Kombiglyze XR 5mg/1000mg Tablet

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Prescription Required

Orders placed now will be queued. A doctor will contact you on the next working day for approval.

Overview

Kombiglyze XR 5mg/1000mg Tablet is a prescription medicine that belongs to the class known as anti-diabetic drugs, specifically a combination of a DPP-4 inhibitor and biguanide. It contains two active ingredients: saxagliptin (5mg) and metformin hydrochloride (1000mg). While taking this tablet, some people may experience side effects like nausea, headache, stomach upset, or cold-like symptoms. Before starting, it’s good to know this medicine needs to be taken regularly, preferably at the same time daily. Also, because it is an extended-release (XR) formulation, it works gradually in your system—so don’ crush or chew the tablet.

Directions for Use

Take Kombiglyze XR 5mg/1000mg Tablet once daily with food, and swallow it whole with water—do not crush or chew the tablet.

Dosage

The usual recommended dosage is one tablet once daily, but your doctor will decide the exact dose depending on your individual condition and response.

Shelf Life

The shelf life of this medication is typically 2 to 3 years from the date of manufacture; always check the expiry date on the package before use.

Storage Instructions

Store it at room temperature below 30°C, away from moisture, heat, and direct sunlight. Keep it out of reach of children.

Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)

Contraindications

Do not take Kombiglyze XR if you are allergic to saxagliptin, metformin, or any other ingredient in this medication. It is also not suitable for individuals with severe kidney problems or metabolic acidosis, including diabetic ketoacidosis.

Drug / Food Interactions

Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of lactic acidosis. Inform your doctor about all other medicines you are taking, including over-the-counter drugs and supplements, as interactions with diuretics, corticosteroids, or certain antibiotics can occur.

Quick Tips

  • Always take this medicine after food to reduce stomach discomfort
  • Swallow the tablet whole; do not chew or crush
  • Stay hydrated and follow any dietary advice provided by your healthcare provider
  • Never skip doses or stop suddenly without consulting your doctor
  • Store in a cool, dry place and keep the packaging tightly closed

Frequently Asked Questions

Is Kombiglyze XR 5mg/1000mg Tablet available online in Malaysia?

Yes, you can conveniently order Kombiglyze XR 5mg/1000mg Tablet through our trusted Malaysian online pharmacy with direct delivery to your doorstep.

Do I need a prescription to buy Kombiglyze XR 5mg/1000mg Tablet in Malaysia?

Yes, a valid prescription from a licensed healthcare provider is required to purchase Kombiglyze XR in Malaysia.

How quickly can I receive Kombiglyze XR if I order from your online store?

We offer fast and secure delivery across Malaysia, usually within 1–3 working days depending on your location.

Are the medications you sell genuine and approved for use in Malaysia?

Absolutely. All our medications, including Kombiglyze XR, are sourced from certified suppliers and comply with local regulatory standards.

Can I speak to a pharmacist before placing my order?

Yes, our licensed pharmacists are available to assist you with any questions or concerns before you make a purchase.

Is it cheaper to buy Kombiglyze XR 5mg/1000mg Tablet online compared to local pharmacies in Singapore?

Many of our customers in Singapore choose to buy from our Malaysia-based online pharmacy for better prices and reliable shipping options.

Ingredients / Active Ingredients

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Medical Review

Written by:

Dr. Chong Zhan Pong

Doctor of Medicine (MD), International Medical University (IMU)

Reviewed by:

Dr. Mohd Izzat Amir Bin Awang

Doctor of Medicine (MD), University of Mansoura - Manchester

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Important Medical Information

💊 Recommended Dosage:

The usual dose of Kombiglyze XR 5mg/1000mg Tablet is one tablet once daily, taken with the evening meal, but your doctor will individualise the exact strength and regimen based on your current metformin dose, kidney function, and blood glucose control. Do not adjust your dose without medical advice.

🛑 Contraindications (Do not use if):
  • Known hypersensitivity to saxagliptin, metformin, or any ingredient in this product
  • Severe kidney impairment or acute conditions with risk of altered kidney function (dehydration, severe infection, shock)
  • Metabolic acidosis, including diabetic ketoacidosis
  • Conditions predisposing to tissue hypoxia (e.g. decompensated heart failure, recent heart attack, respiratory failure)
  • History of a serious hypersensitivity reaction to a DPP-4 inhibitor
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
  • Nausea or vomiting
  • Diarrhea
  • Stomach discomfort or cramps
  • Metallic taste in the mouth
  • Loss of appetite
  • Weight loss (in some cases)
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.