Vytorin 10/40 mg Tablet
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Prescription Required
Overview
Vytorin 10/40 mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Ezetimibe 10mg and Simvastatin 40mg as its active ingredient content.
This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.
Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.
Directions for Use
Take Vytorin 10/40 mg Tablet once daily in the evening, with or without food, and swallow the tablet whole with a glass of water. Taking it consistently at the same time each evening helps maintain steady cholesterol control, since cholesterol production is normally highest overnight.
Dosage
Vytorin 10/40 mg Tablet is usually taken as one tablet once daily in the evening, as instructed by your doctor. The specific strength prescribed is based on your cholesterol levels, cardiovascular risk, and response to previous cholesterol-lowering treatment, and should not be changed without medical advice.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Headache
- Diarrhea
- Joint pain
- Fatigue
- Stomach pain
- Cough or respiratory issues
- Dizziness
- Elevated liver enzymes (when combined with statins)
Contraindications
- Known hypersensitivity to ezetimibe, simvastatin, or any ingredient in this product
- Active liver disease or unexplained persistent elevation of liver enzymes
- Pregnancy and breastfeeding
- Concomitant use with strong CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, certain HIV protease inhibitors, clarithromycin)
- Concomitant use with gemfibrozil or ciclosporin
Drug / Food Interactions
- Strong CYP3A4 inhibitors (e.g. itraconazole, clarithromycin, HIV protease inhibitors) significantly increase simvastatin levels and the risk of muscle toxicity
- Grapefruit juice can raise simvastatin blood levels and should be avoided or limited
- Gemfibrozil and other fibrates increase the risk of muscle-related side effects when combined
- Warfarin’s blood-thinning effect may be enhanced, requiring closer INR monitoring
Quick Tips
- Take in the evening at the same time each day for consistent effect
- Report unexplained muscle pain, tenderness, or weakness to your doctor promptly
- Avoid or strictly limit grapefruit juice while taking this medicine
- Attend scheduled blood tests to monitor cholesterol and liver function
- Continue taking this medicine even if your cholesterol improves, unless your doctor advises otherwise
Frequently Asked Questions
Is Vytorin 10/40 mg Tablet a prescription medicine?
Yes. Vytorin 10/40 mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Vytorin 10/40 mg Tablet contain?
Vytorin 10/40 mg Tablet is supplied as a tablet and contains Ezetimibe 10mg and Simvastatin 40mg. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Vytorin 10/40 mg Tablet is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Vytorin 10/40 mg Tablet?
Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Vytorin 10/40 mg Tablet?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Vytorin 10/40 mg Tablet on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Vytorin 10/40 mg Tablet?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Vytorin 10/40 mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Vytorin 10/40 mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Ezetimibe 10mg
- Simvastatin 40mg
Safety Advice
Pregnancy
Limited information is available regarding use during pregnancy. Use only if clearly needed.
Breastfeeding
Limited data on excretion in breast milk. Consult a doctor before use.
Kidney
Generally safe, but caution may be required in some patients.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
Caution is advised when consuming alcohol with this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
Medical Review
