Letimble 10mg Tablet

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Overview

Letimble 10mg Tablet contains ezetimibe 10mg, a cholesterol absorption inhibitor used to lower high cholesterol. It is used either on its own, or together with a statin, in patients whose LDL (“bad”) cholesterol is not adequately controlled by diet and a statin alone.

Ezetimibe works at the brush border of the small intestine, where it blocks the absorption of cholesterol from food and from bile. This reduces the amount of cholesterol delivered to the liver, which prompts the liver to clear more LDL cholesterol from the bloodstream, lowering overall cholesterol levels.

How it Works

Ezetimibe selectively blocks a transporter protein (NPC1L1) on the surface of intestinal cells, preventing dietary and biliary cholesterol from being absorbed into the bloodstream. With less cholesterol arriving from the gut, the liver increases its uptake of LDL cholesterol from the blood to make up the shortfall, lowering circulating LDL levels.

Directions for Use

Take Letimble 10mg Tablet once daily, with or without food, at about the same time each day. Swallow the tablet whole with a glass of water. If your doctor has also prescribed a statin, ezetimibe can usually be taken at the same time, unless you have also been prescribed a bile acid sequestrant (such as cholestyramine), in which case ezetimibe should be taken at least 2 hours before or 4 hours after it.

Dosage

The usual dose of Letimble 10mg Tablet is one tablet once daily, taken alone or together with a statin as prescribed. Your doctor will determine whether ezetimibe is used on its own or combined with a statin, and will periodically check your cholesterol levels and liver function to guide ongoing treatment.

Shelf Life

Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Headache
  • Diarrhea
  • Joint pain
  • Fatigue
  • Stomach pain
  • Cough or respiratory issues
  • Dizziness
  • Elevated liver enzymes (when combined with statins)

Contraindications

  • Known hypersensitivity to ezetimibe or any ingredient in this product
  • Active liver disease or unexplained persistent elevation of liver enzymes, when ezetimibe is combined with a statin
  • Pregnancy and breastfeeding, when combined with a statin
  • Moderate to severe liver impairment

Drug / Food Interactions

  • Cyclosporine can significantly increase ezetimibe blood levels, requiring closer monitoring
  • Fibrates, particularly gemfibrozil, may increase the risk of gallstones and muscle-related side effects when combined
  • Cholestyramine and other bile acid sequestrants reduce ezetimibe absorption if taken at the same time – space doses apart as advised
  • Warfarin’s blood-thinning effect may occasionally be affected, so INR should be monitored if you take both

Quick Tips

  • Take at the same time every day to build a routine
  • Continue any statin exactly as prescribed alongside ezetimibe unless your doctor tells you otherwise
  • Attend scheduled blood tests to monitor cholesterol and liver function
  • Report any unexplained muscle pain or weakness to your doctor promptly, especially if you also take a statin
  • Maintain a cholesterol-friendly diet and stay physically active alongside your medicine
  • Do not stop this medicine without consulting your doctor, even if your cholesterol improves

Frequently Asked Questions

What is Letimble 10mg Tablet used for?

Letimble 10mg Tablet is used to lower high LDL (“bad”) cholesterol, either on its own or together with a statin, when diet and other cholesterol medicines have not fully controlled it.

Is ezetimibe a statin?

No. Ezetimibe is a cholesterol absorption inhibitor, a different class of medicine from statins. It blocks cholesterol absorption in the gut rather than reducing cholesterol production in the liver, which is why it is often used together with a statin for additional effect.

Can I take this medicine together with my statin?

Yes, ezetimibe is commonly prescribed together with a statin, and this combination is often more effective at lowering LDL cholesterol than either medicine alone. Take both exactly as directed by your doctor.

How long does it take to see a change in my cholesterol?

Ezetimibe typically starts lowering cholesterol within about 2 weeks, with the full effect usually seen after around 4 weeks of regular use.

What should I do if I miss a dose of Letimble 10mg Tablet?

Take the missed dose as soon as you remember, unless it is almost time for your next dose – in that case, skip the missed dose and continue as normal. Do not double the dose.

Do I still need to watch my diet if I am taking this medicine?

Yes. Ezetimibe works best alongside a cholesterol-lowering diet and regular exercise; it is not a substitute for lifestyle changes recommended by your doctor.

Can I buy Letimble 10mg Tablet from DoctorOnCall?

Yes, Letimble 10mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.

Is the medication provided by DoctorOnCall genuine and safe to use?

DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Letimble 10mg Tablet according to your doctor’s instructions and the information provided with the product.

What payment methods does DoctorOnCall accept?

We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.

Does DoctorOnCall provide an installment payment plan for Letimble 10mg Tablet?

DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.

Is delivery free, and how much does shipping for Letimble 10mg Tablet cost?

Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.

How long does delivery take for Letimble 10mg Tablet?

Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.

What is DoctorOnCall’s shipping, return, or cancellation policy for Letimble 10mg Tablet?

Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.

Ingredients / Active Ingredients

  • Ezetimibe 10mg

Safety Advice

Pregnancy

Limited Data

Limited information is available regarding use during pregnancy. Use only if clearly needed.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Generally Safe

Generally safe, but caution may be required in some patients.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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