Apo-Alendronate 70mg Tablet
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Prescription Required
Overview
Apo-Alendronate 70mg Tablet contains alendronate (alendronic acid) 70mg, a bisphosphonate used once weekly to treat and prevent osteoporosis (thinning, weakened bones) in postmenopausal women and in men at risk of fracture, as well as certain types of steroid-induced bone loss.
Alendronate works by attaching to bone surfaces and slowing down the activity of osteoclasts, the cells that break down old bone tissue. This allows bone-building cells to work more effectively relative to bone breakdown, increasing bone density over time and reducing fracture risk.
How it Works
Alendronate binds strongly to hydroxyapatite in bone and is taken up by osteoclasts during bone resorption, where it inhibits the enzyme farnesyl pyrophosphate synthase. This disrupts osteoclast function and reduces bone breakdown, shifting the balance toward bone formation and increasing bone mineral density.
Directions for Use
Take Apo-Alendronate 70mg Tablet first thing in the morning, on an empty stomach, with a full glass of plain water (not mineral water, juice, coffee, or tea) at least 30 minutes before your first food, drink, or other medicine of the day. Swallow the tablet whole – do not crush, chew, or suck it. Remain fully upright (sitting or standing) for at least 30 minutes after taking it and do not lie down, to reduce the risk of irritation to the oesophagus (food pipe).
Dosage
The usual dose of Apo-Alendronate 70mg Tablet is one tablet once weekly, taken on the same day each week. Your doctor will confirm the dosing schedule appropriate for your condition and may recommend calcium and vitamin D supplementation alongside this medicine.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Stomach upset or abdominal pain
- Nausea or indigestion
- Constipation or diarrhea
- Muscle or joint pain
- Headache
- Difficulty swallowing (rare but serious)
- Irritation or ulceration of the esophagus (with improper use)
Contraindications
- Known hypersensitivity to alendronate or any ingredient in this product
- Abnormalities of the oesophagus that delay oesophageal emptying (e.g. stricture, achalasia)
- Inability to stand or sit upright for at least 30 minutes after taking the tablet
- Low blood calcium levels (hypocalcaemia) that have not been corrected
- Severe kidney impairment
Drug / Food Interactions
- Calcium supplements, antacids, and mineral supplements significantly reduce absorption if taken too close together – space them apart by at least 30 minutes
- NSAIDs (e.g. ibuprofen, aspirin) may increase the risk of stomach and oesophageal irritation when combined
- Coffee, tea, mineral water, and juice all reduce absorption if taken with or soon after the tablet
- Other bisphosphonates should not be taken at the same time
Quick Tips
- Take with plain water only, first thing in the morning, on an empty stomach
- Stay upright for at least 30 minutes after taking it and do not lie back down
- Wait at least 30 minutes before eating, drinking anything else, or taking other medicines
- Report any difficulty or pain swallowing, or new chest pain/heartburn, to your doctor promptly
Frequently Asked Questions
What is Apo-Alendronate 70mg Tablet used for?
Apo-Alendronate 70mg Tablet is used to treat and prevent osteoporosis, helping to strengthen bones and reduce the risk of fractures, particularly in postmenopausal women and people at risk of bone thinning.
Why do I need to stay upright after taking this tablet?
Alendronate can irritate the oesophagus (food pipe) if it comes into prolonged contact with it. Staying upright and taking it with plenty of water helps the tablet pass quickly into the stomach and reduces this risk.
Can I take calcium supplements at the same time as this medicine?
No, calcium and other mineral supplements should be taken at least 30 minutes apart from alendronate (and ideally later in the day), as they significantly reduce its absorption if taken too close together.
How long do I need to take this medicine for osteoporosis?
Treatment duration varies by individual – many people take alendronate for several years, and your doctor may periodically reassess whether to continue, adjust, or take a break from treatment based on your bone density and fracture risk.
What should I do if I miss a dose of Apo-Alendronate 70mg Tablet?
If you miss your weekly dose, take it the morning after you remember, then return to taking one tablet on your originally chosen day the following week. Do not take two tablets on the same day to make up for a missed dose.
Can I buy Apo-Alendronate 70mg Tablet from DoctorOnCall?
Yes, Apo-Alendronate 70mg Tablet is available through DoctorOnCall, a licensed online pharmacy serving our Malaysian and Singaporean customers. As this is a prescription medicine, you will need to complete an online consultation so a doctor can assess your suitability and issue a valid prescription before the order is processed. This ensures the medicine is appropriate for your condition and used under proper medical supervision, whether you are ordering from Malaysia or Singapore.
Is the medication provided by DoctorOnCall genuine and safe to use?
DoctorOnCall sources its medicines through appropriate licensed pharmacy supply channels for our Malaysian and Singaporean customers. All orders are dispensed and checked by a registered pharmacist before delivery. Always use Apo-Alendronate 70mg Tablet according to your doctor’s instructions and the information provided with the product.
What payment methods does DoctorOnCall accept?
We accept payment via Online Banking, Credit Card, and e-Wallets (Boost, GrabPay) for our Malaysian and Singaporean customers, so you can choose whichever method is most convenient for you at checkout.
Does DoctorOnCall provide an installment payment plan for Apo-Alendronate 70mg Tablet?
DoctorOnCall provides an installment payment plan for eligible Malaysian and Singaporean customers, where applicable. Available plans, eligibility, and terms can vary by market, so please contact DoctorOnCall Customer Service for the latest information on installment options for your order.
Is delivery free, and how much does shipping for Apo-Alendronate 70mg Tablet cost?
Delivery charges may vary for our Malaysian and Singaporean customers depending on your delivery location and the applicable order terms at the time of purchase. For the most accurate and up-to-date delivery fee information, please contact DoctorOnCall Customer Service before placing your order.
How long does delivery take for Apo-Alendronate 70mg Tablet?
Our Malaysian customers can generally expect delivery within 3-5 working days, while our Singaporean customers generally receive their orders within 5-7 working days. These are expected timeframes rather than guarantees, and actual delivery time may vary depending on your delivery location, order processing time, courier operations, and whether the order falls on a weekend or public holiday.
What is DoctorOnCall’s shipping, return, or cancellation policy for Apo-Alendronate 70mg Tablet?
Shipping, return, and cancellation terms may vary for our Malaysian and Singaporean customers depending on the product and your order details. Please refer to DoctorOnCall’s Shipping & Delivery Policy and Return, Refund & Exchange Policy, or contact Customer Service, for the specific terms that apply to your order.
Ingredients / Active Ingredients
- Alendronate (alendronic acid) 70mg
Safety Advice
Pregnancy
Use during pregnancy is generally not recommended unless absolutely necessary.
Breastfeeding
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Generally safe, but caution may be required in some patients.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
This medicine is generally safe and should not impair your driving ability.
Medical Review
