or 2mg per tablet, depending on the selected variant
Pack Size
28s, 28s x3
Shelf Life
Refer to the expiry date printed on the packaging
Dosage Form
Coated tablet
Route
Oral
Dosage
Follow the instructions supplied with the product
Frequency
Refer to the package leaflet
Pack Contents
Depends on the selected strength and pack size
Storage
Follow the instructions on the carton and package leaflet
What condition or symptom are you treating with this medication?
Please select your condition / symptom before adding to cart.
*Please select the closest match. A pharmacist may call to verify your selection before dispensing.
Important Medical Information
💊 Recommended Dosage:
The typical dose is one tablet daily, often used as a starting dose for HRT or as a maintenance dose once symptoms are controlled on a higher strength, with your doctor adjusting up or down as needed to find the lowest effective dose for the shortest duration required.
🛑 Contraindications (Do not use if):
Known, past, or suspected breast cancer or other oestrogen-dependent cancer
Undiagnosed abnormal vaginal bleeding
Current or past history of venous thromboembolism (blood clots) or a known clotting disorder
Active or recent arterial disease such as heart attack or stroke
Severe liver disease or liver tumours
Known or suspected pregnancy
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Breast tenderness or swelling
Headache or migraine
Bloating
Mood changes
Spotting or breakthrough bleeding
Increased risk of blood clots with long-term use
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.