Arava 20mg Tablet
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Prescription Required
Overview
Arava 20mg Tablet is a prescription-only medicine (POM) presented as a tablet, with Leflunomide 20mg as its active ingredient content.
This page is limited to product, safety and handling information, in line with Malaysian rules on prescription medicine information for the public. Your prescriber or pharmacist is the right source for anything beyond that, together with the leaflet inside the pack.
Through DoctorOnCall, this product is supplied after an online consultation with a licensed doctor and a valid prescription, and it is checked by a registered pharmacist before dispensing. Take it exactly as prescribed, and speak to your doctor before stopping, changing the dose, or starting any other medicine alongside it.
Directions for Use
Take Arava 20mg Tablet at the same time each day, with or without food, swallowing the tablet whole. Do not stop or change your dose without consulting your rheumatologist. Because leflunomide has a very long half-life, an accelerated elimination procedure (using cholestyramine or activated charcoal) may be needed if treatment must be stopped, especially before planning a pregnancy – this must only be done under medical supervision.
Dosage
The usual maintenance dose of Arava 20mg Tablet is 10-20mg once daily as directed by your rheumatologist. A loading dose may be used at the very start of treatment in some cases, but only under specialist supervision. Regular monitoring of liver function, full blood count, and blood pressure is required throughout treatment.
Shelf Life
Use this product before the expiry date stated on the packaging. Do not use the medicine if the expiry date has passed.
Storage Instructions
Store below 30°C in a dry place, away from direct sunlight and out of reach of children.
Side Effects
- Nausea or upset stomach
- Diarrhoea
- Headache
- Hair thinning or hair loss
- Elevated liver enzymes
- Skin rash
- Loss of appetite
Contraindications
- Known hypersensitivity to leflunomide
- Pregnancy, and women or men not using reliable contraception, due to the teratogenic risk
- Severe hepatic impairment
- Severe immunodeficiency or significant bone marrow suppression/anaemia
- Severe uncontrolled infection
Drug / Food Interactions
- Methotrexate combined with leflunomide increases the risk of liver toxicity
- Live vaccines should be avoided during treatment
- Warfarin’s anticoagulant effect may be increased, requiring closer INR monitoring
- Rifampicin can increase leflunomide’s active metabolite levels
- Cholestyramine or activated charcoal is used deliberately for the washout procedure, but otherwise reduces leflunomide levels if taken together
Quick Tips
- Attend every scheduled liver function test, full blood count, and blood pressure check
- Use effective contraception throughout treatment and discuss the washout procedure with your doctor well before trying to conceive
- Report any signs of infection to your doctor promptly
- Avoid live vaccines without checking with your rheumatologist, and never stop treatment abruptly without medical advice
Frequently Asked Questions
Is Arava 20mg Tablet a prescription medicine?
Yes. Arava 20mg Tablet is a prescription-only medicine (POM). It can only be supplied against a valid prescription written by a registered doctor, and it should be used only by the person named on the prescription label.
What does Arava 20mg Tablet contain?
Arava 20mg Tablet is supplied as a tablet and contains Leflunomide 20mg. The full composition is listed in the Composition section on this page and on the product packaging.
Why is there no information here about what Arava 20mg Tablet is for?
Malaysian rules for prescription medicines limit public product pages to product, safety and handling information. Your doctor decides whether this medicine is appropriate for you and will explain it during your consultation, and your pharmacist can answer further questions when the medicine is dispensed.
How should I take Arava 20mg Tablet?
Take it exactly as written on your prescription label. Do not increase, reduce or skip doses on your own, and do not continue beyond the period your doctor has prescribed. Practical handling steps are set out in the Directions for Use section on this page.
What should I do if I miss a dose?
Take it as soon as you remember, unless your next dose is nearly due. In that case skip the missed dose and carry on with your usual schedule. Never take two doses together to make up for a missed one. If you miss doses often, tell your doctor or pharmacist.
How should I store Arava 20mg Tablet?
Store below 30°C in a dry place, away from direct sunlight and out of reach of children. Keep it in the original pack until use, and do not use it after the expiry date printed on the packaging.
What should I do if I notice side effects?
Tell your doctor or pharmacist about any reaction that concerns you, and seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Can I stop taking Arava 20mg Tablet on my own?
No. Speak to your doctor before stopping, pausing or changing the dose, even if you feel well or think you no longer need the medicine.
How do I get a prescription for Arava 20mg Tablet?
Customers in Malaysia can complete an online consultation with a DoctorOnCall doctor, who decides whether a prescription is appropriate, or upload a valid prescription already issued by their own doctor.
Orders going to Singapore are dispatched from Malaysia as an international delivery, so you need to hold a valid prescription or doctor’s letter for the medicine. Check the consultation and prescription upload options shown at checkout for your delivery address before placing the order.
How long will delivery take?
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
What payment methods can I use?
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Can Arava 20mg Tablet be delivered to Singapore?
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Is Arava 20mg Tablet registered with the authorities?
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
Who do I contact if there is a problem with my order?
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Ingredients / Active Ingredients
- Leflunomide 20mg
Safety Advice
Pregnancy
This medicine is not considered safe during pregnancy and should be avoided.
Breastfeeding
Generally not recommended while breastfeeding.
Kidney
Use cautiously. Dose adjustment or monitoring may be required.
Liver
Use cautiously. Liver function monitoring may be required.
Alcohol
It is not advisable to consume alcohol while taking this medicine.
Driving
Use caution while driving until you know how this medicine affects you.
