Do I need a prescription to buy Glymet 2.5/500mg Tablet?

No. Glymet 2.5/500mg Tablet is a non-prescription product and can be ordered without a prescription. It is still dispensed by a registered pharmacist on DoctorOnCall.

What does Glymet 2.5/500mg Tablet contain?

Glymet 2.5/500mg Tablet is a tablet containing Glibenclamide 2.5mg. The full ingredient list is shown in the Composition or Ingredients section on this page and on the product packaging.

What pack sizes does Glymet 2.5/500mg Tablet come in?

It is supplied in a pack size of 56s. Choose the pack size you need from the options shown on this page before adding the item to your cart.

Why is there no information here about what Glymet 2.5/500mg Tablet is for?

This page is limited to product, safety and handling information in line with Malaysian rules on medicine information. If you want advice on whether this product suits you, book an online consultation with a doctor or pharmacist on DoctorOnCall.

How should I use Glymet 2.5/500mg Tablet?

Follow the instructions printed on the label and in the leaflet supplied with the pack, and do not exceed the stated amount or duration. Handling steps are set out in the Directions for Use section on this page.

Can I speak to a doctor or pharmacist about Glymet 2.5/500mg Tablet before I buy it?

Yes. DoctorOnCall offers online consultations with licensed doctors and registered pharmacists, so you can ask about this product, your existing medicines, or anything on the label before you place an order.

What should I do if I notice side effects after using Glymet 2.5/500mg Tablet?

Stop using the product and speak to a doctor or pharmacist about any reaction that concerns you. Seek medical care immediately for signs of a severe reaction such as difficulty breathing, swelling of the face, lips or throat, or a widespread rash. Reported reactions are listed in the Side Effects section on this page.

How long will delivery take?

Within Malaysia, standard delivery takes 3 to 5 working days. Same-day delivery is available in the Klang Valley for orders placed before 12pm; orders placed after 12pm arrive by the end of the next day. Orders to Singapore are sent as international deliveries and take 5 to 9 working days. A lump-sum shipping and handling fee applies to every overseas delivery and is shown at checkout.

What payment methods can I use?

Customers in Malaysia can pay by FPX online banking, credit or debit card (Visa and Mastercard), and supported e-wallets including Touch ‘n Go eWallet, GrabPay and ShopeePay. FPX and local e-wallets are tied to Malaysian bank and wallet accounts, so if your delivery address is in Singapore, use the payment options displayed at checkout for that address rather than assuming the same list applies.

Can Glymet 2.5/500mg Tablet be delivered to Singapore?

Yes. DoctorOnCall ships to Singapore as an international order dispatched from Malaysia, arriving in 5 to 9 working days with a lump-sum shipping and handling fee. Singapore’s Health Sciences Authority (HSA) allows personal imports of up to three months’ supply of a medicine for your own use or an immediate family member’s, as long as it contains no controlled drugs, psychotropic substances or prohibited items. Keep the product in its original labelled packaging and keep a copy of your prescription or doctor’s letter with it. Quantities above three months’ supply, and medicines containing controlled substances, require prior HSA approval.

Is Glymet 2.5/500mg Tablet registered with the authorities?

Products listed on DoctorOnCall are registered with Malaysia’s Ministry of Health for supply in Malaysia, and each pack carries its MAL registration number. An order delivered to Singapore arrives as a personal import of a Malaysia-registered product; HSA product registration is not required for personal-use quantities, but it is also not the same as a product registered for sale in Singapore. If you need a locally registered Singapore product, buy it from a pharmacy in Singapore.

Who do I contact if there is a problem with my order?

DoctorOnCall’s customer care team handles order, delivery and product queries through the contact channels on the site, including WhatsApp and the online help centre. For deliveries to Singapore, allow more time before chasing an order than you would for a local Malaysian delivery, as the parcel passes through customs clearance and tracking updates can appear later in the journey.

Glymet 2.5/500mg Tablet | glibenclamide metformin | type 2 diabetes combination tablet | DoctorOnCall Malaysia

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Glymet 2.5/500mg Tablet

Brand Orient Europharma

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Reviewed byDr. Mohd Izzat Amir Bin AwangDoctor of Medicine (MD), University of Mansoura - Manchester

Written byDr. Chong Zhan PongDoctor of Medicine (MD), International Medical University (IMU)

Last updated: October 15, 2026

Overview

Glymet 2.5/500mg Tablet is a tablet with Glibenclamide 2.5mg declared as its active content. It is supplied in a pack size of 56s.

