Do I need a prescription to buy Glucophage 500mg Tablet?

No. Glucophage 500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Glucophage 500mg Tablet contain?

Glucophage 500mg Tablet is a tablet containing Metformin Hydrochloride 500mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Glucophage 500mg Tablet come in?

It is supplied in pack sizes of 120s and 20s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Glucophage 500mg Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Glucophage 500mg Tablet?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Glucophage 500mg Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

What should I do if I notice side effects after using Glucophage 500mg Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Glucophage 500mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Glucophage 500mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Glucophage 500mg Tablet | metformin | type 2 diabetes first-line glucose tablet | DoctorOnCall Malaysia

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Glucophage 500mg Tablet

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Manufacturer Merck

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Adeline Carol PetersBachelor of Medicine and Bachelor of Surgery (MBBS) — Manipal Academy of Higher Education (MAHE)

Last updated: November 3, 2026

Overview

Glucophage 500mg Tablet is a tablet with Metformin Hydrochloride 500mg declared as its active content. It is supplied in pack sizes of 120s and 20s.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Glucophage 500mg Tablet should only be taken according to a doctor’s prescription, following the dose, frequency, and duration advised. It is usually taken with or immediately after meals to reduce gastrointestinal discomfort, and the tablet should be swallowed whole with a glass of water rather than crushed or chewed, unless a doctor advises otherwise.

Dosage

Dosing is individualised by the prescribing doctor, typically starting at a low dose such as 500mg once or twice daily with meals, and gradually increased over one to two weeks based on blood glucose response and tolerability, up to a maximum daily dose determined by the doctor. Patients should never adjust their own dose or stop treatment without medical advice, as this can affect blood sugar control.

Shelf Life

Glucophage 500mg Tablet is generally valid for up to 36 months from the date of manufacture when stored correctly and unopened; the exact expiry date is printed on the blister strip and outer carton and should be checked before each use.

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight and moisture, keeping tablets in their original blister packaging until needed. Keep out of reach and sight of children, and discard any tablets that are damaged, discoloured, or past their expiry date.

Side Effects

Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)

Contraindications

Known hypersensitivity to metformin or any ingredient in the tablet
Severe renal impairment or acute kidney injury
Conditions predisposing to tissue hypoxia, such as severe heart failure or respiratory failure
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Severe liver impairment
Should be temporarily stopped before procedures involving iodinated contrast media, as advised by a doctor

Drug / Food Interactions

Alcohol may increase the risk of lactic acidosis and should be limited or avoided
Iodinated contrast media used in imaging studies can increase the risk of kidney impairment and lactic acidosis when combined with metformin
Certain diuretics, corticosteroids, and other medicines that raise blood glucose may reduce metformin’s effectiveness
Cimetidine and some other medicines can increase metformin blood levels
Should be used cautiously with other antidiabetic medicines due to increased risk of hypoglycaemia when combined

Quick Tips

Take Glucophage with or immediately after meals to reduce stomach upset.
Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor advises otherwise.
Limit or avoid alcohol, as it can increase the risk of lactic acidosis when combined with metformin.
Keep all scheduled blood tests to check your kidney function and vitamin B12 levels, especially with long-term use.
Tell your doctor before any scan or procedure involving iodinated contrast dye, as metformin may need to be temporarily stopped.
Do not double up on a missed dose — simply take your next dose at the usual time.
Seek urgent medical attention if you notice unusual muscle pain, difficulty breathing, or severe tiredness, as these may signal lactic acidosis.
Store tablets in their original blister packaging, away from moisture and heat.

Ingredients / Active Ingredients

Metformin

Metformin Hydrochloride 500mg (active ingredient)
Povidone
Magnesium stearate
Hypromellose (film coating)
Macrogol
Purified water (processing aid)

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Glucophage 500mg Tablet is a prescription-only medicine in Malaysia, and DoctorOnCall requires an online medical consultation before it can be dispensed, so a doctor can confirm suitability and monitor kidney function and blood glucose control over time. Patients on long-term therapy should have periodic blood tests as advised by their doctor, and should seek medical attention immediately if symptoms such as unusual muscle pain, difficulty breathing, or severe tiredness develop, as these may indicate lactic acidosis.