Gofen 400mg Capsule

Gofen 400mg Capsule contains ibuprofen 400mg, a widely used nonsteroidal anti-inflammatory drug (NSAID) from the propionic acid group. It works by reducing the production of prostaglandins, chemical messengers in the body responsible for pain, fever, and inflammation, providing relief from mild to moderate pain and reducing swelling associated with musculoskeletal conditions.

In Malaysia, Gofen 400mg Capsule is classified as a Poison List C medicine, meaning it can be purchased over the counter without a doctor’s prescription, but only under the supervision of a registered pharmacist who can advise on correct use and screen for risk factors. It is commonly used to relieve headache, toothache, menstrual cramps, muscle and joint pain, and fever, and to ease inflammation from minor injuries or sprains.

Ibuprofen works by inhibiting the cyclooxygenase (COX-1 and COX-2) enzymes, which reduces the production of prostaglandins in the body. Since prostaglandins trigger pain signals, promote inflammation, and raise body temperature during fever, lowering their levels helps relieve pain, reduce swelling, and bring down a raised temperature within a short time of taking the capsule.

Gofen 400mg Capsule should be swallowed whole with a full glass of water, preferably with or after food or milk to reduce the risk of stomach upset. It should be taken at the lowest effective dose for the shortest duration needed to control symptoms, and the capsule should not be crushed, chewed, or opened before swallowing.

The usual adult dose is one 400mg capsule taken every 6 to 8 hours as needed for pain or fever, up to a maximum of 1200mg (three capsules) in 24 hours unless a pharmacist or doctor advises otherwise. Gofen is not recommended for children under 12 years old or for individuals under 40kg without professional guidance, and the lowest effective dose should always be used for the shortest possible time.

Gofen 400mg Capsule generally has a shelf life of up to 3 years from the date of manufacture when unopened and stored correctly, and the specific expiry date is printed on the outer packaging and capsule blister strip.

Store Gofen 400mg Capsule below 30°C in a cool, dry place away from direct sunlight and moisture, and keep it in its original packaging out of the reach and sight of children.

• Nausea, stomach discomfort, or heartburn
• Indigestion or bloating
• Headache or dizziness
• Diarrhoea or constipation
• Skin rash or itching
• Drowsiness (uncommon)
• Ringing in the ears (tinnitus) with prolonged high-dose use
• Fluid retention or mild swelling of the ankles

• Active or history of peptic ulcer or gastrointestinal bleeding
• Known hypersensitivity to ibuprofen, aspirin, or other NSAIDs, including asthma, wheezing, or hives triggered by these medicines
• Severe heart failure, kidney impairment, or liver impairment
• Third trimester of pregnancy
• Active, uncontrolled bleeding disorders
• Children under 12 years old without medical advice

• Increased bleeding risk when taken with anticoagulants such as warfarin
• Reduced effectiveness when combined with other NSAIDs or aspirin, with higher GI risk
• May reduce the effectiveness of ACE inhibitors, ARBs, and diuretics, and increase the risk of kidney problems when combined
• Increased risk of stomach irritation or bleeding with corticosteroids or other NSAIDs
• May raise blood levels of methotrexate or lithium when taken together
• Alcohol may increase the risk of stomach irritation during treatment

• Take Gofen with food or milk to reduce stomach upset
• Do not exceed the maximum daily dose of 1200mg unless advised by a pharmacist or doctor
• Avoid taking together with other NSAIDs or aspirin unless directed
• Stop use and seek medical advice if you notice black stools, vomiting blood, or persistent stomach pain
• Use the lowest effective dose for the shortest time needed
• Consult a pharmacist before use if you are pregnant, breastfeeding, or have chronic heart, kidney, or liver conditions

Gofen 400mg Capsule is a Poison List C medicine in Malaysia, which means it is dispensed over the counter by a registered pharmacist rather than requiring a doctor’s prescription. Pharmacist counselling helps ensure the medicine is suitable, particularly for individuals with existing stomach, heart, kidney, or liver conditions, or those taking other regular medications.

Patients using ibuprofen for more than a few days for ongoing pain or fever should follow up with a doctor to identify the underlying cause, as NSAIDs are intended for short-term symptom relief rather than long-term use without medical supervision.