Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Janumet 50/850mg Tablet is a prescription-only medicine (POM) that contains Sitagliptin 50mg (as sitagliptin phosphate monohydrate) and Metformin hydrochloride 850mg. It is supplied as a tablet and is dispensed in Malaysia only against a valid prescription issued by a registered doctor.
Under Malaysian rules for prescription medicines, this page carries product, safety and handling information only. Your doctor or pharmacist will explain whether this medicine is suitable for you, the dose you should take, and how long you should take it.
On DoctorOnCall, Janumet 50/850mg Tablet is reviewed by a licensed doctor through an online consultation and dispensed by a registered pharmacist before delivery. Always follow the instructions on your prescription label and the package insert supplied with the product, and do not share this medicine with anyone else.
Directions for Use
Take Janumet 50/850mg Tablet with food, at roughly the same times each day, and swallow the tablet whole with a glass of water without crushing or chewing it. Continue taking it regularly even if you feel well, and do not skip doses, since consistent use is needed to keep blood glucose stable throughout the day.
Dosage
The usual dose of Janumet 50/850mg Tablet is one tablet twice daily, taken with meals to reduce stomach upset, with the specific strength chosen by your doctor based on your current metformin dose and blood glucose control. Your doctor will individualise your dose and periodically check your kidney function, as the metformin component needs dose adjustment or avoidance if kidney function declines.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Contraindications
Known hypersensitivity to sitagliptin, metformin, or any ingredient in this product
Severe kidney impairment
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Conditions that increase the risk of lactic acidosis, such as severe dehydration, serious infection, or significant liver impairment
Planned use of iodinated contrast media without a temporary treatment interruption as advised by your doctor
Drug / Food Interactions
Alcohol can increase the risk of lactic acidosis and low blood glucose, and should be limited
Iodinated contrast media used in certain X-ray or scan procedures may require temporarily stopping this medicine around the time of the procedure
Other diabetes medicines or insulin can increase the risk of low blood glucose when combined
Corticosteroids and certain diuretics may raise blood glucose and reduce this medicine’s effectiveness
Quick Tips
Take with meals to reduce stomach upset
Monitor your blood glucose as advised by your doctor and attend scheduled kidney function tests
Tell any doctor or radiographer that you take this medicine before any scan involving contrast dye
Carry a fast-acting source of sugar if you also take a sulfonylurea or insulin, in case of hypoglycaemia
This medicine should be used cautiously during pregnancy. Monitoring may be required.
Breastfeeding
Generally Safe
This medicine is generally safe during breastfeeding with minimal risk to the infant.
Kidney
Use With Care
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Frequently Asked Questions
Yes. Janumet 50/850mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
Janumet 50/850mg Tablet is supplied as a tablet and contains Sitagliptin 50mg (as sitagliptin phosphate monohydrate) and Metformin hydrochloride 850mg. The full composition is listed in the Composition section on this page and on the product packaging.
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
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Important Medical Information
💊 Recommended Dosage:
The usual dose of Janumet 50/850mg Tablet is one tablet twice daily, taken with meals to reduce stomach upset, with the specific strength chosen by your doctor based on your current metformin dose and blood glucose control. Your doctor will individualise your dose and periodically check your kidney function, as the metformin component needs dose adjustment or avoidance if kidney function declines.
🛑 Contraindications (Do not use if):
Known hypersensitivity to sitagliptin, metformin, or any ingredient in this product
Severe kidney impairment
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Conditions that increase the risk of lactic acidosis, such as severe dehydration, serious infection, or significant liver impairment
Planned use of iodinated contrast media without a temporary treatment interruption as advised by your doctor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
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IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.