Vivere 5% cream

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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Vivere 5% cream is supplied as a cream, with Acyclovir (aciclovir) 5%. It is supplied in a pack size of 5g.

No prescription is required for this product, as it is a non-prescription medicine. This page is limited to product, safety and handling information.

If you would like guidance before buying, you can speak to a doctor or pharmacist through an online consultation on DoctorOnCall. Orders are dispensed by a registered pharmacist and delivered to your address.

Directions for Use

Wash and dry your hands, then apply a small amount of Vivere 5% Cream to the affected area at the earliest sign of a cold sore, such as tingling or itching, and continue applying five times a day at roughly four-hourly intervals (skipping the night-time application) for four to five days. Wash your hands again after application to avoid spreading the virus to other areas of your face or to other people, and avoid sharing lip balm, cups or towels while a sore is present.

Dosage

The typical adult and adolescent dose is a thin application of Vivere 5% Cream to the affected lip or perioral area five times daily, about every four hours, for five consecutive days; if the cold sore has not healed by then, treatment should not simply be extended without checking with a pharmacist or doctor. Use in young children should be guided by a pharmacist or doctor.

Storage Instructions

Store below 25°C in a cool, dry place away from direct sunlight, and keep the tube tightly closed after each use to prevent it from drying out. Keep out of the reach and sight of children.

Side Effects

  • Nausea or vomiting
  • Headache
  • Dizziness
  • Diarrhoea
  • Joint or muscle pain
  • Fatigue or tiredness
  • Mild rash or skin reaction

Contraindications

  • Known allergy or hypersensitivity to acyclovir, valacyclovir, or any ingredient in the cream
  • Use inside the mouth, on the gums, or near the eyes
  • Genital herpes lesions, which need a doctor’s assessment rather than a lip-cream product
  • Individuals with significantly weakened immune systems, who should seek medical advice first

Drug / Food Interactions

  • No clinically significant drug interactions are expected with normal topical use, as absorption into the bloodstream is minimal
  • Avoid applying other topical products to the same area at the same time, as this may dilute the cream or irritate already inflamed skin
  • Consult a pharmacist if you are using other prescribed topical or oral antiviral treatments

Quick Tips

  • Apply at the very first tingling or itching sensation for the best chance of stopping the sore from progressing
  • Use a clean cotton bud or washed fingertip to apply the cream to reduce the risk of spreading the virus
  • Do not share lip balm, cutlery, cups or towels while you have an active cold sore
  • Avoid kissing or close facial contact with others, especially babies and those who are immunocompromised, until the sore has healed
  • See a pharmacist or doctor if cold sores are frequent, severe, or do not improve within a few days of starting treatment

Ingredients / Active Ingredients

  • Acyclovir (aciclovir) 5% (active ingredient)
  • Cream base containing emulsifying and moisturising agents
  • Other pharmaceutical excipients as per the manufacturer's formulation

Safety Advice

Pregnancy

Safe If Prescribed

This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Generally Safe

Consuming alcohol with this medicine is generally safe, but moderate intake is advised.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Cold sores are contagious from the moment tingling begins until the blister has fully crusted over and healed, so good hand hygiene and avoiding direct contact with others during this period is important. Vivere 5% Cream treats the current outbreak but does not cure the underlying herpes simplex virus, which remains dormant in the body and can reactivate; triggers such as sunlight, stress, fever, and hormonal changes can bring on future episodes, and keeping a small supply of cream on hand allows treatment to start as early as possible.

Frequently Asked Questions

Product Specifications

ClassificationNon-prescription
Ingredients / Active IngredientsAcyclovir
Weight5g
Shelf LifeWhen stored correctly and unopened, Vivere 5% Cream is generally stable until the expiry date printed on the tube and carton; the expiry date should be checked before each use and expired cream should be discarded.

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Important Medical Information

💊 Recommended Dosage:

The typical adult and adolescent dose is a thin application of Vivere 5% Cream to the affected lip or perioral area five times daily, about every four hours, for five consecutive days; if the cold sore has not healed by then, treatment should not simply be extended without checking with a pharmacist or doctor. Use in young children should be guided by a pharmacist or doctor.

🛑 Contraindications (Do not use if):
  • Known allergy or hypersensitivity to acyclovir, valacyclovir, or any ingredient in the cream
  • Use inside the mouth, on the gums, or near the eyes
  • Genital herpes lesions, which need a doctor’s assessment rather than a lip-cream product
  • Individuals with significantly weakened immune systems, who should seek medical advice first
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Headache
  • Dizziness
  • Diarrhoea
  • Joint or muscle pain
  • Fatigue or tiredness
  • Mild rash or skin reaction
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.