Do I need a prescription to buy Protopic 0.1% Ointment?

No. Protopic 0.1% Ointment is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Protopic 0.1% Ointment contain?

Protopic 0.1% Ointment is an ointment containing Tacrolimus (as tacrolimus monohydrate) 0.1% w/w. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Protopic 0.1% Ointment come in?

It is supplied in a pack size of 10g. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Protopic 0.1% Ointment is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Protopic 0.1% Ointment?

Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Protopic 0.1% Ointment before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

How should I store Protopic 0.1% Ointment?

Store Protopic 0.1% Ointment below 25°C to 30°C in a dry place away from direct sunlight, and keep it out of the sight and reach of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.

What should I do if I notice side effects after using Protopic 0.1% Ointment?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Protopic 0.1% Ointment be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Protopic 0.1% Ointment registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Protopic 0.1% Ointment | tacrolimus | eczema atopic dermatitis ointment | DoctorOnCall Malaysia

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Protopic 0.1% Ointment

Brand LEO

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FDA Approved
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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: October 18, 2026

Overview

Protopic 0.1% Ointment is an ointment with Tacrolimus (as tacrolimus monohydrate) 0.1% w/w declared as its active content. It is supplied in a pack size of 10g.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Apply a thin layer of Protopic 0.1% Ointment to the affected areas of skin twice daily, gently rubbing it in until fully absorbed, and continue treatment until the skin clears; once clear, your doctor may advise reducing to a maintenance regimen of two applications per week to prevent flare-ups, and hands should be washed after application unless the hands themselves are being treated.

Dosage

The typical dose for adults and adolescents (16 years and above) is a thin layer of Protopic 0.1% Ointment applied twice daily to affected areas until clearance, with your doctor guiding any adjustment to frequency for maintenance therapy; do not apply more often or in a thicker layer than prescribed.

Storage Instructions

Store Protopic 0.1% Ointment below 25°C to 30°C in a dry place away from direct sunlight, and keep it out of the sight and reach of children.

Side Effects

Headache
Nausea or vomiting
Increased blood sugar levels
Risk of infections
Tremors or shakiness
High blood pressure
Fatigue or weakness
Skin irritation (with topical use)

Contraindications

Known hypersensitivity to tacrolimus or any other ingredient in the ointment
Use on skin with an active, untreated bacterial, viral, or fungal infection
Use under occlusive dressings or bandages unless specifically advised by your doctor
Conditions associated with a weakened immune system, or a personal history of skin malignancy, without specific doctor approval
Use on Netherton’s syndrome or other conditions with significantly impaired skin barrier, due to increased systemic absorption risk

Drug / Food Interactions

Alcohol may cause facial flushing or skin warmth when combined with Protopic 0.1% Ointment
Concurrent use of other topical treatments on the same area should only be done under medical advice
Phototherapy (UV light treatment) is not recommended while using tacrolimus, as combined use may increase skin cancer risk
Live vaccines should be discussed with your doctor before administration during treatment

Quick Tips

Apply only a thin layer — more product does not improve results and may increase side effects
Minimise sun exposure and use sunscreen or protective clothing on treated areas, as tacrolimus can increase photosensitivity
Avoid using occlusive dressings or bandages over treated skin unless directed by your doctor
Do not apply to skin with active infection until it has been treated and cleared
Attend follow-up appointments so your doctor can monitor your skin’s response and adjust the regimen as needed
Wash your hands after application unless your hands are the area being treated

Ingredients / Active Ingredients

Tacrolimus

Tacrolimus (as tacrolimus monohydrate) 0.1% w/w
White soft paraffin
Paraffin oil
Propylene carbonate and other standard ointment excipients

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Not Advisable

Generally not recommended while breastfeeding.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Relevant Information

Protopic 0.1% Ointment is intended for patients whose eczema is not adequately controlled with, or who cannot use, standard topical corticosteroids, and its steroid-free mechanism makes it particularly suited to delicate areas like the face and neck where long-term steroid use raises thinning concerns. As a prescription immunomodulator, ongoing doctor follow-up is part of safe, effective treatment, and DoctorOnCall’s doctors remain available for review through further online consultations as needed.

Frequently Asked Questions

Product Specifications

Brand	LEO
Classification	Non-prescription
Ingredients / Active Ingredients	Tacrolimus
Weight	10g
Shelf Life	Protopic 0.1% Ointment is generally stable for around 2 to 3 years from the date of manufacture when unopened, so always check the expiry date printed on the tube or carton before use.