Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)
Last updated:
Overview
Dyfenamic 500mg Tablet is a tablet with Mefenamic Acid 500mg declared as its active content. It is supplied in a pack size of 10s.
This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.
An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.
Directions for Use
Take Dyfenamic 500mg Tablet by mouth exactly as directed by your prescribing doctor, generally with or after food to reduce the risk of stomach upset, and swallow the tablet whole with a full glass of water; do not take more than the prescribed dose or for longer than the course advised, as prolonged NSAID use increases the risk of side effects.
Dosage
The typical adult starting dose is 500mg, followed by 250mg every 6 hours as needed, usually for no more than 7 days unless a doctor directs otherwise; the lowest effective dose for the shortest duration necessary should be used, and dosing in the elderly, in those with kidney or liver impairment, or in adolescents will be individualised by the prescribing doctor.
Storage Instructions
Store Dyfenamic 500mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, keep it in the original packaging until ready to use, and keep it out of the reach and sight of children.
Side Effects
Stomach pain or discomfort
Nausea or vomiting
Diarrhea or constipation
Headache
Dizziness
Skin rash
Heartburn or indigestion
Contraindications
Known hypersensitivity to mefenamic acid, aspirin, or other NSAIDs, including a history of asthma, urticaria, or allergic-type reactions triggered by these medicines
Active or past peptic ulcer disease or gastrointestinal bleeding
Severe kidney, liver, or heart failure
Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
Third trimester of pregnancy
Active bleeding disorders
Drug / Food Interactions
Increases the risk of bleeding when combined with anticoagulants (e.g. warfarin) or antiplatelet medicines (e.g. aspirin, clopidogrel)
Should not generally be combined with other NSAIDs, as this increases the risk of gastrointestinal and kidney side effects without added benefit
May reduce the effectiveness of some blood pressure medicines and increase kidney strain when combined with ACE inhibitors, ARBs, or diuretics
Can increase blood levels of lithium and methotrexate, raising the risk of toxicity
Taking with food can help reduce stomach irritation
Quick Tips
Take with food or a full glass of water to reduce stomach upset
Use the lowest effective dose for the shortest time necessary, as advised by your doctor
Stay well hydrated, particularly in hot weather or with reduced fluid intake
Do not combine with other NSAIDs or aspirin unless specifically advised by your doctor
Report any signs of stomach pain, black stools, unusual bruising, or reduced urine output promptly
Attend follow-up review if a longer course is needed, so your doctor can monitor for side effects
This medicine should only be used during pregnancy if prescribed by a doctor after careful evaluation.
Breastfeeding
Use With Care
Use with caution. Monitor infant for potential adverse reactions.
Kidney
Safe If Prescribed
Use only if prescribed, with possible monitoring of kidney function.
Liver
Use With Care
Use cautiously. Liver function monitoring may be required.
Alcohol
Use With Care
Caution is advised when consuming alcohol with this medicine.
Driving
Use With Care
Use caution while driving until you know how this medicine affects you.
Relevant Information
Mefenamic acid is a commonly prescribed NSAID in Malaysia and Singapore for short-term relief of pain and inflammation, particularly menstrual cramps and mild-to-moderate musculoskeletal or dental pain. Because NSAIDs as a class carry risks to the stomach, kidneys, and cardiovascular system — risks that increase with higher doses, longer use, or in patients with existing health conditions — DoctorOnCall requires an online medical consultation before dispensing Dyfenamic 500mg Tablet, so a doctor can confirm it is a suitable and safe choice for you.
Frequently Asked Questions
No. Dyfenamic 500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.
Dyfenamic 500mg Tablet is a tablet containing Mefenamic Acid 500mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.
It is supplied in a pack size of 10s. Choose the pack size you need from the options shown on this page before adding the item to your cart.
This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.
Use it exactly as stated on the pack label, without changing the amount or how often you use it. If anything on the label is unclear, check with a pharmacist before the first use, and read the Directions for Use section on this page.
Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.
Store Dyfenamic 500mg Tablet below 30°C in a cool, dry place away from direct sunlight and moisture, keep it in the original packaging until ready to use, and keep it out of the reach and sight of children. Keep it in its original pack and do not use it after the expiry date printed on the packaging.
Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.
Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day.
Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.
Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay.
FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.
Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee.
Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.
Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number.
An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.
DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre.
For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.
Product Specifications
Classification
Non-prescription
Ingredients / Active Ingredients
Mefenamic Acid
Pack Size
10s
Shelf Life
Dyfenamic 500mg Tablet is generally stable until the expiry date printed on the blister strip and carton when stored correctly; do not use the tablets beyond this date, and check the expiry date before each use.
What condition or symptom are you treating with this medication?
Please select your condition / symptom before adding to cart.
*Please select the closest match. A pharmacist may call to verify your selection before dispensing.
Important Medical Information
💊 Recommended Dosage:
The typical adult starting dose is 500mg, followed by 250mg every 6 hours as needed, usually for no more than 7 days unless a doctor directs otherwise; the lowest effective dose for the shortest duration necessary should be used, and dosing in the elderly, in those with kidney or liver impairment, or in adolescents will be individualised by the prescribing doctor.
🛑 Contraindications (Do not use if):
Known hypersensitivity to mefenamic acid, aspirin, or other NSAIDs, including a history of asthma, urticaria, or allergic-type reactions triggered by these medicines
Active or past peptic ulcer disease or gastrointestinal bleeding
Severe kidney, liver, or heart failure
Inflammatory bowel disease (Crohn’s disease or ulcerative colitis)
Third trimester of pregnancy
Active bleeding disorders
If you are unsure, please chat with us or consult your doctor.
⚠️ Common Side Effects:
Stomach pain or discomfort
Nausea or vomiting
Diarrhea or constipation
Headache
Dizziness
Skin rash
Heartburn or indigestion
Stop taking this medication immediately and consult your doctor if you experience severe allergic reactions or side effects.
Please tick this box to confirm you are 18+ before adding to cart.
IMPORTANT: Unsure? Chat with our pharmacists (Mon - Sat, 9:00am - 6:00pm) before buying.