Uphamol 500mg Tablet

Uphamol 500mg Tablet is an oral tablet containing 500mg of paracetamol (acetaminophen) as its sole active ingredient, formulated for adults and adolescents aged 12 years and above. It belongs to the non-opioid analgesic and antipyretic drug class and is registered for over-the-counter sale in Malaysia. Each tablet is supplied in strip packaging and is intended for oral administration only.

Paracetamol is one of the most extensively studied active pharmaceutical ingredients in the world and has been used in clinical practice for decades. This tablet form is not intended for children under 12 years old, for whom an age-appropriate Uphamol syrup formulation is available separately. Uphamol 500mg Tablet is manufactured to meet the quality standards required for pharmaceutical products registered in Malaysia.

Swallow the tablet whole with a glass of water. It may be taken with or without food; taking it after a meal may help if you have a sensitive stomach. Do not crush or chew the tablet unless advised by a pharmacist. Space each dose at least 4 to 6 hours apart.

Adults and children 12 years and above: 1 tablet (500mg) every 4 to 6 hours as needed, not exceeding 8 tablets (4000mg) in 24 hours. If a dose is missed, take it when remembered unless the next dose is due soon; do not take a double dose to make up for a missed one. Do not continue self-treating for more than 3 days for fever or 5 days for pain without consulting a doctor or pharmacist.

Use before the expiry date printed on the strip and outer packaging.

Store below 30°C in a dry place, away from direct sunlight and moisture, in the original packaging. Keep out of the reach and sight of children.

• Common: Nausea or mild stomach discomfort.
• Common: Skin rash in sensitive individuals.
• Serious: Signs of liver problems such as yellowing of the skin or eyes, dark urine, or unusual tiredness with prolonged high-dose use or overdose – seek urgent medical care.
• Serious: Signs of a severe allergic reaction, including swelling of the face, lips or throat, difficulty breathing, or widespread hives – seek emergency care immediately.

• Known hypersensitivity to paracetamol or any excipient in the tablet.
• Severe hepatic (liver) impairment or active severe liver disease.
• Not for use in children under 12 years old; an age-appropriate paediatric paracetamol formulation should be used instead.

• Do not take together with other medicines that already contain paracetamol, including many cold and flu combination products, to avoid exceeding the maximum daily dose.
• Regular, long-term use alongside warfarin may increase bleeding risk; patients on warfarin should seek pharmacist advice before regular use.
• Chronic heavy alcohol intake increases the risk of liver toxicity when combined with paracetamol.
• Certain anti-seizure medicines, such as phenytoin or carbamazepine, may increase the risk of liver toxicity with paracetamol; inform your pharmacist of all medicines you are taking.

• Always check the active ingredients of any other medicine before combining it with this tablet.
• Take with a full glass of water.
• Keep track of the time between doses to avoid exceeding the 24-hour limit.
• Keep the strip in its original packaging so the expiry date stays visible.
• Store out of reach and sight of children at all times.
• Bring the product packaging with you if you need to consult a doctor or pharmacist about this medicine.

Precautions: Use the lowest effective dose for the shortest time needed. People with chronic liver or kidney disease, those who consume alcohol regularly, or those who are malnourished should seek pharmacist advice before use. Pregnant or breastfeeding individuals should consult a doctor before use.

When to See a Doctor or Pharmacist: Seek professional advice if fever lasts more than 3 days, pain lasts more than 5 days, symptoms worsen, or you notice signs of an allergic reaction or liver problems such as unusual tiredness, loss of appetite, or yellowing of the skin or eyes.