Janumet 50/850mg Tablet

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Brand MSD
Manufacturer MSD
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Chong Zhan Pong
Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated:

Overview

Janumet 50/850mg Tablet is a prescription-only medicine (POM) that contains Sitagliptin 50mg (as sitagliptin phosphate monohydrate) and Metformin hydrochloride 850mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.

Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.

On DoctorOnCall, Janumet 50/850mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.

Directions for Use

Take Janumet 50/850mg Tablet with food, at roughly the same times each day, and swallow the tablet whole with a glass of water without crushing or chewing it. Continue taking it regularly even if you feel well, and do not skip doses, since consistent use is needed to keep blood glucose stable throughout the day.

Dosage

The usual dose of Janumet 50/850mg Tablet is one tablet twice daily, taken with meals to reduce stomach upset, with the specific strength chosen by your doctor based on your current metformin dose and blood glucose control. Your doctor will individualise your dose and periodically check your kidney function, as the metformin component needs dose adjustment or avoidance if kidney function declines.

Storage Instructions

Store below 30°C in a dry place, away from direct sunlight and out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

  • Known hypersensitivity to sitagliptin, metformin, or any ingredient in this product
  • Severe kidney impairment
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Conditions that increase the risk of lactic acidosis, such as severe dehydration, serious infection, or significant liver impairment
  • Planned use of iodinated contrast media without a temporary treatment interruption as advised by your doctor

Drug / Food Interactions

  • Alcohol can increase the risk of lactic acidosis and low blood glucose, and should be limited
  • Iodinated contrast media used in certain X-ray or scan procedures may require temporarily stopping this medicine around the time of the procedure
  • Other diabetes medicines or insulin can increase the risk of low blood glucose when combined
  • Corticosteroids and certain diuretics may raise blood glucose and reduce this medicine’s effectiveness

Quick Tips

  • Take with meals to reduce stomach upset
  • Monitor your blood glucose as advised by your doctor and attend scheduled kidney function tests
  • Tell any doctor or radiographer that you take this medicine before any scan involving contrast dye
  • Carry a fast-acting source of sugar if you also take a sulfonylurea or insulin, in case of hypoglycaemia

Ingredients / Active Ingredients

  • Sitagliptin 50mg (as sitagliptin phosphate monohydrate)
  • Metformin hydrochloride 850mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Frequently Asked Questions

Product Specifications

BrandMSD
ManufacturerMSD
ClassificationPrescription medicine
Ingredients / Active IngredientsMetformin
Pack Size56s, 7s
Shelf LifeUse this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.

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Important Medical Information

💊 Recommended Dosage:

The usual dose of Janumet 50/850mg Tablet is one tablet twice daily, taken with meals to reduce stomach upset, with the specific strength chosen by your doctor based on your current metformin dose and blood glucose control. Your doctor will individualise your dose and periodically check your kidney function, as the metformin component needs dose adjustment or avoidance if kidney function declines.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to sitagliptin, metformin, or any ingredient in this product
  • Severe kidney impairment
  • Acute or chronic metabolic acidosis, including diabetic ketoacidosis
  • Conditions that increase the risk of lactic acidosis, such as severe dehydration, serious infection, or significant liver impairment
  • Planned use of iodinated contrast media without a temporary treatment interruption as advised by your doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.