This is a non-prescription product and can be purchased without a prescription. Only product, safety and handling details are published on this page.

An online consultation with a DoctorOnCall doctor or pharmacist is available for this product, and a registered pharmacist reviews each order before dispatch to Malaysia or Singapore. Follow the directions on the label and on the leaflet inside the pack.

Directions for Use

Glymet 2.5/500mg Tablet should only be taken according to the dose and schedule prescribed by your doctor following an online consultation with DoctorOnCall. Tablets are usually taken with or just after meals to reduce the chance of stomach upset and to lower the risk of hypoglycaemia (low blood sugar). Do not skip meals after taking a dose, and do not change your dose without first consulting your doctor.

Dosage

The dosage of Glymet 2.5/500mg Tablet is determined individually by your prescribing doctor based on your blood glucose readings, kidney function, and response to treatment, and is usually started at a low dose and adjusted gradually. Always follow the exact dose and timing given on your prescription, and attend scheduled blood tests so your doctor can monitor your kidney function and blood sugar control.

Shelf Life

Glymet 2.5/500mg Tablet is generally stable for up to 24 to 36 months from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the blister strip or carton before use, and do not take the tablets if the date has passed.

Storage Instructions

Store Glymet 2.5/500mg Tablet at room temperature, below 30 degrees Celsius, in a dry place away from direct sunlight and moisture. Keep the tablets in their original packaging until ready to use, and keep out of reach of children.

Side Effects

Nausea or vomiting
Diarrhea
Stomach discomfort or cramps
Metallic taste in the mouth
Loss of appetite
Weight loss (in some cases)

Contraindications

Known hypersensitivity to glibenclamide, metformin, or sulfonylureas in general
Severe kidney or liver impairment
Type 1 diabetes or diabetic ketoacidosis
Severe infection, dehydration, or conditions that increase the risk of lactic acidosis
Not recommended during pregnancy or breastfeeding unless specifically advised by a doctor
Should be temporarily stopped before procedures using iodinated contrast media

Drug / Food Interactions

Alcohol may increase the risk of hypoglycaemia and lactic acidosis
Certain diuretics, corticosteroids, and other medicines that raise blood glucose may reduce the effectiveness of Glymet 2.5/500mg Tablet
NSAIDs and some antibiotics may increase the blood glucose-lowering effect and hypoglycaemia risk
Iodinated contrast dye used in certain X-ray or scan procedures may increase the risk of lactic acidosis when combined with metformin
Inform your doctor of all other medicines, supplements, and herbal products you are taking

Quick Tips

Take Glymet 2.5/500mg Tablet with or just after meals and do not skip meals
Monitor your blood glucose as advised and know the signs of hypoglycaemia, such as sweating, shakiness, or confusion
Carry a fast-acting source of sugar in case of a hypoglycaemic episode
Attend regular follow-up appointments and blood tests as scheduled by your doctor
Tell your doctor if you become unwell, dehydrated, or need any surgery or imaging with contrast dye

Ingredients / Active Ingredients

Metformin

Glibenclamide 2.5mg
Metformin Hydrochloride 500mg

Safety Advice

Pregnancy

Use With Care

This medicine should be used cautiously during pregnancy. Monitoring may be required.

Breastfeeding

Generally Safe

This medicine is generally safe during breastfeeding with minimal risk to the infant.

Kidney

Use With Care

Use cautiously. Dose adjustment or monitoring may be required.

Liver

Use With Care

Use cautiously. Liver function monitoring may be required.

Alcohol

Use With Care

Caution is advised when consuming alcohol with this medicine.

Driving

Use With Care

Use caution while driving until you know how this medicine affects you.

Relevant Information

Glymet 2.5/500mg Tablet is usually prescribed as part of a broader diabetes management plan that includes a balanced diet, regular physical activity, and routine monitoring of blood glucose and HbA1c levels. Because it combines a sulfonylurea and a biguanide, patients need to be particularly aware of the risk of hypoglycaemia from the glibenclamide component and should not stop or adjust treatment without medical advice. Regular follow-up with your doctor helps ensure the combination remains appropriate as your kidney function and overall health status change over time.