Twynsta 40/5mg Tablet

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Twynsta 40/5mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Telmisartan 40mg and Amlodipine 5mgmg (as amlodipine besylate) as its active ingredient content.

This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.

Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.

Directions for Use

Take the tablet once daily at the same time each day, with or without food, swallowed whole with water.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Dizziness or lightheadedness
  • Swelling of the ankles or feet
  • Fatigue
  • Flushing (warmth or redness in face/skin)
  • Nausea

Contraindications

  • Known hypersensitivity to telmisartan, amlodipine, dihydropyridine calcium channel blockers, or any excipient
  • Pregnancy and breastfeeding
  • Severe liver impairment or bile duct obstruction
  • Severe low blood pressure or cardiogenic shock
  • Concurrent use with aliskiren-containing medicines in patients with diabetes or kidney impairment

Drug / Food Interactions

  • NSAIDs (such as ibuprofen) may reduce the blood pressure-lowering effect and increase the risk of kidney problems.
  • Potassium-sparing diuretics, potassium supplements, or salt substitutes containing potassium may increase blood potassium levels when combined with telmisartan.
  • Grapefruit juice may increase amlodipine levels and should be used cautiously.
  • Inform your doctor of all medicines you are taking, including other blood pressure medicines.

Quick Tips

  • Rise slowly from sitting or lying positions, especially when starting treatment, to reduce dizziness.
  • Monitor your blood pressure regularly as advised by your doctor.
  • Report new or worsening ankle swelling to your doctor.
  • Do not stop this medicine suddenly without consulting your doctor.

Ingredients / Active Ingredients

  • Telmisartan 40mg
  • Amlodipine 5mgmg (as amlodipine besylate)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandBoehringer Ingelheim
ManufacturerBoehringer Ingelheim
ClassificationPrescription medicine
Ingredients / Active IngredientsAmlodipine
Pack Size30s, 30s x3
DosageThe usual dose is one 40/5mgmg tablet taken once daily. Your doctor will determine the appropriate strength based on your blood pressure response and any other medicines you are taking.
Shelf LifeRefer to the expiry date printed on the packaging.

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