Aprovel 300mg Tablet

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Manufacturer Sanofi
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Dr. Mohd Izzat Amir Bin Awang
Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester
Dr. Adeline Carol Peters
Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated:

Overview

Aprovel 300mg Tablet contains Irbesartan 300mg and is available as a tablet. It is classified as a prescription medicine and may only be obtained with a valid prescription from a registered medical practitioner.

Only product, safety and handling information is published here. Anything beyond that is explained to you directly by your doctor or pharmacist as part of your consultation.

DoctorOnCall is a licensed online pharmacy. Orders for Aprovel 300mg Tablet are processed only after a doctor has assessed your suitability and issued a prescription, and every order is checked by a registered pharmacist before it is sent out.

Directions for Use

Take Aprovel 300mg Tablet exactly as prescribed by your doctor, usually once daily at the same time each day, with or without food. Swallow the tablet whole with a glass of water, and continue taking it regularly even if you feel well, as blood pressure control needs to be maintained continuously.

Dosage

The 300mg dose is generally used as a maintenance dose once daily for patients whose blood pressure or kidney protection needs are not fully controlled on the lower 150mg strength, as determined by the prescribing doctor. Do not adjust your own dose or switch between strengths without medical advice, as the correct dose depends on individual blood pressure response and kidney function.

Shelf Life

Aprovel 300mg Tablet is typically stable for up to 36 months from the date of manufacture when stored correctly and unopened; always check the expiry date printed on the packaging and do not use tablets that have expired.

Storage Instructions

Store below 30°C in a dry place away from direct light and moisture, in the original packaging until ready to use. Keep out of reach of children and pets at all times.

Side Effects

  • Dizziness or lightheadedness, especially when standing up
  • Fatigue or tiredness
  • Nausea
  • Headache
  • High potassium levels (may show as muscle weakness or irregular heartbeat)
  • Back pain

Contraindications

  • Known hypersensitivity to irbesartan or any component of the tablet
  • Pregnancy or planning pregnancy, as ARBs can harm the developing baby
  • Severe liver impairment
  • Concurrent use with aliskiren-containing medicines in patients with diabetes or kidney impairment
  • Bilateral renal artery stenosis or significant kidney artery narrowing

Drug / Food Interactions

  • Potassium-sparing diuretics, potassium supplements, or salt substitutes may cause dangerously high potassium levels when combined
  • NSAIDs may reduce the blood-pressure-lowering effect and affect kidney function, especially in older adults or those with existing kidney impairment
  • Lithium levels may rise when taken with ARBs, requiring monitoring
  • Other antihypertensive medicines or diuretics may increase the blood-pressure-lowering effect
  • Dual use with ACE inhibitors or aliskiren is generally not recommended due to increased risk of kidney problems and hyperkalaemia

Quick Tips

  • Attend all scheduled follow-up appointments so your doctor can monitor blood pressure and kidney function
  • Rise slowly from sitting or lying down to reduce dizziness, especially when starting treatment or increasing the dose
  • Do not use potassium supplements or salt substitutes without discussing this with your doctor
  • Inform your doctor if you become pregnant or are planning to conceive while on this medicine
  • Keep taking the medicine as prescribed even if your blood pressure feels normal, as this reflects the medicine working correctly

Ingredients / Active Ingredients

  • Irbesartan 300mg (active ingredient, angiotensin II receptor blocker)
  • Standard tablet excipients including fillers and binders
  • Irbesartan 300mg

Safety Advice

Pregnancy

Not Safe

This medicine is not considered safe during pregnancy and should be avoided.

Breastfeeding

Limited Data

Limited data on excretion in breast milk. Consult a doctor before use.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Not Advisable

It is not advisable to consume alcohol while taking this medicine.

Driving

Not Advisable

It is not advisable to drive if you experience side effects from this medicine.

Relevant Information

Aprovel 300mg Tablet requires ongoing medical supervision, as regular blood pressure checks and periodic kidney function and electrolyte monitoring help ensure the higher maintenance dose continues to work safely and effectively. Patients should not discontinue treatment on their own, as stopping abruptly can lead to a rebound in blood pressure.

Frequently Asked Questions

Product Specifications

BrandSanofi-Aventis
ManufacturerSanofi
ClassificationPrescription medicine
Ingredients / Active IngredientsIrbesartan
Pack Size14s, 28s

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