Xepa Ezede-D Oral Solution

Brand Xepa
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Xepa Ezede-D Oral Solution is a solution with Cetirizine Dihydrochloride and Pseudoephedrine Hydrochloride declared as its active content. It is supplied in a pack size of 60ml.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Shake the bottle if instructed on the label, and measure the dose accurately using the measuring device provided rather than a household spoon. Xepa Ezede-D Oral Solution can be taken with or without food; however, because the pseudoephedrine component can be stimulating, avoid taking a dose too close to bedtime if it tends to disturb your sleep, and avoid driving or operating machinery until you know how it affects you.

Dosage

Dosing should follow the age-based directions on the product label or a pharmacist’s advice, as the combined cetirizine and pseudoephedrine content differs from plain cetirizine products and needs to be measured accurately with the device provided. This oral solution is generally intended for older children and adults, and it is not recommended for young children without specific medical advice, given the added decongestant component. Always check the exact age cut-off and dose stated on your product’s packaging before use.

Shelf Life

Unopened, Xepa Ezede-D Oral Solution is generally stable until the expiry date printed on the bottle or carton when stored correctly; once opened, it should generally be used within the period stated on the label or leaflet, so check the packaging for specific guidance.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight, keep the bottle tightly closed between uses, and do not freeze. Keep out of the reach and sight of children.

Side Effects

  • Headache
  • Dry mouth
  • Sleepiness or fatigue (less common)
  • Gastrointestinal discomfort
  • Nervousness or dizziness (rare)

Contraindications

  • Known hypersensitivity to cetirizine, pseudoephedrine, hydroxyzine, or any piperazine derivative
  • Uncontrolled or severe high blood pressure (hypertension)
  • Severe coronary artery disease or other significant heart conditions
  • Hyperthyroidism
  • Severe prostate enlargement with urinary retention
  • Use of an MAOI within the past 14 days
  • Young children, particularly below the age cut-off stated on the label, without specific medical advice
  • Severe kidney impairment without appropriate dose adjustment

Drug / Food Interactions

  • MAOIs – risk of a dangerous rise in blood pressure (hypertensive crisis); avoid combining
  • Other decongestants or stimulant medicines – additive effects on heart rate, blood pressure, and nervousness
  • Blood pressure medicines – pseudoephedrine can reduce their effectiveness or raise blood pressure
  • Caffeine – may worsen jitteriness, nervousness, or difficulty sleeping
  • Alcohol – may add to drowsiness or dizziness
  • Other cold, flu, or allergy products containing a decongestant or antihistamine – avoid combining to prevent duplicate dosing

Quick Tips

  • Avoid taking a dose too close to bedtime if it disturbs your sleep
  • Monitor your blood pressure if you have a history of hypertension, and check with a pharmacist before use
  • Avoid or limit caffeine while taking this solution to reduce jitteriness
  • Do not use alongside other decongestant-containing cold or flu products
  • Not recommended for young children — always check the age cut-off on the label
  • Speak to a doctor if symptoms don’t improve, or if you notice a fast heartbeat, chest discomfort, or severe headache

Ingredients / Active Ingredients

  • Cetirizine Dihydrochloride (active ingredient — antihistamine component)
  • Pseudoephedrine Hydrochloride (active ingredient — decongestant component)
  • Sweetening and flavouring agents
  • Preservative (e.g. a permitted antimicrobial preservative)
  • Purified water
  • Exact strengths and inactive ingredients vary by pack — always check the product packaging or leaflet for the full formulation

Safety Advice

Pregnancy

Generally Safe

This medicine is generally safe during pregnancy, though minor risks may exist in rare cases.

Breastfeeding

Use With Care

Use with caution. Monitor infant for potential adverse reactions.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Because Xepa Ezede-D Oral Solution contains pseudoephedrine in addition to cetirizine, it needs more caution than a plain antihistamine: it should be avoided by people with high blood pressure, heart disease, hyperthyroidism, or glaucoma, and it can cause insomnia, nervousness, or a fast heartbeat in some users, so it is not the best choice for evening dosing or for anyone sensitive to stimulant-type effects. It is also not intended for young children, given the decongestant component’s stronger effect on the heart and nervous system in that age group. Pregnant or breastfeeding women, the elderly, and anyone with high blood pressure, heart, thyroid, or prostate conditions should check with a pharmacist or doctor before use, and if congestion or allergy symptoms are severe or don’t improve, seek medical advice rather than continuing to self-treat.

Frequently Asked Questions

Product Specifications

BrandXepa
ClassificationNon-prescription
Ingredients / Active IngredientsLoratadine
Volume60ml

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Important Medical Information

💊 Recommended Dosage:

Dosing should follow the age-based directions on the product label or a pharmacist’s advice, as the combined cetirizine and pseudoephedrine content differs from plain cetirizine products and needs to be measured accurately with the device provided. This oral solution is generally intended for older children and adults, and it is not recommended for young children without specific medical advice, given the added decongestant component. Always check the exact age cut-off and dose stated on your product’s packaging before use.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to cetirizine, pseudoephedrine, hydroxyzine, or any piperazine derivative
  • Uncontrolled or severe high blood pressure (hypertension)
  • Severe coronary artery disease or other significant heart conditions
  • Hyperthyroidism
  • Severe prostate enlargement with urinary retention
  • Use of an MAOI within the past 14 days
  • Young children, particularly below the age cut-off stated on the label, without specific medical advice
  • Severe kidney impairment without appropriate dose adjustment
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Headache
  • Dry mouth
  • Sleepiness or fatigue (less common)
  • Gastrointestinal discomfort
  • Nervousness or dizziness (rare)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.