Uphadyl Forte Expectorant

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Manufacturer Duopharma
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Uphadyl Forte Expectorant is a prescription-only medicine (POM) that contains Diphenhydramine hydrochloride 14mg/5ml and Ammonium chloride 135mg/5ml. It is supplied as a medicine and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Uphadyl Forte Expectorant is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Shake the bottle well before use and measure the dose accurately using the measuring cup or spoon provided, not a regular household spoon. May be taken with or without food.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Discard any unused syrup after the period stated on the label once opened.

Side Effects

  • Nausea or vomiting
  • Abdominal discomfort
  • Headache
  • Fatigue or weakness
  • Irritability or confusion (with high doses)
  • Metabolic acidosis (in rare or prolonged cases)

Contraindications

  • Known hypersensitivity to diphenhydramine, ammonium chloride, or any other ingredient
  • Severe liver or kidney impairment
  • Newborn or premature infants
  • Concurrent use with other sedating antihistamines or cough-and-cold products containing similar ingredients, due to the risk of excessive sedation

Drug / Food Interactions

  • Other sedating medicines, such as sleeping tablets, sedatives, or alcohol: combined use increases drowsiness and sedation.
  • Monoamine oxidase inhibitors (MAOIs): may prolong and intensify the antihistamine effect of diphenhydramine.
  • Other cough and cold products: check ingredients before combining to avoid duplicate doses of diphenhydramine or similar antihistamines.
  • Inform your doctor or pharmacist of all medicines your child or you are taking before starting this syrup.

Quick Tips

  • Avoid driving or operating machinery after taking this medicine, as it can cause drowsiness.
  • Drink plenty of fluids while taking this medicine, as adequate hydration helps the expectorant loosen mucus more effectively.
  • Do not combine with other cough, cold, or allergy products without checking with a pharmacist, to avoid taking too much of the same ingredient.
  • See a doctor if the cough persists beyond a week, worsens, or is accompanied by fever, breathlessness, or coughing up blood.

Ingredients / Active Ingredients

  • Diphenhydramine hydrochloride 14mg/5ml
  • Ammonium chloride 135mg/5ml

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Not Advisable

Not generally recommended in patients with kidney disease.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandDuopharma
ManufacturerDuopharma
ClassificationPrescription medicine
Ingredients / Active IngredientsAmmonium Chloride
Volume90ml
DosageThe dose depends on age and is prescribed by your doctor, typically given two to three times a day using the measuring device provided; do not exceed the dose or duration advised.
Shelf LifeRefer to the expiry date printed on the packaging.

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